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Results: 1 to 20 of 121

1.

The inhibition of autophagy sensitises colon cancer cells with wild-type p53 but not mutant p53 to topotecan treatment.

Li DD, Sun T, Wu XQ, Chen SP, Deng R, Jiang S, Feng GK, Pan JX, Zhang XS, Zeng YX, Zhu XF.

PLoS One. 2012;7(9):e45058. Epub 2012 Sep 14.

PMID:
23024792
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells.

Wu S, Wang X, Chen J, Chen Y.

Biochem Biophys Res Commun. 2013 May 17;434(4):898-903. doi: 10.1016/j.bbrc.2013.04.053. Epub 2013 Apr 23.

PMID:
23624503
[PubMed - indexed for MEDLINE]
3.

Impact of p53 knockout and topotecan treatment on gene expression profiles in human colon carcinoma cells: a pharmacogenomic study.

Daoud SS, Munson PJ, Reinhold W, Young L, Prabhu VV, Yu Q, LaRose J, Kohn KW, Weinstein JN, Pommier Y.

Cancer Res. 2003 Jun 1;63(11):2782-93.

PMID:
12782583
[PubMed - indexed for MEDLINE]
Free Article
4.

Topotecan-triggered degradation of topoisomerase I is p53-dependent and impacts cell survival.

Tomicic MT, Christmann M, Kaina B.

Cancer Res. 2005 Oct 1;65(19):8920-6.

PMID:
16204064
[PubMed - indexed for MEDLINE]
Free Article
5.

Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells.

Yang B, Eshleman JR, Berger NA, Markowitz SD.

Clin Cancer Res. 1996 Oct;2(10):1649-57.

PMID:
9816112
[PubMed - indexed for MEDLINE]
Free Article
6.

Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells.

Wang N, Pan W, Zhu M, Zhang M, Hao X, Liang G, Feng Y.

Br J Pharmacol. 2011 Sep;164(2b):731-42. doi: 10.1111/j.1476-5381.2011.01349.x.

PMID:
21418191
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53.

Russo D, Ottaggio L, Foggetti G, Masini M, Masiello P, Fronza G, Menichini P.

Biochim Biophys Acta. 2013 Aug;1833(8):1904-13. doi: 10.1016/j.bbamcr.2013.03.020. Epub 2013 Mar 29.

PMID:
23545415
[PubMed - indexed for MEDLINE]
8.

Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.

Nagalingam A, Arbiser JL, Bonner MY, Saxena NK, Sharma D.

Breast Cancer Res. 2012 Feb 21;14(1):R35.

PMID:
22353783
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.

Lee SO, Andey T, Jin UH, Kim K, Singh M, Safe S.

Oncogene. 2012 Jul 5;31(27):3265-76. doi: 10.1038/onc.2011.504. Epub 2011 Nov 14. Erratum in: Oncogene. 2012 Jul 5;31(27):3310. Sachdeva, M [corrected to Singh, M].

PMID:
22081070
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Regulation of p53 stability and function in HCT116 colon cancer cells.

Kaeser MD, Pebernard S, Iggo RD.

J Biol Chem. 2004 Feb 27;279(9):7598-605. Epub 2003 Dec 9.

PMID:
14665630
[PubMed - indexed for MEDLINE]
Free Article
11.

Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent.

Nguyen D, Zajac-Kaye M, Rubinstein L, Voeller D, Tomaszewski JE, Kummar S, Chen AP, Pommier Y, Doroshow JH, Yang SX.

Cell Cycle. 2011 Dec 1;10(23):4074-82. doi: 10.4161/cc.10.23.18170. Epub 2011 Dec 1.

PMID:
22101337
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis.

Fiorini C, Menegazzi M, Padroni C, Dando I, Dalla Pozza E, Gregorelli A, Costanzo C, Palmieri M, Donadelli M.

Apoptosis. 2013 Mar;18(3):337-46. doi: 10.1007/s10495-012-0790-6.

PMID:
23238993
[PubMed - indexed for MEDLINE]
13.

MyD88 in DNA repair and cancer cell resistance to genotoxic drugs.

Kfoury A, Le Corf K, El Sabeh R, Journeaux A, Badran B, Hussein N, Lebecque S, Manié S, Renno T, Coste I.

J Natl Cancer Inst. 2013 Jul 3;105(13):937-46. doi: 10.1093/jnci/djt120. Epub 2013 Jun 13.

PMID:
23766530
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy.

Selvakumaran M, Amaravadi RK, Vasilevskaya IA, O'Dwyer PJ.

Clin Cancer Res. 2013 Jun 1;19(11):2995-3007. doi: 10.1158/1078-0432.CCR-12-1542. Epub 2013 Mar 5.

PMID:
23461901
[PubMed - indexed for MEDLINE]
Free Article
15.

Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.

Wang W, Kim SH, El-Deiry WS.

Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11003-8. Epub 2006 Jul 11.

PMID:
16835297
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity.

Qi W, Weber CR, Wasland K, Savkovic SD.

BMC Cancer. 2011 Jun 3;11:219. doi: 10.1186/1471-2407-11-219.

PMID:
21639915
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Acriflavine enhances radiosensitivity of colon cancer cells through endoplasmic reticulum stress-mediated apoptosis.

Lim MJ, Ahn JY, Han Y, Yu CH, Kim MH, Lee SL, Lim DS, Song JY.

Int J Biochem Cell Biol. 2012 Aug;44(8):1214-22. doi: 10.1016/j.biocel.2012.04.022. Epub 2012 May 4.

PMID:
22564437
[PubMed - indexed for MEDLINE]
18.

Effects of ΔNp73β on cisplatin treatment in colon cancer cells.

Lööf J, Pfeifer D, Ding Z, Sun XF, Zhang H.

Mol Carcinog. 2012 Aug;51(8):628-35. doi: 10.1002/mc.20835. Epub 2011 Aug 11.

PMID:
21837762
[PubMed - indexed for MEDLINE]
19.

Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53.

Jing K, Song KS, Shin S, Kim N, Jeong S, Oh HR, Park JH, Seo KS, Heo JY, Han J, Park JI, Han C, Wu T, Kweon GR, Park SK, Yoon WH, Hwang BD, Lim K.

Autophagy. 2011 Nov;7(11):1348-58. doi: 10.4161/auto.7.11.16658. Epub 2011 Nov 1.

PMID:
21811093
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy.

Grassilli E, Narloch R, Federzoni E, Ianzano L, Pisano F, Giovannoni R, Romano G, Masiero L, Leone BE, Bonin S, Donada M, Stanta G, Helin K, Lavitrano M.

Clin Cancer Res. 2013 Jul 15;19(14):3820-31. doi: 10.1158/1078-0432.CCR-12-3289. Epub 2013 May 31.

PMID:
23729362
[PubMed - indexed for MEDLINE]
Free Article

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