Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 90

1.

Part II. Development of novel colchicine-derived immunosuppressants with improved pharmacokinetic properties.

Chang DJ, Lee S, Jang J, Kim SO, Kim WJ, Suh YG.

Bioorg Med Chem Lett. 2012 Nov 1;22(21):6750-5. doi: 10.1016/j.bmcl.2012.08.068. Epub 2012 Aug 25.

PMID:
23017885
[PubMed - indexed for MEDLINE]
2.

Design, synthesis and identification of novel colchicine-derived immunosuppressant.

Chang DJ, Yoon EY, Lee GB, Kim SO, Kim WJ, Kim YM, Jung JW, An H, Suh YG.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4416-20. doi: 10.1016/j.bmcl.2009.05.054. Epub 2009 May 18.

PMID:
19502058
[PubMed - indexed for MEDLINE]
3.

Discovery of structurally simplified analogs of colchicine as an immunosuppressant.

Chang DJ, Kim WJ.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3121-5. doi: 10.1016/j.bmcl.2014.05.007. Epub 2014 May 14.

PMID:
24881570
[PubMed - in process]
4.

Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity.

Jang MY, Lin Y, De Jonghe S, Gao LJ, Vanderhoydonck B, Froeyen M, Rozenski J, Herman J, Louat T, Van Belle K, Waer M, Herdewijn P.

J Med Chem. 2011 Jan 27;54(2):655-68. doi: 10.1021/jm101254z. Epub 2010 Dec 20.

PMID:
21171614
[PubMed - indexed for MEDLINE]
5.

The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy.

Mclay LM, Halley F, Souness JE, McKenna J, Benning V, Birrell M, Burton B, Belvisi M, Collis A, Constan A, Foster M, Hele D, Jayyosi Z, Kelley M, Maslen C, Miller G, Ouldelhkim MC, Page K, Phipps S, Pollock K, Porter B, Ratcliffe AJ, Redford EJ, Webber S, Slater B, Thybaud V, Wilsher N.

Bioorg Med Chem. 2001 Feb;9(2):537-54.

PMID:
11249145
[PubMed - indexed for MEDLINE]
6.

Synthesis, biological evaluation and molecular docking studies of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents.

Zhang ZM, Zhang XW, Zhao ZZ, Yan R, Xu R, Gong HB, Zhu HL.

Bioorg Med Chem. 2012 May 15;20(10):3359-67. doi: 10.1016/j.bmc.2012.03.064. Epub 2012 Apr 4.

PMID:
22520630
[PubMed - indexed for MEDLINE]
7.

Synthesis and evaluation of a novel series of quinoline derivatives with immunosuppressive activity.

Liu GB, Xu JL, He CC, Chen G, Xu Q, Xu HX, Li JX.

Bioorg Med Chem. 2009 Aug 1;17(15):5433-41. doi: 10.1016/j.bmc.2009.06.043. Epub 2009 Jun 26.

PMID:
19596582
[PubMed - indexed for MEDLINE]
8.

CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.

Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM.

Biochem Pharmacol. 2008 Jul 1;76(1):79-90. doi: 10.1016/j.bcp.2008.04.006. Epub 2008 Apr 18.

PMID:
18513703
[PubMed - indexed for MEDLINE]
9.

Discovery of novel 1,2,4-thiadiazole derivatives as potent, orally active agonists of sphingosine 1-phosphate receptor subtype 1 (S1P(1)).

Ren F, Deng G, Wang H, Luan L, Meng Q, Xu Q, Xu H, Xu X, Zhang H, Zhao B, Li C, Guo TB, Yang J, Zhang W, Zhao Y, Jia Q, Lu H, Xiang JN, Elliott JD, Lin X.

J Med Chem. 2012 May 10;55(9):4286-96. doi: 10.1021/jm2016107. Epub 2012 Apr 20.

PMID:
22500954
[PubMed - indexed for MEDLINE]
10.

Synthesis and antitumor activity of nitrogen-based thiocolchicine derivatives.

Wang B, Pan XD, Liu HY, Yang J, Lü ZY, Zhao JH.

Yao Xue Xue Bao. 2006 Nov;41(11):1057-63.

