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Results: 1 to 20 of 90

1.

Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry.

Chetty PS, Ohshiro M, Saito H, Dhanasekaran P, Lund-Katz S, Mayne L, Englander W, Phillips MC.

Biochemistry. 2012 Nov 6;51(44):8993-9001. doi: 10.1021/bi300926j. Epub 2012 Oct 24.

PMID:
23066790
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Apolipoprotein A-I helical structure and stability in discoidal high-density lipoprotein (HDL) particles by hydrogen exchange and mass spectrometry.

Sevugan Chetty P, Mayne L, Kan ZY, Lund-Katz S, Englander SW, Phillips MC.

Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11687-92. doi: 10.1073/pnas.1209305109. Epub 2012 Jun 27.

PMID:
22745166
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Dual role of an N-terminal amyloidogenic mutation in apolipoprotein A-I: destabilization of helix bundle and enhancement of fibril formation.

Adachi E, Nakajima H, Mizuguchi C, Dhanasekaran P, Kawashima H, Nagao K, Akaji K, Lund-Katz S, Phillips MC, Saito H.

J Biol Chem. 2013 Jan 25;288(4):2848-56. doi: 10.1074/jbc.M112.428052. Epub 2012 Dec 11.

PMID:
23233678
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry.

Chetty PS, Mayne L, Lund-Katz S, Stranz D, Englander SW, Phillips MC.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19005-10. doi: 10.1073/pnas.0909708106. Epub 2009 Oct 22.

PMID:
19850866
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The crystal structure of the C-terminal truncated apolipoprotein A-I sheds new light on amyloid formation by the N-terminal fragment.

Gursky O, Mei X, Atkinson D.

Biochemistry. 2012 Jan 10;51(1):10-8. doi: 10.1021/bi2017014. Epub 2011 Dec 29. Review.

PMID:
22229410
[PubMed - indexed for MEDLINE]
6.

Structural and functional consequences of the Milano mutation (R173C) in human apolipoprotein A-I.

Alexander ET, Tanaka M, Kono M, Saito H, Rader DJ, Phillips MC.

J Lipid Res. 2009 Jul;50(7):1409-19. doi: 10.1194/jlr.M800578-JLR200. Epub 2009 Mar 24.

PMID:
19318685
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of apolipoprotein A-I.

Tanaka M, Dhanasekaran P, Nguyen D, Ohta S, Lund-Katz S, Phillips MC, Saito H.

Biochemistry. 2006 Aug 29;45(34):10351-8.

PMID:
16922511
[PubMed - indexed for MEDLINE]
8.

Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I.

Tanaka M, Dhanasekaran P, Nguyen D, Nickel M, Takechi Y, Lund-Katz S, Phillips MC, Saito H.

Biochim Biophys Acta. 2011 Jan;1811(1):25-30. doi: 10.1016/j.bbalip.2010.10.003. Epub 2010 Oct 30.

PMID:
21040803
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties.

Zhu X, Wu G, Zeng W, Xue H, Chen B.

J Lipid Res. 2005 Jun;46(6):1303-11. Epub 2005 Apr 1.

PMID:
15805548
[PubMed - indexed for MEDLINE]
Free Article
10.

Interaction between the N- and C-terminal domains modulates the stability and lipid binding of apolipoprotein A-I.

Koyama M, Tanaka M, Dhanasekaran P, Lund-Katz S, Phillips MC, Saito H.

Biochemistry. 2009 Mar 24;48(11):2529-37. doi: 10.1021/bi802317v.

PMID:
19239199
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Dissecting interdomain communication within cAPK regulatory subunit type IIbeta using enhanced amide hydrogen/deuterium exchange mass spectrometry (DXMS).

Zawadzki KM, Hamuro Y, Kim JS, Garrod S, Stranz DD, Taylor SS, Woods VL Jr.

Protein Sci. 2003 Sep;12(9):1980-90.

PMID:
12930997
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Secondary structure changes in ApoA-I Milano (R173C) are not accompanied by a decrease in protein stability or solubility.

Petrlova J, Dalla-Riva J, Mörgelin M, Lindahl M, Krupinska E, Stenkula KG, Voss JC, Lagerstedt JO.

PLoS One. 2014 Apr 22;9(4):e96150. doi: 10.1371/journal.pone.0096150. eCollection 2014.

PMID:
24755625
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I.

Tanaka M, Koyama M, Dhanasekaran P, Nguyen D, Nickel M, Lund-Katz S, Saito H, Phillips MC.

Biochemistry. 2008 Feb 19;47(7):2172-80. doi: 10.1021/bi702332b. Epub 2008 Jan 19.

PMID:
18205410
[PubMed - indexed for MEDLINE]
15.

Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry.

Chetty PS, Nguyen D, Nickel M, Lund-Katz S, Mayne L, Englander SW, Phillips MC.

J Lipid Res. 2013 Jun;54(6):1589-97. doi: 10.1194/jlr.M034785. Epub 2013 Apr 10.

PMID:
23580759
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Conformational flexibility of the N-terminal domain of apolipoprotein a-I bound to spherical lipid particles.

Kono M, Okumura Y, Tanaka M, Nguyen D, Dhanasekaran P, Lund-Katz S, Phillips MC, Saito H.

Biochemistry. 2008 Oct 28;47(43):11340-7. doi: 10.1021/bi801503r. Epub 2008 Oct 2.

PMID:
18831538
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis.

Wilson LM, Mok YF, Binger KJ, Griffin MD, Mertens HD, Lin F, Wade JD, Gooley PR, Howlett GJ.

J Mol Biol. 2007 Mar 9;366(5):1639-51. Epub 2006 Dec 21.

PMID:
17217959
[PubMed - indexed for MEDLINE]
18.

The new apolipoprotein A-I variant leu(174) --> Ser causes hereditary cardiac amyloidosis, and the amyloid fibrils are constituted by the 93-residue N-terminal polypeptide.

Obici L, Bellotti V, Mangione P, Stoppini M, Arbustini E, Verga L, Zorzoli I, Anesi E, Zanotti G, Campana C, Viganò M, Merlini G.

Am J Pathol. 1999 Sep;155(3):695-702.

PMID:
10487826
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Hydrogen/deuterium exchange mass spectrometry with top-down electron capture dissociation for characterizing structural transitions of a 17 kDa protein.

Pan J, Han J, Borchers CH, Konermann L.

J Am Chem Soc. 2009 Sep 9;131(35):12801-8. doi: 10.1021/ja904379w.

PMID:
19670873
[PubMed - indexed for MEDLINE]
20.

Molecular belt models for the apolipoprotein A-I Paris and Milano mutations.

Klon AE, Jones MK, Segrest JP, Harvey SC.

Biophys J. 2000 Sep;79(3):1679-85.

PMID:
10969027
[PubMed - indexed for MEDLINE]
Free PMC Article
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