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Results: 1 to 20 of 110

1.

Therapeutic targets in the ASK1-dependent stress signaling pathways.

Hayakawa R, Hayakawa T, Takeda K, Ichijo H.

Proc Jpn Acad Ser B Phys Biol Sci. 2012;88(8):434-53. Review.

PMID:
23060232
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, Ichijo H.

Antioxid Redox Signal. 2002 Jun;4(3):415-25. Review.

PMID:
12215209
[PubMed - indexed for MEDLINE]
3.

The ASK1-MAP kinase cascades in mammalian stress response.

Matsukawa J, Matsuzawa A, Takeda K, Ichijo H.

J Biochem. 2004 Sep;136(3):261-5. Review.

PMID:
15598880
[PubMed - indexed for MEDLINE]
Free Article
4.

Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling.

Shiizaki S, Naguro I, Ichijo H.

Adv Biol Regul. 2013 Jan;53(1):135-44. doi: 10.1016/j.jbior.2012.09.006. Epub 2012 Sep 13. Review.

PMID:
23031789
[PubMed - indexed for MEDLINE]
5.

Pathophysiological roles of ASK1-MAP kinase signaling pathways.

Nagai H, Noguchi T, Takeda K, Ichijo H.

J Biochem Mol Biol. 2007 Jan 31;40(1):1-6. Review.

PMID:
17244475
[PubMed - indexed for MEDLINE]
Free Article
6.

Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.

Kim I, Shu CW, Xu W, Shiau CW, Grant D, Vasile S, Cosford ND, Reed JC.

J Biol Chem. 2009 Jan 16;284(3):1593-603. doi: 10.1074/jbc.M807308200. Epub 2008 Nov 12.

PMID:
19004820
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

Nakagawa H, Hirata Y, Takeda K, Hayakawa Y, Sato T, Kinoshita H, Sakamoto K, Nakata W, Hikiba Y, Omata M, Yoshida H, Koike K, Ichijo H, Maeda S.

Hepatology. 2011 Jul;54(1):185-95. doi: 10.1002/hep.24357.

PMID:
21488081
[PubMed - indexed for MEDLINE]
8.

Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling.

Matsuzawa A, Ichijo H.

Biochim Biophys Acta. 2008 Nov;1780(11):1325-36. doi: 10.1016/j.bbagen.2007.12.011. Epub 2008 Jan 16. Review.

PMID:
18206122
[PubMed - indexed for MEDLINE]
9.

Apoptosis signal-regulating kinase 1 in stress and immune response.

Takeda K, Noguchi T, Naguro I, Ichijo H.

Annu Rev Pharmacol Toxicol. 2008;48:199-225. Review.

PMID:
17883330
[PubMed - indexed for MEDLINE]
10.

The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases.

Sekine Y, Takeda K, Ichijo H.

Curr Mol Med. 2006 Feb;6(1):87-97. Review.

PMID:
16472116
[PubMed - indexed for MEDLINE]
11.

Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation.

Nakagawa H, Maeda S, Hikiba Y, Ohmae T, Shibata W, Yanai A, Sakamoto K, Ogura K, Noguchi T, Karin M, Ichijo H, Omata M.

Gastroenterology. 2008 Oct;135(4):1311-21. doi: 10.1053/j.gastro.2008.07.006. Epub 2008 Jul 9.

PMID:
18700144
[PubMed - indexed for MEDLINE]
12.

[ASK1-MAP kinase signaling pathway as a therapeutic target for human diseases].

Fujisawa T, Ichijo H.

Nihon Rinsho. 2014 May;72(5):957-65. Review. Japanese.

PMID:
24912301
[PubMed - indexed for MEDLINE]
13.

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.

Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H.

EMBO Rep. 2001 Mar;2(3):222-8.

PMID:
11266364
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

Niso-Santano M, González-Polo RA, Bravo-San Pedro JM, Gómez-Sánchez R, Lastres-Becker I, Ortiz-Ortiz MA, Soler G, Morán JM, Cuadrado A, Fuentes JM; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED).

Free Radic Biol Med. 2010 May 15;48(10):1370-81. doi: 10.1016/j.freeradbiomed.2010.02.024. Epub 2010 Mar 2.

PMID:
20202476
[PubMed - indexed for MEDLINE]
15.

Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation.

Li X, Zhang R, Luo D, Park SJ, Wang Q, Kim Y, Min W.

J Biol Chem. 2005 Apr 15;280(15):15061-70. Epub 2005 Feb 8.

PMID:
15701637
[PubMed - indexed for MEDLINE]
Free Article
16.

Targeting ASK1 in ER stress-related neurodegenerative diseases.

Homma K, Katagiri K, Nishitoh H, Ichijo H.

Expert Opin Ther Targets. 2009 Jun;13(6):653-64. doi: 10.1517/14728220902980249. Review.

PMID:
19456270
[PubMed - indexed for MEDLINE]
18.

Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.

Yu Y, Richardson DR.

J Biol Chem. 2011 Apr 29;286(17):15413-27. doi: 10.1074/jbc.M111.225946. Epub 2011 Mar 5.

PMID:
21378396
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Roles of MAPKKK ASK1 in stress-induced cell death.

Takeda K, Matsuzawa A, Nishitoh H, Ichijo H.

Cell Struct Funct. 2003 Feb;28(1):23-9. Review.

PMID:
12655147
[PubMed - indexed for MEDLINE]
Free Article
20.

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury.

Ben Mkaddem S, Pedruzzi E, Werts C, Coant N, Bens M, Cluzeaud F, Goujon JM, Ogier-Denis E, Vandewalle A.

Cell Death Differ. 2010 Sep;17(9):1474-85. doi: 10.1038/cdd.2010.26. Epub 2010 Mar 12.

PMID:
20224597
[PubMed - indexed for MEDLINE]
Free Article

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