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Items: 1 to 20 of 164

1.

Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD.

Ubhi BK, Cheng KK, Dong J, Janowitz T, Jodrell D, Tal-Singer R, MacNee W, Lomas DA, Riley JH, Griffin JL, Connor SC.

Mol Biosyst. 2012 Oct 30;8(12):3125-33. doi: 10.1039/c2mb25194a.

PMID:
23051772
2.

Metabolic profiling detects biomarkers of protein degradation in COPD patients.

Ubhi BK, Riley JH, Shaw PA, Lomas DA, Tal-Singer R, MacNee W, Griffin JL, Connor SC.

Eur Respir J. 2012 Aug;40(2):345-55. doi: 10.1183/09031936.00112411. Epub 2011 Dec 19.

3.

Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease.

Albert P, Agusti A, Edwards L, Tal-Singer R, Yates J, Bakke P, Celli BR, Coxson HO, Crim C, Lomas DA, Macnee W, Miller B, Rennard S, Silverman EK, Vestbo J, Wouters E, Calverley P.

Thorax. 2012 Aug;67(8):701-8. doi: 10.1136/thoraxjnl-2011-201458. Epub 2012 Jun 13.

PMID:
22696176
4.

Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study.

Miniati M, Monti S, Basta G, Cocci F, Fornai E, Bottai M.

Respir Res. 2011 Mar 30;12:37. doi: 10.1186/1465-9921-12-37.

5.

Vitamin D, vitamin D binding protein, lung function and structure in COPD.

Berg I, Hanson C, Sayles H, Romberger D, Nelson A, Meza J, Miller B, Wouters EF, Macnee W, Rutten EP, Romme EA, Vestbo J, Edwards L, Rennard S.

Respir Med. 2013 Oct;107(10):1578-88. doi: 10.1016/j.rmed.2013.05.010. Epub 2013 Jul 1.

6.

Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE).

Vestbo J, Anderson W, Coxson HO, Crim C, Dawber F, Edwards L, Hagan G, Knobil K, Lomas DA, MacNee W, Silverman EK, Tal-Singer R; ECLIPSE investigators.

Eur Respir J. 2008 Apr;31(4):869-73. doi: 10.1183/09031936.00111707. Epub 2008 Jan 23.

7.

Circulating levels of soluble Fas ligand in cachexic patients with COPD are higher than those in non-cachexic patients with COPD.

Takabatake N, Arao T, Sata M, Inoue S, Abe S, Shibata Y, Kubota I.

Intern Med. 2005 Nov;44(11):1137-43.

8.

Emphysematous phenotype is an independent predictor for frequent exacerbation of COPD.

Oh YM, Sheen SS, Park JH, Jin UR, Yoo JW, Seo JB, Yoo KH, Lee JH, Kim TH, Lim SY, Yoon HI, Lee JS, Lee SD.

Int J Tuberc Lung Dis. 2014 Dec;18(12):1407-14. doi: 10.5588/ijtld.14.0205.

PMID:
25517804
9.

Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.

Wan ES, Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Won S, Lange C, Pillai SG, Anderson WH, Kong X, Lomas DA, Bakke PS, Gulsvik A, Regan EA, Murphy JR, Make BJ, Crapo JD, Wouters EF, Celli BR, Silverman EK, DeMeo DL; Evaluation of Chronic Obstructive Pulmonary Disease Longitudinally to Identify Predictive Surrogate End-Points (ECLIPSE); Norway-Bergen cohort; National Emphysema Treatment Trial; COPD Gene investigators.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):304-10. doi: 10.1165/rcmb.2010-0294OC. Epub 2010 Oct 29.

10.

The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study.

Coxson HO, Dirksen A, Edwards LD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Crim C, Duvoix A, Fauerbach PN, Lomas DA, Macnee W, Mayer RJ, Miller BE, Müller NL, Rennard SI, Silverman EK, Tal-Singer R, Wouters EF, Vestbo J; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators.

Lancet Respir Med. 2013 Apr;1(2):129-36. doi: 10.1016/S2213-2600(13)70006-7. Epub 2013 Feb 1.

