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Results: 1 to 20 of 136

1.

Rescue the failed half-ZFN by a sensitive mammalian cell-based luciferase reporter system.

Zhang W, Guo Y, Zhang C, Ji H, Meng W, Wang D, Li X, Mao Q, Xia H.

PLoS One. 2012;7(9):e45169. doi: 10.1371/journal.pone.0045169. Epub 2012 Sep 18.

PMID:
23028823
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Establishment of a cell line carrying single copy of an exogenous mutant reporter gene for assaying the biological activity of ZFNs.

Zhang W, Zheng X, Wang Y, Mao Q, Xia H.

J Biotechnol. 2012 Dec 31;162(2-3):191-6. doi: 10.1016/j.jbiotec.2012.10.002. Epub 2012 Oct 17.

PMID:
23085434
[PubMed - indexed for MEDLINE]
3.

Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).

Foley JE, Yeh JR, Maeder ML, Reyon D, Sander JD, Peterson RT, Joung JK.

PLoS One. 2009;4(2):e4348. doi: 10.1371/journal.pone.0004348. Epub 2009 Feb 9.

PMID:
19198653
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Genome editing with CompoZr custom zinc finger nucleases (ZFNs).

Hansen K, Coussens MJ, Sago J, Subramanian S, Gjoka M, Briner D.

J Vis Exp. 2012 Jun 14;(64):e3304. doi: 10.3791/3304.

PMID:
22732945
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling.

Xiong K, Li S, Zhang H, Cui Y, Yu D, Li Y, Sun W, Fu Y, Teng Y, Liu Z, Zhou X, Xiao P, Li J, Liu H, Chen J.

Mol Biol Rep. 2013 Jul;40(7):4251-6. doi: 10.1007/s11033-013-2507-5. Epub 2013 May 5.

PMID:
23645027
[PubMed - indexed for MEDLINE]
6.

[The mechanism and application of zinc finger nucleases].

Zhong Q, Zhao SH.

Yi Chuan. 2011 Feb;33(2):123-30. Review. Chinese.

PMID:
21377968
[PubMed - indexed for MEDLINE]
7.

Simultaneous screening and validation of effective zinc finger nucleases in yeast.

Wang L, Lin J, Zhang T, Xu K, Ren C, Zhang Z.

PLoS One. 2013 May 31;8(5):e64687. doi: 10.1371/journal.pone.0064687. Print 2013.

PMID:
23741369
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly.

Kim HJ, Lee HJ, Kim H, Cho SW, Kim JS.

Genome Res. 2009 Jul;19(7):1279-88. doi: 10.1101/gr.089417.108. Epub 2009 May 21.

PMID:
19470664
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms.

Reyon D, Kirkpatrick JR, Sander JD, Zhang F, Voytas DF, Joung JK, Dobbs D, Coffman CR.

BMC Genomics. 2011 Jan 28;12:83. doi: 10.1186/1471-2164-12-83.

PMID:
21276248
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.

Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, Göbel C, Dassie JP, Pruett-Miller SM, Porteus MH, Sgroi DC, Iafrate AJ, Dobbs D, McCray PB Jr, Cathomen T, Voytas DF, Joung JK.

Mol Cell. 2008 Jul 25;31(2):294-301. doi: 10.1016/j.molcel.2008.06.016.

PMID:
18657511
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Versatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors.

Händel EM, Gellhaus K, Khan K, Bednarski C, Cornu TI, Müller-Lerch F, Kotin RM, Heilbronn R, Cathomen T.

Hum Gene Ther. 2012 Mar;23(3):321-9. doi: 10.1089/hum.2011.140. Epub 2011 Dec 14.

PMID:
21980922
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases.

Cornu TI, Thibodeau-Beganny S, Guhl E, Alwin S, Eichtinger M, Joung JK, Cathomen T.

Mol Ther. 2008 Feb;16(2):352-8. Epub 2007 Nov 20. Erratum in: Mol Ther. 2008 Nov;16(11):1898. Joung, J K [corrected to Joung, J Keith].

PMID:
18026168
[PubMed - indexed for MEDLINE]
13.

Adding fingers to an engineered zinc finger nuclease can reduce activity.

Shimizu Y, Şöllü C, Meckler JF, Adriaenssens A, Zykovich A, Cathomen T, Segal DJ.

Biochemistry. 2011 Jun 7;50(22):5033-41. doi: 10.1021/bi200393g. Epub 2011 May 11.

PMID:
21528840
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

In vitro assessment of zinc finger nuclease activity.

Cathomen T, Söllü C.

Methods Mol Biol. 2010;649:227-35. doi: 10.1007/978-1-60761-753-2_13.

PMID:
20680837
[PubMed - indexed for MEDLINE]
15.

Cell Biology Symposium: Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome.

Whyte JJ, Prather RS.

J Anim Sci. 2012 Apr;90(4):1111-7. doi: 10.2527/jas.2011-4546. Epub 2011 Oct 28. Review.

PMID:
22038991
[PubMed - indexed for MEDLINE]
Free Article
16.

Nontransgenic genome modification in plant cells.

Marton I, Zuker A, Shklarman E, Zeevi V, Tovkach A, Roffe S, Ovadis M, Tzfira T, Vainstein A.

Plant Physiol. 2010 Nov;154(3):1079-87. doi: 10.1104/pp.110.164806. Epub 2010 Sep 27.

PMID:
20876340
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes.

Kandavelou K, Chandrasegaran S.

Methods Mol Biol. 2009;544:617-36. doi: 10.1007/978-1-59745-483-4_40.

PMID:
19488728
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Validation and expression of zinc finger nucleases in plant cells.

Tovkach A, Zeevi V, Tzfira T.

Methods Mol Biol. 2010;649:315-36. doi: 10.1007/978-1-60761-753-2_20.

PMID:
20680844
[PubMed - indexed for MEDLINE]
19.

Potential application of FoldX force field based protein modeling in zinc finger nucleases design.

He Z, Mei G, Zhao C, Chen Y.

Sci China Life Sci. 2011 May;54(5):442-9. doi: 10.1007/s11427-011-4159-9. Epub 2011 Mar 31.

PMID:
21455692
[PubMed - indexed for MEDLINE]
20.

Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells.

Durai S, Mani M, Kandavelou K, Wu J, Porteus MH, Chandrasegaran S.

Nucleic Acids Res. 2005 Oct 26;33(18):5978-90. Print 2005. Review.

PMID:
16251401
[PubMed - indexed for MEDLINE]
Free PMC Article

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