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Items: 1 to 20 of 84

1.

Hypoxia inducible factors-mediated inhibition of cancer by GM-CSF: a mathematical model.

Chen D, Roda JM, Marsh CB, Eubank TD, Friedman A.

Bull Math Biol. 2012 Nov;74(11):2752-77. doi: 10.1007/s11538-012-9776-3. Epub 2012 Oct 17.

2.

Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis.

Roda JM, Sumner LA, Evans R, Phillips GS, Marsh CB, Eubank TD.

J Immunol. 2011 Aug 15;187(4):1970-6. doi: 10.4049/jimmunol.1100841. Epub 2011 Jul 15.

3.

Stabilization of HIF-2α induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.

Roda JM, Wang Y, Sumner LA, Phillips GS, Marsh CB, Eubank TD.

J Immunol. 2012 Sep 15;189(6):3168-77. doi: 10.4049/jimmunol.1103817. Epub 2012 Aug 6.

4.

Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes.

Eubank TD, Roda JM, Liu H, O'Neil T, Marsh CB.

Blood. 2011 Jan 6;117(1):323-32. doi: 10.1182/blood-2010-01-261792. Epub 2010 Oct 15.

5.

Modeling the inhibition of breast cancer growth by GM-CSF.

Szomolay B, Eubank TD, Roberts RD, Marsh CB, Friedman A.

J Theor Biol. 2012 Jun 21;303:141-51. doi: 10.1016/j.jtbi.2012.03.024. Epub 2012 Mar 28.

PMID:
22763136
6.

Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.

Spinella F, Rosanò L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, Bagnato A.

PLoS One. 2010 Jun 21;5(6):e11241. doi: 10.1371/journal.pone.0011241.

8.

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.

Puppo M, Battaglia F, Ottaviano C, Delfino S, Ribatti D, Varesio L, Bosco MC.

Mol Cancer Ther. 2008 Jul;7(7):1974-84. doi: 10.1158/1535-7163.MCT-07-2059.

10.

Anticancer imidazoacridinone C-1311 inhibits hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and angiogenesis.

Paradziej-Łukowicz J, Skwarska A, Peszyńska-Sularz G, Brillowska-Dąbrowska A, Konopa J.

Cancer Biol Ther. 2011 Oct 1;12(7):586-97. Epub 2011 Oct 1.

PMID:
21775820
11.

HIF-1alpha and HIF-2alpha are differentially regulated in vivo in neuroblastoma: high HIF-1alpha correlates negatively to advanced clinical stage and tumor vascularization.

Noguera R, Fredlund E, Piqueras M, Pietras A, Beckman S, Navarro S, Påhlman S.

Clin Cancer Res. 2009 Dec 1;15(23):7130-6. doi: 10.1158/1078-0432.CCR-09-0223. Epub 2009 Nov 10.

12.

Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation.

Stoeltzing O, McCarty MF, Wey JS, Fan F, Liu W, Belcheva A, Bucana CD, Semenza GL, Ellis LM.

J Natl Cancer Inst. 2004 Jun 16;96(12):946-56.

13.

Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma.

Sivridis E, Giatromanolaki A, Gatter KC, Harris AL, Koukourakis MI; Tumor and Angiogenesis Research Group.

Cancer. 2002 Sep 1;95(5):1055-63.

15.

Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment.

Burkitt K, Chun SY, Dang DT, Dang LH.

Mol Cancer Ther. 2009 May;8(5):1148-56. doi: 10.1158/1535-7163.MCT-08-0944. Epub 2009 May 12.

18.

Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.

Shinojima T, Oya M, Takayanagi A, Mizuno R, Shimizu N, Murai M.

Carcinogenesis. 2007 Mar;28(3):529-36. Epub 2006 Aug 18.

19.
20.

Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages.

Eubank TD, Roberts RD, Khan M, Curry JM, Nuovo GJ, Kuppusamy P, Marsh CB.

Cancer Res. 2009 Mar 1;69(5):2133-40. doi: 10.1158/0008-5472.CAN-08-1405. Epub 2009 Feb 17.

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