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Items: 1 to 20 of 121

1.

μ-Opioid receptor desensitization: homologous or heterologous?

Llorente J, Lowe JD, Sanderson HS, Tsisanova E, Kelly E, Henderson G, Bailey CP.

Eur J Neurosci. 2012 Dec;36(12):3636-42. doi: 10.1111/ejn.12003. Epub 2012 Sep 24.

2.

Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization.

Lowe JD, Sanderson HS, Cooke AE, Ostovar M, Tsisanova E, Withey SL, Chavkin C, Husbands SM, Kelly E, Henderson G, Bailey CP.

Mol Pharmacol. 2015 Aug;88(2):347-56. doi: 10.1124/mol.115.098293. Epub 2015 May 26.

PMID:
26013542
3.

Prolonged stimulation of μ-opioid receptors produces β-arrestin-2-mediated heterologous desensitization of α(2)-adrenoceptor function in locus ceruleus neurons.

Dang VC, Chieng BC, Christie MJ.

Mol Pharmacol. 2012 Sep;82(3):473-80. doi: 10.1124/mol.112.079350. Epub 2012 Jun 11.

5.

Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.

Bailey CP, Oldfield S, Llorente J, Caunt CJ, Teschemacher AG, Roberts L, McArdle CA, Smith FL, Dewey WL, Kelly E, Henderson G.

Br J Pharmacol. 2009 Sep;158(1):157-64. doi: 10.1111/j.1476-5381.2009.00140.x. Epub 2009 Mar 20.

7.

Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.

Bailey CP, Llorente J, Gabra BH, Smith FL, Dewey WL, Kelly E, Henderson G.

Eur J Neurosci. 2009 Jan;29(2):307-18. doi: 10.1111/j.1460-9568.2008.06573.x.

8.
9.

The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacy.

Hull LC, Llorente J, Gabra BH, Smith FL, Kelly E, Bailey C, Henderson G, Dewey WL.

J Pharmacol Exp Ther. 2010 Mar;332(3):1127-35. doi: 10.1124/jpet.109.161455. Epub 2009 Dec 14.

10.

Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells.

Johnson EA, Oldfield S, Braksator E, Gonzalez-Cuello A, Couch D, Hall KJ, Mundell SJ, Bailey CP, Kelly E, Henderson G.

Mol Pharmacol. 2006 Aug;70(2):676-85. Epub 2006 May 8.

11.

Effects of orexin (hypocretin) on GIRK channels.

Hoang QV, Bajic D, Yanagisawa M, Nakajima S, Nakajima Y.

J Neurophysiol. 2003 Aug;90(2):693-702. Epub 2003 Apr 17.

12.

Desensitization of mu-opioid receptor-evoked potassium currents: initiation at the receptor, expression at the effector.

Blanchet C, Lüscher C.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4674-9. Epub 2002 Mar 26.

13.

Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes.

Celver JP, Lowe J, Kovoor A, Gurevich VV, Chavkin C.

J Biol Chem. 2001 Feb 16;276(7):4894-900. Epub 2000 Nov 1.

15.

Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons.

Llorente J, Withey S, Rivero G, Cunningham M, Cooke A, Saxena K, McPherson J, Oldfield S, Dewey WL, Bailey CP, Kelly E, Henderson G.

Mol Pharmacol. 2013 Aug;84(2):252-60. doi: 10.1124/mol.113.085936. Epub 2013 May 28.

16.

Endomorphin-2: a biased agonist at the μ-opioid receptor.

Rivero G, Llorente J, McPherson J, Cooke A, Mundell SJ, McArdle CA, Rosethorne EM, Charlton SJ, Krasel C, Bailey CP, Henderson G, Kelly E.

Mol Pharmacol. 2012 Aug;82(2):178-88. doi: 10.1124/mol.112.078659. Epub 2012 May 2.

17.

GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.

Moulédous L, Froment C, Dauvillier S, Burlet-Schiltz O, Zajac JM, Mollereau C.

J Biol Chem. 2012 Apr 13;287(16):12736-49. doi: 10.1074/jbc.M111.314617. Epub 2012 Feb 28.

19.

p38 MAPK and beta-arrestin 2 mediate functional interactions between endogenous micro-opioid and alpha2A-adrenergic receptors in neurons.

Tan M, Walwyn WM, Evans CJ, Xie CW.

J Biol Chem. 2009 Mar 6;284(10):6270-81. doi: 10.1074/jbc.M806742200. Epub 2009 Jan 6.

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