PMID:
17262947
[PubMed - indexed for MEDLINE]
11.

32-Ascomycinyloxyacetic acid derived immunosuppressants. Independence of immunophilin binding and immunosuppressive potency.

Wagner R, Rhoades TA, Or YS, Lane BC, Hsieh G, Mollison KW, Luly JR.

J Med Chem. 1998 May 21;41(11):1764-76.

PMID:
9599228
[PubMed - indexed for MEDLINE]
12.

Synthesis, biological evaluation of chrysin derivatives as potential immunosuppressive agents.

Lv PC, Cai TT, Qian Y, Sun J, Zhu HL.

Eur J Med Chem. 2011 Jan;46(1):393-8. doi: 10.1016/j.ejmech.2010.10.034. Epub 2010 Nov 10.

PMID:
21131104
[PubMed - indexed for MEDLINE]
13.

SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer.

Novotny-Diermayr V, Sangthongpitag K, Hu CY, Wu X, Sausgruber N, Yeo P, Greicius G, Pettersson S, Liang AL, Loh YK, Bonday Z, Goh KC, Hentze H, Hart S, Wang H, Ethirajulu K, Wood JM.

Mol Cancer Ther. 2010 Mar;9(3):642-52. doi: 10.1158/1535-7163.MCT-09-0689. Epub 2010 Mar 2.

PMID:
20197387
[PubMed - indexed for MEDLINE]
Free Article
14.

Synthesis and immunosuppressant activity of pyrazole carboxamides.

Wang AX, Xie Q, Lane B, Mollison KW, Hsieh GC, Marsh K, Sheets MP, Luly JR, Coghlan MJ.

Bioorg Med Chem Lett. 1998 Oct 6;8(19):2787-92.

PMID:
9873623
[PubMed - indexed for MEDLINE]
15.

Synthesis of novel cinnamanilides as potential immunosuppressive agents.

Shi L, Wang L, Wang Z, Zhu HL, Song Q.

Eur J Med Chem. 2012 Jan;47(1):585-93. doi: 10.1016/j.ejmech.2011.10.027. Epub 2011 Oct 20.

PMID:
22104970
[PubMed - indexed for MEDLINE]
16.

N-Alkylidenearylcarboxamides as new potent and selective CB(2) cannabinoid receptor agonists with good oral bioavailability.

Ohta H, Ishizaka T, Tatsuzuki M, Yoshinaga M, Iida I, Tomishima Y, Toda Y, Saito S.

Bioorg Med Chem Lett. 2007 Nov 15;17(22):6299-304. Epub 2007 Sep 7.

PMID:
17884496
[PubMed - indexed for MEDLINE]
17.

Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent.

Bantia S, Miller PJ, Parker CD, Ananth SL, Horn LL, Kilpatrick JM, Morris PE, Hutchison TL, Montgomery JA, Sandhu JS.

Int Immunopharmacol. 2001 Jun;1(6):1199-210.

PMID:
11407314
[PubMed - indexed for MEDLINE]
18.

A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis.

Sumariwalla PF, Gallily R, Tchilibon S, Fride E, Mechoulam R, Feldmann M.

Arthritis Rheum. 2004 Mar;50(3):985-98.

PMID:
15022343
[PubMed - indexed for MEDLINE]
Free Article
19.

Discovery of a novel orally active PDE-4 inhibitor effective in an ovalbumin-induced asthma murine model.

Kwak HJ, Nam JY, Song JS, No Z, Yang SD, Cheon HG.

Eur J Pharmacol. 2012 Jun 15;685(1-3):141-8. doi: 10.1016/j.ejphar.2012.04.016. Epub 2012 Apr 20.

PMID:
22554769
[PubMed - indexed for MEDLINE]
20.

Immunosuppressive effects of new cyclolanostane triterpene diglycosides from the aerial part of Cimicifuga foetida.

Pan RL, Chen DH, Si JY, Zhao XH, Li Z, Cao L.

Arch Pharm Res. 2009 Feb;32(2):185-90. doi: 10.1007/s12272-009-1133-1. Epub 2009 Mar 13.

PMID:
19280146
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk