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Results: 1 to 20 of 231

1.

Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.

Tian J, Lee SO, Liang L, Luo J, Huang CK, Li L, Niu Y, Chang C.

J Biol Chem. 2012 Nov 16;287(47):39954-66. doi: 10.1074/jbc.M112.395574. Epub 2012 Sep 25.

PMID:
23012352
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Androgen receptor is negatively correlated with the methylation-mediated transcriptional repression of miR-375 in human prostate cancer cells.

Chu M, Chang Y, Li P, Guo Y, Zhang K, Gao W.

Oncol Rep. 2014 Jan;31(1):34-40. doi: 10.3892/or.2013.2810. Epub 2013 Oct 24.

PMID:
24173286
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells.

Lee SO, Ma Z, Yeh CR, Luo J, Lin TH, Lai KP, Yamashita S, Liang L, Tian J, Li L, Jiang Q, Huang CK, Niu Y, Yeh S, Chang C.

J Mol Cell Biol. 2013 Feb;5(1):14-26. doi: 10.1093/jmcb/mjs042. Epub 2012 Jul 24.

PMID:
22831834
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Epigenetic regulation of androgen receptor gene expression in human prostate cancers.

Nakayama T, Watanabe M, Suzuki H, Toyota M, Sekita N, Hirokawa Y, Mizokami A, Ito H, Yatani R, Shiraishi T.

Lab Invest. 2000 Dec;80(12):1789-96.

PMID:
11140692
[PubMed - indexed for MEDLINE]
5.

Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth.

Wolff DW, Xie Y, Deng C, Gatalica Z, Yang M, Wang B, Wang J, Lin MF, Abel PW, Tu Y.

Int J Cancer. 2012 Apr 1;130(7):1521-31. doi: 10.1002/ijc.26138. Epub 2011 Jun 9.

PMID:
21500190
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis.

Wang Z, Wang Z, Guo J, Li Y, Bavarva JH, Qian C, Brahimi-Horn MC, Tan D, Liu W.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3053-8. doi: 10.1073/pnas.1113356109. Epub 2012 Feb 6.

PMID:
22315407
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene.

Schayek H, Bentov I, Sun S, Plymate SR, Werner H.

Exp Cell Res. 2010 May 15;316(9):1479-88. doi: 10.1016/j.yexcr.2010.03.007. Epub 2010 Mar 23.

PMID:
20338164
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Human α(2)β(1)(HI) CD133(+VE) epithelial prostate stem cells express low levels of active androgen receptor.

Williamson SC, Hepburn AC, Wilson L, Coffey K, Ryan-Munden CA, Pal D, Leung HY, Robson CN, Heer R.

PLoS One. 2012;7(11):e48944. doi: 10.1371/journal.pone.0048944. Epub 2012 Nov 7.

PMID:
23145034
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.

Chiam K, Centenera MM, Butler LM, Tilley WD, Bianco-Miotto T.

PLoS One. 2011;6(9):e25634. doi: 10.1371/journal.pone.0025634. Epub 2011 Sep 28.

PMID:
21980513
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells.

Mishra DK, Chen Z, Wu Y, Sarkissyan M, Koeffler HP, Vadgama JV.

Mol Cancer Ther. 2010 Jan;9(1):33-45. doi: 10.1158/1535-7163.MCT-09-0486. Epub 2010 Jan 6.

PMID:
20053773
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Increased chemosensitivity via targeting testicular nuclear receptor 4 (TR4)-Oct4-interleukin 1 receptor antagonist (IL1Ra) axis in prostate cancer CD133+ stem/progenitor cells to battle prostate cancer.

Yang DR, Ding XF, Luo J, Shan YX, Wang R, Lin SJ, Li G, Huang CK, Zhu J, Chen Y, Lee SO, Chang C.

J Biol Chem. 2013 Jun 7;288(23):16476-83. doi: 10.1074/jbc.M112.448142. Epub 2013 Apr 22.

PMID:
23609451
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Methylation of the neutral endopeptidase gene promoter in human prostate cancers.

Usmani BA, Shen R, Janeczko M, Papandreou CN, Lee WH, Nelson WG, Nelson JB, Nanus DM.

Clin Cancer Res. 2000 May;6(5):1664-70.

PMID:
10815884
[PubMed - indexed for MEDLINE]
Free Article
13.

Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells.

Huss WJ, Gray DR, Greenberg NM, Mohler JL, Smith GJ.

Cancer Res. 2005 Aug 1;65(15):6640-50.

PMID:
16061644
[PubMed - indexed for MEDLINE]
Free Article
14.

Prostate cancer stem cells: do they have a basal or luminal phenotype?

Maitland NJ, Frame FM, Polson ES, Lewis JL, Collins AT.

Horm Cancer. 2011 Feb;2(1):47-61. doi: 10.1007/s12672-010-0058-y.

PMID:
21761340
[PubMed - indexed for MEDLINE]
15.

Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells.

Jarrard DF, Kinoshita H, Shi Y, Sandefur C, Hoff D, Meisner LF, Chang C, Herman JG, Isaacs WB, Nassif N.

Cancer Res. 1998 Dec 1;58(23):5310-4.

PMID:
9850055
[PubMed - indexed for MEDLINE]
Free Article
16.

Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis.

Guenin S, Mouallif M, Deplus R, Lampe X, Krusy N, Calonne E, Delbecque K, Kridelka F, Fuks F, Ennaji MM, Delvenne P.

PLoS One. 2012;7(8):e42704. doi: 10.1371/journal.pone.0042704. Epub 2012 Aug 3.

PMID:
22880087
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase.

Asim M, Hafeez BB, Siddiqui IA, Gerlach C, Patz M, Mukhtar H, Baniahmad A.

J Biol Chem. 2011 Oct 28;286(43):37108-17. doi: 10.1074/jbc.M111.292771. Epub 2011 Aug 19.

PMID:
21856747
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.

Henrique R, Costa VL, Cerveira N, Carvalho AL, Hoque MO, Ribeiro FR, Oliveira J, Teixeira MR, Sidransky D, Jerónimo C.

J Mol Med (Berl). 2006 Nov;84(11):911-8. Epub 2006 Sep 22.

PMID:
17016690
[PubMed - indexed for MEDLINE]
19.

Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model.

Chang HH, Chen BY, Wu CY, Tsao ZJ, Chen YY, Chang CP, Yang CR, Lin DP.

J Biomed Sci. 2011 Jan 18;18:6. doi: 10.1186/1423-0127-18-6.

PMID:
21241512
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

DNA methylation in the androgen receptor gene promoter region in rat prostate cancers.

Takahashi S, Inaguma S, Sakakibara M, Cho YM, Suzuki S, Ikeda Y, Cui L, Shirai T.

Prostate. 2002 Jun 1;52(1):82-8.

PMID:
11992622
[PubMed - indexed for MEDLINE]
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