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Items: 1 to 20 of 85


The retinoblastoma protein is essential for survival of postmitotic neurons.

Andrusiak MG, Vandenbosch R, Park DS, Slack RS.

J Neurosci. 2012 Oct 17;32(42):14809-14. doi: 10.1523/JNEUROSCI.1912-12.2012.


Cell cycle regulators in neural stem cells and postmitotic neurons.

Yoshikawa K.

Neurosci Res. 2000 May;37(1):1-14. Review.


Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity.

Callaghan DA, Dong L, Callaghan SM, Hou YX, Dagnino L, Slack RS.

Dev Biol. 1999 Mar 15;207(2):257-70.


In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice.

Yu Y, Weber T, Yamashita T, Liu Z, Valentine MB, Cox BC, Zuo J.

J Neurosci. 2010 Apr 28;30(17):5927-36. doi: 10.1523/JNEUROSCI.5989-09.2010.


A critical temporal requirement for the retinoblastoma protein family during neuronal determination.

Slack RS, El-Bizri H, Wong J, Belliveau DJ, Miller FD.

J Cell Biol. 1998 Mar 23;140(6):1497-509.


Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma.

Chen D, Livne-bar I, Vanderluit JL, Slack RS, Agochiya M, Bremner R.

Cancer Cell. 2004 Jun;5(6):539-51.


LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence.

Andrusiak MG, Vandenbosch R, Dick FA, Park DS, Slack RS.

Cell Cycle. 2013 May 1;12(9):1416-23. doi: 10.4161/cc.24527. Epub 2013 Apr 9.


Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage.

Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, Shelanski ML, Geller HM, Greene LA.

J Neurosci. 2000 May 1;20(9):3104-14.


Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.

Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, Jacks T.

Genes Dev. 2000 Dec 1;14(23):3037-50.


Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells.

Smith RA, Walker T, Xie X, Hou ST.

Brain Res Mol Brain Res. 2003 Aug 19;116(1-2):70-9.


Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.

Lieman JH, Worley LA, Harbour JW.

J Biol Chem. 2005 Mar 18;280(11):10484-90. Epub 2005 Jan 7.


Neuronal apoptosis at the G1/S cell cycle checkpoint.

Liu DX, Greene LA.

Cell Tissue Res. 2001 Aug;305(2):217-28. Review.


Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation.

Lee EY, Hu N, Yuan SS, Cox LA, Bradley A, Lee WH, Herrup K.

Genes Dev. 1994 Sep 1;8(17):2008-21.


Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.

Lipinski MM, Macleod KF, Williams BO, Mullaney TL, Crowley D, Jacks T.

EMBO J. 2001 Jul 2;20(13):3402-13.


Induction and modulation of cerebellar granule neuron death by E2F-1.

O'Hare MJ, Hou ST, Morris EJ, Cregan SP, Xu Q, Slack RS, Park DS.

J Biol Chem. 2000 Aug 18;275(33):25358-64.


The chemokine CXCL12 promotes survival of postmitotic neurons by regulating Rb protein.

Khan MZ, Brandimarti R, Shimizu S, Nicolai J, Crowe E, Meucci O.

Cell Death Differ. 2008 Oct;15(10):1663-72. doi: 10.1038/cdd.2008.95. Epub 2008 Jun 27.


Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.

McClellan KA, Ruzhynsky VA, Douda DN, Vanderluit JL, Ferguson KL, Chen D, Bremner R, Park DS, Leone G, Slack RS.

Mol Cell Biol. 2007 Jul;27(13):4825-43. Epub 2007 Apr 23.


RB, the conductor that orchestrates life, death and differentiation.

Khidr L, Chen PL.

Oncogene. 2006 Aug 28;25(38):5210-9. Review.

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