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1.

Role of PGC-1α signaling in skeletal muscle health and disease.

Kang C, Li Ji L.

Ann N Y Acad Sci. 2012 Oct;1271:110-7. doi: 10.1111/j.1749-6632.2012.06738.x. Review.

2.

PGC-1alpha-mediated adaptations in skeletal muscle.

Olesen J, Kiilerich K, Pilegaard H.

Pflugers Arch. 2010 Jun;460(1):153-62. doi: 10.1007/s00424-010-0834-0. Epub 2010 Apr 19. Review.

PMID:
20401754
3.

Exercise activation of muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling is redox sensitive.

Kang C, O'Moore KM, Dickman JR, Ji LL.

Free Radic Biol Med. 2009 Nov 15;47(10):1394-400. doi: 10.1016/j.freeradbiomed.2009.08.007. Epub 2009 Aug 14.

PMID:
19686839
4.

Exercise training attenuates aging-associated mitochondrial dysfunction in rat skeletal muscle: role of PGC-1α.

Kang C, Chung E, Diffee G, Ji LL.

Exp Gerontol. 2013 Nov;48(11):1343-50. doi: 10.1016/j.exger.2013.08.004. Epub 2013 Aug 30.

PMID:
23994518
5.

Deacetylation of PGC-1α by SIRT1: importance for skeletal muscle function and exercise-induced mitochondrial biogenesis.

Gurd BJ.

Appl Physiol Nutr Metab. 2011 Oct;36(5):589-97. doi: 10.1139/h11-070. Epub 2011 Sep 2. Review.

PMID:
21888529
6.

Decreased mRNA expression of PGC-1α and PGC-1α-regulated factors in the SOD1G93A ALS mouse model and in human sporadic ALS.

Thau N, Knippenberg S, Körner S, Rath KJ, Dengler R, Petri S.

J Neuropathol Exp Neurol. 2012 Dec;71(12):1064-74. doi: 10.1097/NEN.0b013e318275df4b.

PMID:
23147503
7.

PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells.

O'Hagan KA, Cocchiglia S, Zhdanov AV, Tambuwala MM, Cummins EP, Monfared M, Agbor TA, Garvey JF, Papkovsky DB, Taylor CT, Allan BB.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2188-93. doi: 10.1073/pnas.0808801106. Epub 2009 Jan 28. Erratum in: Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5449. Tambawala, Murtaza M [corrected to Tambuwala, Murtaza M].

9.

AMP-activated protein kinase is required for exercise-induced peroxisome proliferator-activated receptor co-activator 1 translocation to subsarcolemmal mitochondria in skeletal muscle.

Smith BK, Mukai K, Lally JS, Maher AC, Gurd BJ, Heigenhauser GJ, Spriet LL, Holloway GP.

J Physiol. 2013 Mar 15;591(Pt 6):1551-61. doi: 10.1113/jphysiol.2012.245944. Epub 2013 Jan 7.

10.

Striated muscle activator of Rho signalling (STARS) is a PGC-1α/oestrogen-related receptor-α target gene and is upregulated in human skeletal muscle after endurance exercise.

Wallace MA, Hock MB, Hazen BC, Kralli A, Snow RJ, Russell AP.

J Physiol. 2011 Apr 15;589(Pt 8):2027-39. doi: 10.1113/jphysiol.2011.205468. Epub 2011 Feb 21.

11.

PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle.

Norrbom J, Sundberg CJ, Ameln H, Kraus WE, Jansson E, Gustafsson T.

J Appl Physiol (1985). 2004 Jan;96(1):189-94. Epub 2003 Sep 12.

12.

Muscle immobilization and remobilization downregulates PGC-1α signaling and the mitochondrial biogenesis pathway.

Kang C, Ji LL.

J Appl Physiol (1985). 2013 Dec;115(11):1618-25. doi: 10.1152/japplphysiol.01354.2012. Epub 2013 Aug 22.

13.

Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle.

Egan B, Carson BP, Garcia-Roves PM, Chibalin AV, Sarsfield FM, Barron N, McCaffrey N, Moyna NM, Zierath JR, O'Gorman DJ.

J Physiol. 2010 May 15;588(Pt 10):1779-90. doi: 10.1113/jphysiol.2010.188011. Epub 2010 Mar 22.

14.

PPARgamma coactivator-1alpha expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations.

Irrcher I, Adhihetty PJ, Sheehan T, Joseph AM, Hood DA.

Am J Physiol Cell Physiol. 2003 Jun;284(6):C1669-77.

15.

Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.

Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C.

J Biol Chem. 2010 Oct 22;285(43):32793-800. doi: 10.1074/jbc.M110.145995. Epub 2010 Aug 17.

16.

Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle.

Gurd BJ, Yoshida Y, McFarlan JT, Holloway GP, Moyes CD, Heigenhauser GJ, Spriet L, Bonen A.

Am J Physiol Regul Integr Comp Physiol. 2011 Jul;301(1):R67-75. doi: 10.1152/ajpregu.00417.2010. Epub 2011 May 4.

17.

Acute endurance exercise increases the nuclear abundance of PGC-1alpha in trained human skeletal muscle.

Little JP, Safdar A, Cermak N, Tarnopolsky MA, Gibala MJ.

Am J Physiol Regul Integr Comp Physiol. 2010 Apr;298(4):R912-7. doi: 10.1152/ajpregu.00409.2009. Epub 2010 Jan 27.

19.

Cilostazol promotes mitochondrial biogenesis in human umbilical vein endothelial cells through activating the expression of PGC-1α.

Zuo L, Li Q, Sun B, Xu Z, Ge Z.

Biochem Biophys Res Commun. 2013 Mar 29;433(1):52-7. doi: 10.1016/j.bbrc.2013.02.068. Epub 2013 Feb 26.

PMID:
23485471
20.

Cold-induced PGC-1alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway.

Oliveira RL, Ueno M, de Souza CT, Pereira-da-Silva M, Gasparetti AL, Bezzera RM, Alberici LC, Vercesi AE, Saad MJ, Velloso LA.

Am J Physiol Endocrinol Metab. 2004 Oct;287(4):E686-95. Epub 2004 May 27.

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