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Items: 1 to 20 of 131

1.

(S)-1-α-naphthylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712), promotes wound closure by producing VEGF through HO-1 induction in human dermal fibroblasts and mouse skin.

Jang HJ, Tsoyi K, Kim YM, Park EJ, Park SW, Kim HJ, Lee JH, Chang KC.

Br J Pharmacol. 2013 Mar;168(6):1485-96. doi: 10.1111/bph.12031.

2.

HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride.

Tsoyi K, Kim HJ, Shin JS, Kim DH, Cho HJ, Lee SS, Ahn SK, Yun-Choi HS, Lee JH, Seo HG, Chang KC.

Cell Signal. 2008 Oct;20(10):1839-47. doi: 10.1016/j.cellsig.2008.06.012. Epub 2008 Jun 27.

PMID:
18634870
3.
4.

Upregulation of PTEN by CKD712, a synthetic tetrahydroisoquinoline alkaloid, selectively inhibits lipopolysaccharide-induced VCAM-1 but not ICAM-1 expression in human endothelial cells.

Tsoyi K, Kim WS, Kim YM, Kim HJ, Seo HG, Lee JH, Yun-Choi HS, Chang KC.

Atherosclerosis. 2009 Dec;207(2):412-9. doi: 10.1016/j.atherosclerosis.2009.05.012. Epub 2009 May 21.

PMID:
19540498
5.

Effect of heme and heme oxygenase-1 on vascular endothelial growth factor synthesis and angiogenic potency of human keratinocytes.

Jazwa A, Loboda A, Golda S, Cisowski J, Szelag M, Zagorska A, Sroczynska P, Drukala J, Jozkowicz A, Dulak J.

Free Radic Biol Med. 2006 Apr 1;40(7):1250-63. Epub 2005 Dec 19.

6.

Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis.

Webler AC, Michaelis UR, Popp R, Barbosa-Sicard E, Murugan A, Falck JR, Fisslthaler B, Fleming I.

Am J Physiol Cell Physiol. 2008 Nov;295(5):C1292-301. doi: 10.1152/ajpcell.00230.2008. Epub 2008 Sep 11.

7.

CKD712, (S)-1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, inhibits the lipopolysaccharide-stimulated secretion of HMGB1 by inhibiting PI3K and classical protein kinase C.

Oh YJ, Youn JH, Min HJ, Kim DH, Lee SS, Choi IH, Shin JS.

Int Immunopharmacol. 2011 Sep;11(9):1160-5. doi: 10.1016/j.intimp.2011.03.013. Epub 2011 Mar 30.

PMID:
21457762
9.

Delayed cutaneous wound closure in HO-2 deficient mice despite normal HO-1 expression.

Lundvig DM, Scharstuhl A, Cremers NA, Pennings SW, te Paske J, van Rheden R, van Run-van Breda C, Regan RF, Russel FG, Carels CE, Maltha JC, Wagener FA.

J Cell Mol Med. 2014 Dec;18(12):2488-98. doi: 10.1111/jcmm.12389. Epub 2014 Sep 16.

10.

The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts.

Chen CC, Mo FE, Lau LF.

J Biol Chem. 2001 Dec 14;276(50):47329-37. Epub 2001 Oct 2.

11.

Dermal wound healing properties of redox-active grape seed proanthocyanidins.

Khanna S, Venojarvi M, Roy S, Sharma N, Trikha P, Bagchi D, Bagchi M, Sen CK.

Free Radic Biol Med. 2002 Oct 15;33(8):1089-96.

PMID:
12374620
12.

Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.

Wang L, Kou MC, Weng CY, Hu LW, Wang YJ, Wu MJ.

Arch Toxicol. 2012 Jun;86(6):879-96. doi: 10.1007/s00204-012-0845-z. Epub 2012 Apr 10.

PMID:
22488045
13.

Haem oxygenase-1: a novel player in cutaneous wound repair and psoriasis?

Hanselmann C, Mauch C, Werner S.

Biochem J. 2001 Feb 1;353(Pt 3):459-66.

14.

Transforming growth factor-β-activated kinase 1 regulates angiogenesis via AMP-activated protein kinase-α1 and redox balance in endothelial cells.

Zippel N, Malik RA, Frömel T, Popp R, Bess E, Strilic B, Wettschureck N, Fleming I, Fisslthaler B.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2792-9. doi: 10.1161/ATVBAHA.113.301848. Epub 2013 Sep 26.

15.

Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor.

Marinissen MJ, Tanos T, Bolós M, de Sagarra MR, Coso OA, Cuadrado A.

J Biol Chem. 2006 Apr 21;281(16):11332-46. Epub 2006 Feb 13.

16.

A molecular cascade showing nitric oxide-heme oxygenase-1-vascular endothelial growth factor-interleukin-8 sequence in human endothelial cells.

Pae HO, Oh GS, Choi BM, Kim YM, Chung HT.

Endocrinology. 2005 May;146(5):2229-38. Epub 2005 Jan 20.

PMID:
15661856
17.

Formononetin accelerates wound repair by the regulation of early growth response factor-1 transcription factor through the phosphorylation of the ERK and p38 MAPK pathways.

Huh JE, Nam DW, Baek YH, Kang JW, Park DS, Choi DY, Lee JD.

Int Immunopharmacol. 2011 Jan;11(1):46-54. doi: 10.1016/j.intimp.2010.10.003. Epub 2010 Oct 16.

PMID:
20959155
18.

Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase.

Stahmann N, Woods A, Spengler K, Heslegrave A, Bauer R, Krause S, Viollet B, Carling D, Heller R.

J Biol Chem. 2010 Apr 2;285(14):10638-52. doi: 10.1074/jbc.M110.108688. Epub 2010 Feb 3.

19.

Isoflurane preconditioning increases survival of rat skin random-pattern flaps by induction of HIF-1α expression.

Sun Y, Li QF, Zhang Y, Hu R, Jiang H.

Cell Physiol Biochem. 2013;31(4-5):579-91. doi: 10.1159/000350078. Epub 2013 Apr 26.

PMID:
23635649
20.

CXC chemokine receptor 4 is essential for Lipo-PGE1-enhanced migration of human dermal fibroblasts.

Yang Y, Shim SK, Kim HA, Seon M, Yang E, Cho D, Bang SI.

Exp Dermatol. 2012 Jan;21(1):75-7. doi: 10.1111/j.1600-0625.2011.01406.x.

PMID:
22151395
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