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Results: 1 to 20 of 355

1.

TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation.

Nayar R, Enos M, Prince A, Shin H, Hemmers S, Jiang JK, Klein U, Thomas CJ, Berg LJ.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2794-802. doi: 10.1073/pnas.1205742109. Epub 2012 Sep 24.

PMID:
23011795
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.

Atherly LO, Lucas JA, Felices M, Yin CC, Reiner SL, Berg LJ.

Immunity. 2006 Jul;25(1):79-91.

PMID:
16860759
[PubMed - indexed for MEDLINE]
Free Article
3.

Histone acetyltransferase CBP is vital to demarcate conventional and innate CD8+ T-cell development.

Fukuyama T, Kasper LH, Boussouar F, Jeevan T, van Deursen J, Brindle PK.

Mol Cell Biol. 2009 Jul;29(14):3894-904. doi: 10.1128/MCB.01598-08. Epub 2009 May 11.

PMID:
19433445
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development.

Hu J, August A.

J Immunol. 2008 May 15;180(10):6544-52.

PMID:
18453573
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The absence of Itk inhibits positive selection without changing lineage commitment.

Lucas JA, Atherly LO, Berg LJ.

J Immunol. 2002 Jun 15;168(12):6142-51.

PMID:
12055226
[PubMed - indexed for MEDLINE]
Free Article
6.

Impaired thymic selection and abnormal antigen-specific T cell responses in Foxn1(Δ/Δ) mutant mice.

Xiao S, Manley NR.

PLoS One. 2010 Nov 4;5(11):e15396. doi: 10.1371/journal.pone.0015396.

PMID:
21079757
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Interferon regulatory factor 4 regulates thymocyte differentiation by repressing Runx3 expression.

Cao Y, Li H, Sun Y, Chen X, Liu H, Gao X, Liu X.

Eur J Immunol. 2010 Nov;40(11):3198-209. doi: 10.1002/eji.201040570. Epub 2010 Oct 27.

PMID:
21061442
[PubMed - indexed for MEDLINE]
8.
9.

Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk.

Hu J, Sahu N, Walsh E, August A.

Eur J Immunol. 2007 Oct;37(10):2892-9.

PMID:
17724684
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes.

Penninger JM, Sirard C, Mittrücker HW, Chidgey A, Kozieradzki I, Nghiem M, Hakem A, Kimura T, Timms E, Boyd R, Taniguchi T, Matsuyama T, Mak TW.

Immunity. 1997 Aug;7(2):243-54.

PMID:
9285409
[PubMed - indexed for MEDLINE]
Free Article
11.

Entry of CD4-CD8- immature thymocytes into the CD4/CD8 developmental pathway is controlled by tyrosine kinase signals that can be provided through TCR components.

Takahama Y, Hasegawa T, Itohara S, Ball EL, Sheard MA, Hashimoto Y.

Int Immunol. 1994 Oct;6(10):1505-14.

PMID:
7826942
[PubMed - indexed for MEDLINE]
12.

Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells.

Gomez-Rodriguez J, Wohlfert EA, Handon R, Meylan F, Wu JZ, Anderson SM, Kirby MR, Belkaid Y, Schwartzberg PL.

J Exp Med. 2014 Mar 10;211(3):529-43. doi: 10.1084/jem.20131459. Epub 2014 Feb 17.

PMID:
24534190
[PubMed - indexed for MEDLINE]
13.

Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells.

Gordon SM, Carty SA, Kim JS, Zou T, Smith-Garvin J, Alonzo ES, Haimm E, Sant'Angelo DB, Koretzky GA, Reiner SL, Jordan MS.

J Immunol. 2011 Apr 15;186(8):4573-8. doi: 10.4049/jimmunol.1100037. Epub 2011 Mar 7.

PMID:
21383242
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The quantity of TCR signal determines positive selection and lineage commitment of T cells.

Watanabe N, Arase H, Onodera M, Ohashi PS, Saito T.

J Immunol. 2000 Dec 1;165(11):6252-61.

PMID:
11086060
[PubMed - indexed for MEDLINE]
Free Article
15.

Preferential development of CD4 and CD8 T regulatory cells in RasGRP1-deficient mice.

Chen X, Priatel JJ, Chow MT, Teh HS.

J Immunol. 2008 May 1;180(9):5973-82.

PMID:
18424717
[PubMed - indexed for MEDLINE]
Free Article
16.

IL-2-inducible T-cell kinase modulates TH2-mediated allergic airway inflammation by suppressing IFN-γ in naive CD4+ T cells.

Kannan AK, Sahu N, Mohanan S, Mohinta S, August A.

J Allergy Clin Immunol. 2013 Oct;132(4):811-20.e1-5. doi: 10.1016/j.jaci.2013.04.033. Epub 2013 Jun 12.

PMID:
23768572
[PubMed - indexed for MEDLINE]
17.

Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.

Broussard C, Fleischacker C, Horai R, Chetana M, Venegas AM, Sharp LL, Hedrick SM, Fowlkes BJ, Schwartzberg PL.

Immunity. 2006 Jul;25(1):93-104. Erratum in: Immunity. 2006 Nov;25(5):849. Fleischecker, Christine [corrected to Fleischacker, Christine].

PMID:
16860760
[PubMed - indexed for MEDLINE]
Free Article
18.

T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex.

Yamashita M, Katsumata M, Iwashima M, Kimura M, Shimizu C, Kamata T, Shin T, Seki N, Suzuki S, Taniguchi M, Nakayama T.

J Exp Med. 2000 Jun 5;191(11):1869-79.

PMID:
10839803
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.

Barndt R, Dai MF, Zhuang Y.

J Immunol. 1999 Sep 15;163(6):3331-43.

PMID:
10477603
[PubMed - indexed for MEDLINE]
Free Article
20.

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