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Items: 1 to 20 of 140

1.

ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

Alemu EA, Lamark T, Torgersen KM, Birgisdottir AB, Larsen KB, Jain A, Olsvik H, Øvervatn A, Kirkin V, Johansen T.

J Biol Chem. 2012 Nov 16;287(47):39275-90. doi: 10.1074/jbc.M112.378109. Epub 2012 Oct 5.

2.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

3.

Atg101, a novel mammalian autophagy protein interacting with Atg13.

Hosokawa N, Sasaki T, Iemura S, Natsume T, Hara T, Mizushima N.

Autophagy. 2009 Oct;5(7):973-9. Epub 2009 Oct 18.

PMID:
19597335
4.

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.

Popovic D, Akutsu M, Novak I, Harper JW, Behrends C, Dikic I.

Mol Cell Biol. 2012 May;32(9):1733-44. doi: 10.1128/MCB.06717-11. Epub 2012 Feb 21.

5.

The LIR motif - crucial for selective autophagy.

Birgisdottir ÅB, Lamark T, Johansen T.

J Cell Sci. 2013 Aug 1;126(Pt 15):3237-47. doi: 10.1242/jcs.126128. Review.

6.

Characterization of the interaction of GABARAPL-1 with the LIR motif of NBR1.

Rozenknop A, Rogov VV, Rogova NY, Löhr F, Güntert P, Dikic I, Dötsch V.

J Mol Biol. 2011 Jul 15;410(3):477-87. doi: 10.1016/j.jmb.2011.05.003. Epub 2011 May 18.

PMID:
21620860
7.

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.

Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH.

Mol Biol Cell. 2009 Apr;20(7):1992-2003. doi: 10.1091/mbc.E08-12-1249. Epub 2009 Feb 18.

8.

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

Mercer CA, Kaliappan A, Dennis PB.

Autophagy. 2009 Jul;5(5):649-62. Epub 2009 Jul 20.

PMID:
19287211
9.

TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death.

Seillier M, Peuget S, Gayet O, Gauthier C, N'Guessan P, Monte M, Carrier A, Iovanna JL, Dusetti NJ.

Cell Death Differ. 2012 Sep;19(9):1525-35. doi: 10.1038/cdd.2012.30. Epub 2012 Mar 16.

10.

FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy.

Olsvik HL, Lamark T, Takagi K, Larsen KB, Evjen G, Øvervatn A, Mizushima T, Johansen T.

J Biol Chem. 2015 Dec 4;290(49):29361-74. doi: 10.1074/jbc.M115.686915. Epub 2015 Oct 14.

PMID:
26468287
11.

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.

Chan EY, Longatti A, McKnight NC, Tooze SA.

Mol Cell Biol. 2009 Jan;29(1):157-71. doi: 10.1128/MCB.01082-08. Epub 2008 Oct 20.

12.

Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.

Alers S, Löffler AS, Paasch F, Dieterle AM, Keppeler H, Lauber K, Campbell DG, Fehrenbacher B, Schaller M, Wesselborg S, Stork B.

Autophagy. 2011 Dec;7(12):1423-33.

PMID:
22024743
13.

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.

Lystad AH, Ichimura Y, Takagi K, Yang Y, Pankiv S, Kanegae Y, Kageyama S, Suzuki M, Saito I, Mizushima T, Komatsu M, Simonsen A.

EMBO Rep. 2014 May;15(5):557-65. doi: 10.1002/embr.201338003. Epub 2014 Mar 25.

14.

iLIR: A web resource for prediction of Atg8-family interacting proteins.

Kalvari I, Tsompanis S, Mulakkal NC, Osgood R, Johansen T, Nezis IP, Promponas VJ.

Autophagy. 2014 May;10(5):913-25. doi: 10.4161/auto.28260. Epub 2014 Feb 26.

PMID:
24589857
15.

ATG13: just a companion, or an executor of the autophagic program?

Alers S, Wesselborg S, Stork B.

Autophagy. 2014 Jun;10(6):944-56. doi: 10.4161/auto.28987. Review. Erratum in: Autophagy. 2014 Aug;10(8):1481.

16.

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130.

Joachim J, Jefferies HB, Razi M, Frith D, Snijders AP, Chakravarty P, Judith D, Tooze SA.

Mol Cell. 2015 Dec 17;60(6):899-913. doi: 10.1016/j.molcel.2015.11.018.

17.

Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila.

Nagy P, Kárpáti M, Varga A, Pircs K, Venkei Z, Takáts S, Varga K, Erdi B, Hegedűs K, Juhász G.

Autophagy. 2014 Mar;10(3):453-67. doi: 10.4161/auto.27442. Epub 2014 Jan 6.

18.

Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.

Suzuki H, Tabata K, Morita E, Kawasaki M, Kato R, Dobson RC, Yoshimori T, Wakatsuki S.

Structure. 2014 Jan 7;22(1):47-58. doi: 10.1016/j.str.2013.09.023. Epub 2013 Nov 27.

19.

The LC3 interactome at a glance.

Wild P, McEwan DG, Dikic I.

J Cell Sci. 2014 Jan 1;127(Pt 1):3-9. doi: 10.1242/jcs.140426. Epub 2013 Dec 17. Review.

20.

Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17?

Hara T, Mizushima N.

Autophagy. 2009 Jan;5(1):85-7. Epub 2009 Jan 13.

PMID:
18981720
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