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Results: 1 to 20 of 82

1.

Asleep at the switch: MEK kinases control transit to gliogenesis in developing cortex.

Zhou J, Stiles CD.

Neuron. 2012 Sep 20;75(6):940-2. doi: 10.1016/j.neuron.2012.09.003.

PMID:
22998861
[PubMed - indexed for MEDLINE]
Free Article
2.

MEK Is a Key Regulator of Gliogenesis in the Developing Brain.

Li X, Newbern JM, Wu Y, Morgan-Smith M, Zhong J, Charron J, Snider WD.

Neuron. 2012 Sep 20;75(6):1035-50. doi: 10.1016/j.neuron.2012.08.031.

PMID:
22998872
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Differential expression of MEK1 and MEK2 during mouse development.

Alessandrini A, Brott BK, Erikson RL.

Cell Growth Differ. 1997 May;8(5):505-11.

PMID:
9149902
[PubMed - indexed for MEDLINE]
Free Article
4.

MEK ablation in MCF-7 cells blocks DNA synthesis induced by serum, but not by estradiol or growth factors.

Estes NR 2nd, Thottassery JV, Westbrook L, Kern FG.

Int J Oncol. 2006 Dec;29(6):1573-80.

PMID:
17088999
[PubMed - indexed for MEDLINE]
5.

An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis.

Ménard C, Hein P, Paquin A, Savelson A, Yang XM, Lederfein D, Barnabé-Heider F, Mir AA, Sterneck E, Peterson AC, Johnson PF, Vinson C, Miller FD.

Neuron. 2002 Nov 14;36(4):597-610.

PMID:
12441050
[PubMed - indexed for MEDLINE]
Free Article
6.

Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1).

Dwivedi Y, Rizavi HS, Zhang H, Roberts RC, Conley RR, Pandey GN.

Int J Neuropsychopharmacol. 2009 Nov;12(10):1337-54. doi: 10.1017/S1461145709990575.

PMID:
19835659
[PubMed - indexed for MEDLINE]
7.

MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.

Brott BK, Alessandrini A, Largaespada DA, Copeland NG, Jenkins NA, Crews CM, Erikson RL.

Cell Growth Differ. 1993 Nov;4(11):921-9.

PMID:
8297798
[PubMed - indexed for MEDLINE]
Free Article
8.

Mek2 is dispensable for mouse growth and development.

Bélanger LF, Roy S, Tremblay M, Brott B, Steff AM, Mourad W, Hugo P, Erikson R, Charron J.

Mol Cell Biol. 2003 Jul;23(14):4778-87.

PMID:
12832465
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.

Catalanotti F, Reyes G, Jesenberger V, Galabova-Kovacs G, de Matos Simoes R, Carugo O, Baccarini M.

Nat Struct Mol Biol. 2009 Mar;16(3):294-303. doi: 10.1038/nsmb.1564. Epub 2009 Feb 15.

PMID:
19219045
[PubMed - indexed for MEDLINE]
10.

Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.

Zheng CF, Guan KL.

J Biol Chem. 1993 May 25;268(15):11435-9.

PMID:
8388392
[PubMed - indexed for MEDLINE]
Free Article
11.

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta.

Giroux S, Tremblay M, Bernard D, Cardin-Girard JF, Aubry S, Larouche L, Rousseau S, Huot J, Landry J, Jeannotte L, Charron J.

Curr Biol. 1999 Apr 8;9(7):369-72.

PMID:
10209122
[PubMed - indexed for MEDLINE]
Free Article
12.

MEK1 and MEK2, different regulators of the G1/S transition.

Ussar S, Voss T.

J Biol Chem. 2004 Oct 15;279(42):43861-9. Epub 2004 Jul 28.

PMID:
15284233
[PubMed - indexed for MEDLINE]
Free Article
13.

CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo.

Paquin A, Barnabé-Heider F, Kageyama R, Miller FD.

J Neurosci. 2005 Nov 16;25(46):10747-58.

PMID:
16291948
[PubMed - indexed for MEDLINE]
Free Article
14.

Truncated tyrosine kinase B brain-derived neurotrophic factor receptor directs cortical neural stem cells to a glial cell fate by a novel signaling mechanism.

Cheng A, Coksaygan T, Tang H, Khatri R, Balice-Gordon RJ, Rao MS, Mattson MP.

J Neurochem. 2007 Mar;100(6):1515-30. Epub 2006 Dec 22.

PMID:
17286628
[PubMed - indexed for MEDLINE]
15.

BDNF/MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration.

Ortega JA, Alcántara S.

Cereb Cortex. 2010 Sep;20(9):2132-44. doi: 10.1093/cercor/bhp275. Epub 2009 Dec 27.

PMID:
20038543
[PubMed - indexed for MEDLINE]
Free Article
16.

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.

Xu S, Robbins D, Frost J, Dang A, Lange-Carter C, Cobb MH.

Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6808-12.

PMID:
7624324
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Stimulation of mitogen-activated protein kinase kinases (MEK1/2) by mu-, delta- and kappa-opioid receptor agonists in the rat brain: regulation by chronic morphine and opioid withdrawal.

Asensio VJ, Miralles A, García-Sevilla JA.

Eur J Pharmacol. 2006 Jun 6;539(1-2):49-56. Epub 2006 Apr 6.

PMID:
16678156
[PubMed - indexed for MEDLINE]
18.

Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2.

Zhang H, Feng H, Luo L, Zhou Q, Luo Z, Peng Y.

Virus Res. 2010 Jun;150(1-2):22-7. doi: 10.1016/j.virusres.2010.02.007. Epub 2010 Feb 19.

PMID:
20172001
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors.

Geest CR, Buitenhuis M, Groot Koerkamp MJ, Holstege FC, Vellenga E, Coffer PJ.

Blood. 2009 Oct 15;114(16):3402-12. doi: 10.1182/blood-2008-08-175141. Epub 2009 Aug 10.

PMID:
19667405
[PubMed - indexed for MEDLINE]
Free Article
20.

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.

Ohren JF, Chen H, Pavlovsky A, Whitehead C, Zhang E, Kuffa P, Yan C, McConnell P, Spessard C, Banotai C, Mueller WT, Delaney A, Omer C, Sebolt-Leopold J, Dudley DT, Leung IK, Flamme C, Warmus J, Kaufman M, Barrett S, Tecle H, Hasemann CA.

Nat Struct Mol Biol. 2004 Dec;11(12):1192-7. Epub 2004 Nov 14. Erratum in: Nat Struct Mol Biol. 2005 Mar;12(3):278.

PMID:
15543157
[PubMed - indexed for MEDLINE]

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