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Aging effects on DNA methylation modules in human brain and blood tissue.

Horvath S, Zhang Y, Langfelder P, Kahn RS, Boks MP, van Eijk K, van den Berg LH, Ophoff RA.

Genome Biol. 2012 Oct 3;13(10):R97. doi: 10.1186/gb-2012-13-10-r97.


Impacts of Chromatin States and Long-Range Genomic Segments on Aging and DNA Methylation.

Sun D, Yi SV.

PLoS One. 2015 Jun 19;10(6):e0128517. doi: 10.1371/journal.pone.0128517. eCollection 2015.


Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.

Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT.

PLoS Genet. 2009 Aug;5(8):e1000602. doi: 10.1371/journal.pgen.1000602. Epub 2009 Aug 14.


Acceleration of age-associated methylation patterns in HIV-1-infected adults.

Rickabaugh TM, Baxter RM, Sehl M, Sinsheimer JS, Hultin PM, Hultin LE, Quach A, Martínez-Maza O, Horvath S, Vilain E, Jamieson BD.

PLoS One. 2015 Mar 25;10(3):e0119201. doi: 10.1371/journal.pone.0119201. eCollection 2015.


Distinct DNA methylation changes highly correlated with chronological age in the human brain.

Hernandez DG, Nalls MA, Gibbs JR, Arepalli S, van der Brug M, Chong S, Moore M, Longo DL, Cookson MR, Traynor BJ, Singleton AB.

Hum Mol Genet. 2011 Mar 15;20(6):1164-72. doi: 10.1093/hmg/ddq561. Epub 2011 Jan 7.


Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites.

Florath I, Butterbach K, Müller H, Bewerunge-Hudler M, Brenner H.

Hum Mol Genet. 2014 Mar 1;23(5):1186-201. doi: 10.1093/hmg/ddt531. Epub 2013 Oct 26.


Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging.

Chu MW, Siegmund KD, Eckstam CL, Kim JY, Yang AS, Kanel GC, Tavaré S, Shibata D.

BMC Med Genet. 2007 Jul 31;8:50.


Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape.

Day K, Waite LL, Thalacker-Mercer A, West A, Bamman MM, Brooks JD, Myers RM, Absher D.

Genome Biol. 2013;14(9):R102.


A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects.

McClay JL, Aberg KA, Clark SL, Nerella S, Kumar G, Xie LY, Hudson AD, Harada A, Hultman CM, Magnusson PK, Sullivan PF, Van Den Oord EJ.

Hum Mol Genet. 2014 Mar 1;23(5):1175-85. doi: 10.1093/hmg/ddt511. Epub 2013 Oct 16.


DNA methylation signatures in development and aging of the human prefrontal cortex.

Numata S, Ye T, Hyde TM, Guitart-Navarro X, Tao R, Wininger M, Colantuoni C, Weinberger DR, Kleinman JE, Lipska BK.

Am J Hum Genet. 2012 Feb 10;90(2):260-72. doi: 10.1016/j.ajhg.2011.12.020. Epub 2012 Feb 2. Erratum in: Am J Hum Genet. 2012 Oct 5;91(4):765.


Characterization of age signatures of DNA methylation in normal and cancer tissues from multiple studies.

Kim J, Kim K, Kim H, Yoon G, Lee K.

BMC Genomics. 2014 Nov 19;15:997. doi: 10.1186/1471-2164-15-997.


Age-associated hyper-methylated regions in the human brain overlap with bivalent chromatin domains.

Watson CT, Disanto G, Sandve GK, Breden F, Giovannoni G, Ramagopalan SV.

PLoS One. 2012;7(9):e43840. doi: 10.1371/journal.pone.0043840. Epub 2012 Sep 24.


Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging.

Haberman RP, Quigley CK, Gallagher M.

Epigenetics. 2012 Sep;7(9):1008-19. Epub 2012 Aug 7.


Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation.

Johnson KC, Koestler DC, Cheng C, Christensen BC.

Epigenetics. 2014 Feb;9(2):268-75. doi: 10.4161/epi.27015. Epub 2013 Nov 6.


Fundamental diversity of human CpG islands at multiple biological levels.

Zeng J, Nagrajan HK, Yi SV.

Epigenetics. 2014 Apr;9(4):483-91. doi: 10.4161/epi.27654. Epub 2014 Jan 13.


Developing a DNA methylation assay for human age prediction in blood and bloodstain.

Huang Y, Yan J, Hou J, Fu X, Li L, Hou Y.

Forensic Sci Int Genet. 2015 Jul;17:129-36. doi: 10.1016/j.fsigen.2015.05.007. Epub 2015 May 8.


High preservation of CpG cytosine methylation patterns at imprinted gene loci in liver and brain of aged mice.

Gravina S, Dollé ME, Wang T, van Steeg H, Hasty P, Hoeijmakers J, Vijg J.

PLoS One. 2013 Sep 9;8(9):e73496. doi: 10.1371/journal.pone.0073496. eCollection 2013.


Methylomic trajectories across human fetal brain development.

Spiers H, Hannon E, Schalkwyk LC, Smith R, Wong CC, O'Donovan MC, Bray NJ, Mill J.

Genome Res. 2015 Mar;25(3):338-52. doi: 10.1101/gr.180273.114. Epub 2015 Feb 3.

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