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High hepatic SCD1 activity is associated with low liver fat content in healthy subjects under a lipogenic diet.

Silbernagel G, Kovarova M, Cegan A, Machann J, Schick F, Lehmann R, Häring HU, Stefan N, Schleicher E, Fritsche A, Peter A.

J Clin Endocrinol Metab. 2012 Dec;97(12):E2288-92. doi: 10.1210/jc.2012-2152. Epub 2012 Sep 26.


Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding.

Chong MF, Hodson L, Bickerton AS, Roberts R, Neville M, Karpe F, Frayn KN, Fielding BA.

Am J Clin Nutr. 2008 Apr;87(4):817-23.


Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis.

Lee JJ, Lambert JE, Hovhannisyan Y, Ramos-Roman MA, Trombold JR, Wagner DA, Parks EJ.

Am J Clin Nutr. 2015 Jan;101(1):34-43. doi: 10.3945/ajcn.114.092262. Epub 2014 Nov 19.


Hepatic lipid composition and stearoyl-coenzyme A desaturase 1 mRNA expression can be estimated from plasma VLDL fatty acid ratios.

Peter A, Cegan A, Wagner S, Lehmann R, Stefan N, Königsrainer A, Königsrainer I, Häring HU, Schleicher E.

Clin Chem. 2009 Dec;55(12):2113-20. doi: 10.1373/clinchem.2009.127274. Epub 2009 Oct 22.


A dual sugar challenge test for lipogenic sensitivity to dietary fructose.

Hudgins LC, Parker TS, Levine DM, Hellerstein MK.

J Clin Endocrinol Metab. 2011 Mar;96(3):861-8. doi: 10.1210/jc.2010-2007. Epub 2011 Jan 20.


Relationships between hepatic stearoyl-CoA desaturase-1 activity and mRNA expression with liver fat content in humans.

Peter A, Cegan A, Wagner S, Elcnerova M, Königsrainer A, Königsrainer I, Häring HU, Schleicher ED, Stefan N.

Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E321-6. doi: 10.1152/ajpendo.00306.2010. Epub 2010 Nov 2.


Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans.

Stefan N, Peter A, Cegan A, Staiger H, Machann J, Schick F, Claussen CD, Fritsche A, Häring HU, Schleicher E.

Diabetologia. 2008 Apr;51(4):648-56. doi: 10.1007/s00125-008-0938-7. Epub 2008 Feb 20.


Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans.

Sevastianova K, Santos A, Kotronen A, Hakkarainen A, Makkonen J, Silander K, Peltonen M, Romeo S, Lundbom J, Lundbom N, Olkkonen VM, Gylling H, Fielding BA, Rissanen A, Yki-Järvinen H.

Am J Clin Nutr. 2012 Oct;96(4):727-34. Epub 2012 Sep 5.


Sources of hepatic triglyceride accumulation during high-fat feeding in the healthy rat.

Delgado TC, Pinheiro D, Caldeira M, Castro MM, Geraldes CF, López-Larrubia P, Cerdán S, Jones JG.

NMR Biomed. 2009 Apr;22(3):310-7. doi: 10.1002/nbm.1327.


Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis.

Harmancey R, Wilson CR, Wright NR, Taegtmeyer H.

J Lipid Res. 2010 Jun;51(6):1380-93. doi: 10.1194/jlr.M001230. Epub 2010 Jan 21.


Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis.

Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X, Ntambi JM.

Cell Metab. 2007 Dec;6(6):484-96.


Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat.

Sampath H, Miyazaki M, Dobrzyn A, Ntambi JM.

J Biol Chem. 2007 Jan 26;282(4):2483-93. Epub 2006 Nov 23.


Sterculic oil, a natural inhibitor of SCD1, improves the metabolic state of obese OLETF rats.

Ortinau LC, Nickelson KJ, Stromsdorfer KL, Naik CY, Pickering RT, Haynes RA, Fritsche KL, Perfield JW 2nd.

Obesity (Silver Spring). 2013 Feb;21(2):344-52. doi: 10.1002/oby.20040.


Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet.

Flowers MT, Groen AK, Oler AT, Keller MP, Choi Y, Schueler KL, Richards OC, Lan H, Miyazaki M, Kuipers F, Kendziorski CM, Ntambi JM, Attie AD.

J Lipid Res. 2006 Dec;47(12):2668-80. Epub 2006 Sep 27.


Prominent role of liver in elevated plasma palmitoleate levels in response to rosiglitazone in mice fed high-fat diet.

Kuda O, Stankova B, Tvrzicka E, Hensler M, Jelenik T, Rossmeisl M, Flachs P, Kopecky J.

J Physiol Pharmacol. 2009 Dec;60(4):135-40.


Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet.

Cedernaes J, Alsiö J, Västermark A, Risérus U, Schiöth HB.

Lipids Health Dis. 2013 Jan 8;12:2. doi: 10.1186/1476-511X-12-2.


Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.

Ren LP, Chan SM, Zeng XY, Laybutt DR, Iseli TJ, Sun RQ, Kraegen EW, Cooney GJ, Turner N, Ye JM.

PLoS One. 2012;7(2):e30816. doi: 10.1371/journal.pone.0030816. Epub 2012 Feb 15.


Preventative effects of Platycodon grandiflorum treatment on hepatic steatosis in high fat diet-fed C57BL/6 mice.

Noh JR, Kim YH, Gang GT, Yang KJ, Kim SK, Ryu SY, Kim YS, Lee CH, Lee HS.

Biol Pharm Bull. 2010;33(3):450-4.

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