PMID:
24429093
11.

The extent of emphysema in patients with COPD.

Shaker SB, Stavngaard T, Hestad M, Bach KS, Tonnesen P, Dirksen A.

Clin Respir J. 2009 Jan;3(1):15-21. doi: 10.1111/j.1752-699X.2008.00102.x.

PMID:
20298367
12.

Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team.

Vestbo J, Agusti A, Wouters EF, Bakke P, Calverley PM, Celli B, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, MacNee W, Miller B, Rennard SI, Silverman EK, Yates JC, Tal-Singer R; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints Study Investigators.

Am J Respir Crit Care Med. 2014 May 1;189(9):1022-30. doi: 10.1164/rccm.201311-2006PP.

PMID:
24552242
13.

Correlation between serum biomarkers and BODE index in patients with stable COPD.

Liu SF, Chin CH, Wang CC, Lin MC.

Respirology. 2009 Sep;14(7):999-1004. doi: 10.1111/j.1440-1843.2009.01608.x.

PMID:
19740260
14.

Diagnosis of chronic obstructive pulmonary disease in lung cancer screening Computed Tomography scans: independent contribution of emphysema, air trapping and bronchial wall thickening.

Mets OM, Schmidt M, Buckens CF, Gondrie MJ, Isgum I, Oudkerk M, Vliegenthart R, de Koning HJ, van der Aalst CM, Prokop M, Lammers JW, Zanen P, Mohamed Hoesein FA, Mali WP, van Ginneken B, van Rikxoort EM, de Jong PA.

Respir Res. 2013 May 27;14:59. doi: 10.1186/1465-9921-14-59.

15.

Greater whole-body myofibrillar protein breakdown in cachectic patients with chronic obstructive pulmonary disease.

Rutten EP, Franssen FM, Engelen MP, Wouters EF, Deutz NE, Schols AM.

Am J Clin Nutr. 2006 Apr;83(4):829-34.

16.

Serum cytokine profiling and enrichment analysis reveal the involvement of immunological and inflammatory pathways in stable patients with chronic obstructive pulmonary disease.

Bade G, Khan MA, Srivastava AK, Khare P, Solaiappan KK, Guleria R, Palaniyar N, Talwar A.

Int J Chron Obstruct Pulmon Dis. 2014 Aug 5;9:759-73. doi: 10.2147/COPD.S61347. eCollection 2014.

17.

Ventilation/perfusion SPECT in chronic obstructive pulmonary disease: an evaluation by reference to symptoms, spirometric lung function and emphysema, as assessed with HRCT.

Jögi J, Ekberg M, Jonson B, Bozovic G, Bajc M.

Eur J Nucl Med Mol Imaging. 2011 Jul;38(7):1344-52. doi: 10.1007/s00259-011-1757-5. Epub 2011 Mar 2.

PMID:
21365251
18.

Pilot analysis of the plasma metabolite profiles associated with emphysematous Chronic Obstructive Pulmonary Disease phenotype.

Paige M, Burdick MD, Kim S, Xu J, Lee JK, Shim YM.

Biochem Biophys Res Commun. 2011 Oct 7;413(4):588-93. doi: 10.1016/j.bbrc.2011.09.006. Epub 2011 Sep 8.

19.

Metabolic system alterations in pancreatic cancer patient serum: potential for early detection.

Ritchie SA, Akita H, Takemasa I, Eguchi H, Pastural E, Nagano H, Monden M, Doki Y, Mori M, Jin W, Sajobi TT, Jayasinghe D, Chitou B, Yamazaki Y, White T, Goodenowe DB.

BMC Cancer. 2013 Sep 12;13:416. doi: 10.1186/1471-2407-13-416.

20.

Exhaled nitric oxide measure using multiple flows in clinically relevant subgroups of COPD.

Bazeghi N, Gerds TA, Budtz-Jørgensen E, Hove J, Vestbo J.

Respir Med. 2011 Sep;105(9):1338-44. doi: 10.1016/j.rmed.2011.03.015. Epub 2011 May 6.

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