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Results: 1 to 20 of 114

1.

Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.

Chavarría C, Perez DI, Pérez C, Morales Garcia JA, Alonso-Gil S, Pérez-Castillo A, Gil C, Souza JM, Porcal W.

Eur J Med Chem. 2012 Dec;58:44-9. doi: 10.1016/j.ejmech.2012.09.044. Epub 2012 Oct 5.

PMID:
23085773
[PubMed - indexed for MEDLINE]
2.

In vitro neuroprotection against oxidative stress by pre-treatment with a combination of dihydrolipoic acid and phenyl-butyl nitrones.

Koenig ML, Meyerhoff JL.

Neurotox Res. 2003;5(4):265-72.

PMID:
12835118
[PubMed - indexed for MEDLINE]
3.

Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.

Chioua M, Sucunza D, Soriano E, Hadjipavlou-Litina D, Alcázar A, Ayuso I, Oset-Gasque MJ, González MP, Monjas L, Rodríguez-Franco MI, Marco-Contelles J, Samadi A.

J Med Chem. 2012 Jan 12;55(1):153-68. doi: 10.1021/jm201105a. Epub 2011 Dec 21.

PMID:
22126405
[PubMed - indexed for MEDLINE]
4.

2-Benzazepine nitrones protect dopaminergic neurons against 6-hydroxydopamine-induced oxidative toxicity.

Soto-Otero R, Méndez-Álvarez E, Sánchez-Iglesias S, Labandeira-García JL, Rodríguez-Pallares J, Zubkov FI, Zaytsev VP, Voskressensky LG, Varlamov AV, de Candia M, Fiorella F, Altomare C.

Arch Pharm (Weinheim). 2012 Aug;345(8):598-609. doi: 10.1002/ardp.201200007. Epub 2012 Apr 25.

PMID:
22532340
[PubMed - indexed for MEDLINE]
5.

Synthesis of a new family of glycolipidic nitrones as potential antioxidant drugs for neurodegenerative disorders.

Durand G, Polidori A, Salles JP, Pucci B.

Bioorg Med Chem Lett. 2003 Mar 10;13(5):859-62.

PMID:
12617908
[PubMed - indexed for MEDLINE]
6.

Heteroarylnitrones as drugs for neurodegenerative diseases: synthesis, neuroprotective properties, and free radical scavenger properties.

Porcal W, Hernández P, González M, Ferreira A, Olea-Azar C, Cerecetto H, Castro A.

J Med Chem. 2008 Oct 9;51(19):6150-9. doi: 10.1021/jm8006432. Epub 2008 Sep 13.

PMID:
18788732
[PubMed - indexed for MEDLINE]
7.

Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.

Samadi A, Soriano E, Revuelta J, Valderas C, Chioua M, Garrido I, Bartolomé B, Tomassolli I, Ismaili L, González-Lafuente L, Villarroya M, García AG, Oset-Gasque MJ, Marco-Contelles J.

Bioorg Med Chem. 2011 Jan 15;19(2):951-60. doi: 10.1016/j.bmc.2010.11.053. Epub 2010 Dec 7.

PMID:
21190861
[PubMed - indexed for MEDLINE]
8.

Antioxidants, oxidative stress, and degenerative neurological disorders.

Floyd RA.

Proc Soc Exp Biol Med. 1999 Dec;222(3):236-45. Review.

PMID:
10601882
[PubMed - indexed for MEDLINE]
9.

Synthesis, structure, and neuroprotective properties of novel imidazolyl nitrones.

Dhainaut A, Tizot A, Raimbaud E, Lockhart B, Lestage P, Goldstein S.

J Med Chem. 2000 Jun 1;43(11):2165-75.

PMID:
10841795
[PubMed - indexed for MEDLINE]
10.

Radical trapping and inhibition of iron-dependent CNS damage by cyclic nitrone spin traps.

Thomas CE, Ohlweiler DF, Taylor VL, Schmidt CJ.

J Neurochem. 1997 Mar;68(3):1173-82.

