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Results: 1 to 20 of 157

1.

Distinct patterns of constitutive phosphodiesterase activity in mouse sinoatrial node and atrial myocardium.

Hua R, Adamczyk A, Robbins C, Ray G, Rose RA.

PLoS One. 2012;7(10):e47652. doi: 10.1371/journal.pone.0047652. Epub 2012 Oct 15.

PMID:
23077656
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Phosphodiesterases do not limit beta1-adrenoceptor-mediated sinoatrial tachycardia: evidence with PDE3 and PDE4 in rabbits and PDE1-5 in rats.

Kaumann AJ, Galindo-Tovar A, Escudero E, Vargas ML.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Nov;380(5):421-30. doi: 10.1007/s00210-009-0445-5. Epub 2009 Aug 20.

PMID:
19693491
[PubMed - indexed for MEDLINE]
3.

Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac beta(1)-adrenoceptors.

Galindo-Tovar A, Kaumann AJ.

Br J Pharmacol. 2008 Feb;153(4):710-20. Epub 2007 Dec 17.

PMID:
18084319
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases.

Leroy J, Abi-Gerges A, Nikolaev VO, Richter W, Lechêne P, Mazet JL, Conti M, Fischmeister R, Vandecasteele G.

Circ Res. 2008 May 9;102(9):1091-100. doi: 10.1161/CIRCRESAHA.107.167817. Epub 2008 Mar 27.

PMID:
18369156
[PubMed - indexed for MEDLINE]
Free Article
5.

Characterization of the cyclic nucleotide phosphodiesterase subtypes involved in the regulation of the L-type Ca2+ current in rat ventricular myocytes.

Verde I, Vandecasteele G, Lezoualc'h F, Fischmeister R.

Br J Pharmacol. 1999 May;127(1):65-74.

PMID:
10369457
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart.

Christ T, Galindo-Tovar A, Thoms M, Ravens U, Kaumann AJ.

Br J Pharmacol. 2009 Jan;156(1):62-83. doi: 10.1111/j.1476-5381.2008.00015.x.

PMID:
19133992
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Role of cyclic nucleotide phosphodiesterase isoforms in cAMP compartmentation following beta2-adrenergic stimulation of ICa,L in frog ventricular myocytes.

Jurevicius J, Skeberdis VA, Fischmeister R.

J Physiol. 2003 Aug 15;551(Pt 1):239-52. Epub 2003 Jun 18.

PMID:
12815180
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes.

Vandecasteele G, Verde I, Rücker-Martin C, Donzeau-Gouge P, Fischmeister R.

J Physiol. 2001 Jun 1;533(Pt 2):329-40.

PMID:
11389195
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes.

Rivet-Bastide M, Vandecasteele G, Hatem S, Verde I, Bénardeau A, Mercadier JJ, Fischmeister R.

J Clin Invest. 1997 Jun 1;99(11):2710-8.

PMID:
9169501
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes.

Mika D, Bobin P, Pomérance M, Lechêne P, Westenbroek RE, Catterall WA, Vandecasteele G, Leroy J, Fischmeister R.

Cardiovasc Res. 2013 Nov 1;100(2):336-46. doi: 10.1093/cvr/cvt193. Epub 2013 Aug 9.

PMID:
23933582
[PubMed - indexed for MEDLINE]
12.

The natriuretic peptides BNP and CNP increase heart rate and electrical conduction by stimulating ionic currents in the sinoatrial node and atrial myocardium following activation of guanylyl cyclase-linked natriuretic peptide receptors.

Springer J, Azer J, Hua R, Robbins C, Adamczyk A, McBoyle S, Bissell MB, Rose RA.

J Mol Cell Cardiol. 2012 May;52(5):1122-34. doi: 10.1016/j.yjmcc.2012.01.018. Epub 2012 Feb 1.

PMID:
22326431
[PubMed - indexed for MEDLINE]
13.

PI3Kgamma is required for PDE4, not PDE3, activity in subcellular microdomains containing the sarcoplasmic reticular calcium ATPase in cardiomyocytes.

Kerfant BG, Zhao D, Lorenzen-Schmidt I, Wilson LS, Cai S, Chen SR, Maurice DH, Backx PH.

Circ Res. 2007 Aug 17;101(4):400-8. Epub 2007 Jul 5.

PMID:
17615371
[PubMed - indexed for MEDLINE]
Free Article
14.

Cyclic adenosine monophosphate phosphodiesterase type 4 protects against atrial arrhythmias.

Molina CE, Leroy J, Richter W, Xie M, Scheitrum C, Lee IO, Maack C, Rucker-Martin C, Donzeau-Gouge P, Verde I, Llach A, Hove-Madsen L, Conti M, Vandecasteele G, Fischmeister R.

J Am Coll Cardiol. 2012 Jun 12;59(24):2182-90. doi: 10.1016/j.jacc.2012.01.060.

PMID:
22676938
[PubMed - indexed for MEDLINE]
Free Article
15.

Regulation by phosphodiesterase isoforms of protein kinase A-mediated attenuation of myocardial protein kinase D activation.

Haworth RS, Cuello F, Avkiran M.

Basic Res Cardiol. 2011 Jan;106(1):51-63. doi: 10.1007/s00395-010-0116-1. Epub 2010 Aug 20.

PMID:
20725733
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Function of cardiac beta1- and beta2-adrenoceptors of newborn piglets: role of phosphodiesterases PDE3 and PDE4.

Galindo-Tovar A, Vargas ML, Kaumann AJ.

Eur J Pharmacol. 2010 Jul 25;638(1-3):99-107. doi: 10.1016/j.ejphar.2010.04.013. Epub 2010 Apr 18.

PMID:
20406625
[PubMed - indexed for MEDLINE]
17.

5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles.

Afzal F, Andressen KW, Mørk HK, Aronsen JM, Sjaastad I, Dahl CP, Skomedal T, Levy FO, Osnes JB, Qvigstad E.

Br J Pharmacol. 2008 Dec;155(7):1005-14. doi: 10.1038/bjp.2008.339. Epub 2008 Sep 1.

PMID:
18846035
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

PDE type-4 inhibition increases L-type Ca(2+) currents, action potential firing, and quantal size of exocytosis in mouse chromaffin cells.

Marcantoni A, Carabelli V, Vandael DH, Comunanza V, Carbone E.

Pflugers Arch. 2009 Mar;457(5):1093-110. doi: 10.1007/s00424-008-0584-4. Epub 2008 Sep 9.

PMID:
18779976
[PubMed - indexed for MEDLINE]
19.

PDE3 and PDE4 isozyme-selective inhibitors are both required for synergistic activation of brown adipose tissue.

Kraynik SM, Miyaoka RS, Beavo JA.

Mol Pharmacol. 2013 Jun;83(6):1155-65. doi: 10.1124/mol.112.084145. Epub 2013 Mar 14.

PMID:
23493317
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans.

Adderley SP, Dufaux EA, Sridharan M, Bowles EA, Hanson MS, Stephenson AH, Ellsworth ML, Sprague RS.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1617-24. doi: 10.1152/ajpheart.01226.2008. Epub 2009 Feb 27.

PMID:
19252089
[PubMed - indexed for MEDLINE]
Free PMC Article

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