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Items: 1 to 20 of 82

1.

RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice.

Thomas RR, Khan SM, Smigrodzki RM, Onyango IG, Dennis J, Khan OM, Portelli FR, Bennett JP Jr.

Aging (Albany NY). 2012 Sep;4(9):620-35.

2.

Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.

Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr.

Mitochondrion. 2011 Jan;11(1):108-18. doi: 10.1016/j.mito.2010.08.004. Epub 2010 Aug 18.

3.

Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice.

Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H.

J Neurosci. 2008 Aug 20;28(34):8624-34. doi: 10.1523/JNEUROSCI.1957-08.2008.

4.

Recombinant mitochondrial transcription factor A protein inhibits nuclear factor of activated T cells signaling and attenuates pathological hypertrophy of cardiac myocytes.

Fujino T, Ide T, Yoshida M, Onitsuka K, Tanaka A, Hata Y, Nishida M, Takehara T, Kanemaru T, Kitajima N, Takazaki S, Kurose H, Kang D, Sunagawa K.

Mitochondrion. 2012 Jul;12(4):449-58. doi: 10.1016/j.mito.2012.06.002. Epub 2012 Jun 16.

PMID:
22709542
5.

Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles.

Garnier A, Fortin D, Deloménie C, Momken I, Veksler V, Ventura-Clapier R.

J Physiol. 2003 Sep 1;551(Pt 2):491-501. Epub 2003 Jun 24.

6.

Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes.

Hao J, Shen W, Yu G, Jia H, Li X, Feng Z, Wang Y, Weber P, Wertz K, Sharman E, Liu J.

J Nutr Biochem. 2010 Jul;21(7):634-44. doi: 10.1016/j.jnutbio.2009.03.012. Epub 2009 Jul 2.

PMID:
19576748
7.
8.

Nuclear and mitochondrial genome responses in HeLa cells treated with inhibitors of mitochondrial DNA expression.

Piechota J, Szczesny R, Wolanin K, Chlebowski A, Bartnik E.

Acta Biochim Pol. 2006;53(3):485-95. Epub 2006 Sep 2.

9.

Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri.

Hartmann N, Reichwald K, Wittig I, Dröse S, Schmeisser S, Lück C, Hahn C, Graf M, Gausmann U, Terzibasi E, Cellerino A, Ristow M, Brandt U, Platzer M, Englert C.

Aging Cell. 2011 Oct;10(5):824-31. doi: 10.1111/j.1474-9726.2011.00723.x. Epub 2011 Jun 27.

10.
11.

Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells.

Iyer S, Bergquist K, Young K, Gnaiger E, Rao RR, Bennett JP Jr.

Hum Gene Ther. 2012 Jun;23(6):647-57. doi: 10.1089/hum.2011.177. Epub 2012 Apr 17.

12.

Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders.

Poon HF, Farr SA, Thongboonkerd V, Lynn BC, Banks WA, Morley JE, Klein JB, Butterfield DA.

Neurochem Int. 2005 Jan;46(2):159-68.

PMID:
15627516
13.

The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle.

Adhihetty PJ, Uguccioni G, Leick L, Hidalgo J, Pilegaard H, Hood DA.

Am J Physiol Cell Physiol. 2009 Jul;297(1):C217-25. doi: 10.1152/ajpcell.00070.2009. Epub 2009 May 13.

14.
15.

Generation and bioenergetic analysis of cybrids containing mitochondrial DNA from mouse skeletal muscle during aging.

Li Y, Li HZ, Hu P, Deng J, Banoei MM, Sharma LK, Bai Y.

Nucleic Acids Res. 2010 Apr;38(6):1913-21. doi: 10.1093/nar/gkp1162. Epub 2009 Dec 18.

16.

Compensatory responses of protein import and transcription factor expression in mitochondrial DNA defects.

Joseph AM, Rungi AA, Robinson BH, Hood DA.

Am J Physiol Cell Physiol. 2004 Apr;286(4):C867-75. Epub 2003 Dec 3.

17.

Deficiency of the human mitochondrial transcription factor h-mtTFA in infantile mitochondrial myopathy is associated with mtDNA depletion.

Poulton J, Morten K, Freeman-Emmerson C, Potter C, Sewry C, Dubowitz V, Kidd H, Stephenson J, Whitehouse W, Hansen FJ, et al.

Hum Mol Genet. 1994 Oct;3(10):1763-9.

PMID:
7849699
18.

Aberrant cell proliferation by enhanced mitochondrial biogenesis via mtTFA in arsenical skin cancers.

Lee CH, Wu SB, Hong CH, Liao WT, Wu CY, Chen GS, Wei YH, Yu HS.

Am J Pathol. 2011 May;178(5):2066-76. doi: 10.1016/j.ajpath.2011.01.056.

19.

Mitochondrial DNA damage and the aging process: facts and imaginations.

Wiesner RJ, Zsurka G, Kunz WS.

Free Radic Res. 2006 Dec;40(12):1284-94. Review.

PMID:
17090418
20.
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