PMID:
9048764
[PubMed - indexed for MEDLINE]
11.

Characterization of the radical trapping activity of a novel series of cyclic nitrone spin traps.

Thomas CE, Ohlweiler DF, Carr AA, Nieduzak TR, Hay DA, Adams G, Vaz R, Bernotas RC.

J Biol Chem. 1996 Feb 9;271(6):3097-104.

PMID:
8621707
[PubMed - indexed for MEDLINE]
Free Article
12.

Increase of antioxidative potential by tert-butylhydroquinone protects against cell death associated with 6-hydroxydopamine-induced oxidative stress in neuroblastoma SH-SY5Y cells.

Hara H, Ohta M, Ohta K, Kuno S, Adachi T.

Brain Res Mol Brain Res. 2003 Nov 26;119(2):125-31.

PMID:
14625079
[PubMed - indexed for MEDLINE]
13.

The spin trapping agent PBN stimulates H2 O2 -induced Erk and Src kinase activity in human neuroblastoma cells.

Kelicen P, Cantuti-Castelvetri I, Pekiner C, Paulson KE.

Neuroreport. 2002 Jun 12;13(8):1057-61.

PMID:
12060808
[PubMed - indexed for MEDLINE]
14.

Nitrones as neuroprotectants and antiaging drugs.

Floyd RA, Hensley K, Forster MJ, Kelleher-Anderson JA, Wood PL.

Ann N Y Acad Sci. 2002 Apr;959:321-9. Review.

PMID:
11976206
[PubMed - indexed for MEDLINE]
15.

Nitrones as therapeutics.

Floyd RA, Kopke RD, Choi CH, Foster SB, Doblas S, Towner RA.

Free Radic Biol Med. 2008 Nov 15;45(10):1361-74. doi: 10.1016/j.freeradbiomed.2008.08.017. Epub 2008 Aug 29. Review.

PMID:
18793715
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Effects of phenyl N-tert-butyl nitrone and its derivatives on the early phase of hepatocarcinogenesis in rats fed a choline-deficient, L-amino acid-defined diet.

Nakae D, Kishida H, Enami T, Konishi Y, Hensley KL, Floyd RA, Kotake Y.

Cancer Sci. 2003 Jan;94(1):26-31.

PMID:
12708470
[PubMed - indexed for MEDLINE]
17.

Inhibition of 6-hydroxydopamine-induced oxidative damage by 4,5-dihydro-3H-2-benzazepine N-oxides.

Soto-Otero R, Méndez-Alvarez E, Sánchez-Iglesias S, Zubkov FI, Voskressensky LG, Varlamov AV, de Candia M, Altomare C.

Biochem Pharmacol. 2008 Apr 1;75(7):1526-37. doi: 10.1016/j.bcp.2007.12.010. Epub 2008 Jan 5.

PMID:
18275937
[PubMed - indexed for MEDLINE]
18.

The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia.

Banno M, Mizuno T, Kato H, Zhang G, Kawanokuchi J, Wang J, Kuno R, Jin S, Takeuchi H, Suzumura A.

Neuropharmacology. 2005 Feb;48(2):283-90. Epub 2004 Dec 24.

PMID:
15695167
[PubMed - indexed for MEDLINE]
19.

Mitochondrial medicine: neuroprotection and life extension by the new amphiphilic nitrone LPBNAH acting as a highly potent antioxidant agent.

Poeggeler B, Durand G, Polidori A, Pappolla MA, Vega-Naredo I, Coto-Montes A, Böker J, Hardeland R, Pucci B.

J Neurochem. 2005 Nov;95(4):962-73. Epub 2005 Aug 31.

PMID:
16135084
[PubMed - indexed for MEDLINE]
20.

Treatment with the spin-trap agent alpha-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons.

Karlsson J, Emgârd M, Rosenblad C, Brundin P.

Brain Res. 1998 Sep 14;805(1-2):155-68.

PMID:
9733957
[PubMed - indexed for MEDLINE]

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