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Items: 1 to 20 of 130

1.

Localization of cholesterol, amyloid and glia in Alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging.

Solé-Domènech S, Sjövall P, Vukojević V, Fernando R, Codita A, Salve S, Bogdanović N, Mohammed AH, Hammarström P, Nilsson KP, LaFerla FM, Jacob S, Berggren PO, Giménez-Llort L, Schalling M, Terenius L, Johansson B.

Acta Neuropathol. 2013 Jan;125(1):145-57. doi: 10.1007/s00401-012-1046-9. Epub 2012 Sep 21.

PMID:
22996963
2.

Simultaneous imaging of amyloid-β and lipids in brain tissue using antibody-coupled liposomes and time-of-flight secondary ion mass spectrometry.

Carlred L, Gunnarsson A, Solé-Domènech S, Johansson B, Vukojević V, Terenius L, Codita A, Winblad B, Schalling M, Höök F, Sjövall P.

J Am Chem Soc. 2014 Jul 16;136(28):9973-81. doi: 10.1021/ja5019145. Epub 2014 Jun 30.

PMID:
24941267
3.

Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.

Cras P, Kawai M, Siedlak S, Mulvihill P, Gambetti P, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G.

Am J Pathol. 1990 Aug;137(2):241-6.

4.

PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures.

Brendza RP, O'Brien C, Simmons K, McKeel DW, Bales KR, Paul SM, Olney JW, Sanes JR, Holtzman DM.

J Comp Neurol. 2003 Feb 17;456(4):375-83.

PMID:
12532409
5.

Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain.

Wengenack TM, Whelan S, Curran GL, Duff KE, Poduslo JF.

Neuroscience. 2000;101(4):939-44.

PMID:
11113343
6.

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse.

Gordon MN, Holcomb LA, Jantzen PT, DiCarlo G, Wilcock D, Boyett KW, Connor K, Melachrino J, O'Callaghan JP, Morgan D.

Exp Neurol. 2002 Feb;173(2):183-95.

PMID:
11822882
7.

Advanced glycation endproducts and pro-inflammatory cytokines in transgenic Tg2576 mice with amyloid plaque pathology.

Münch G, Apelt J, Rosemarie-Kientsch-Engel, Stahl P, Lüth HJ, Schliebs R.

J Neurochem. 2003 Jul;86(2):283-9.

8.

Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease.

Manczak M, Mao P, Nakamura K, Bebbington C, Park B, Reddy PH.

Hum Mol Genet. 2009 Oct 15;18(20):3876-93. doi: 10.1093/hmg/ddp331. Epub 2009 Jul 19.

9.

Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology.

Rossner S, Apelt J, Schliebs R, Perez-Polo JR, Bigl V.

J Neurosci Res. 2001 Jun 1;64(5):437-46. Erratum in: J Neurosci Res 2001 Nov 15;66(4):730.

PMID:
11391698
10.

Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.

Katsouri L, Georgopoulos S.

PLoS One. 2011;6(7):e21880. doi: 10.1371/journal.pone.0021880. Epub 2011 Jul 6.

11.

Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease.

Richardson JC, Kendal CE, Anderson R, Priest F, Gower E, Soden P, Gray R, Topps S, Howlett DR, Lavender D, Clarke NJ, Barnes JC, Haworth R, Stewart MG, Rupniak HT.

Neuroscience. 2003;122(1):213-28.

PMID:
14596862
12.

Myeloid differentiation factor 88-deficient bone marrow cells improve Alzheimer's disease-related symptoms and pathology.

Hao W, Liu Y, Liu S, Walter S, Grimm MO, Kiliaan AJ, Penke B, Hartmann T, Rübe CE, Menger MD, Fassbender K.

Brain. 2011 Jan;134(Pt 1):278-92. doi: 10.1093/brain/awq325. Epub 2010 Nov 28.

13.

beta-amyloid deposits in transgenic mice expressing human beta-amyloid precursor protein have the same characteristics as those in Alzheimer's disease.

Terai K, Iwai A, Kawabata S, Tasaki Y, Watanabe T, Miyata K, Yamaguchi T.

Neuroscience. 2001;104(2):299-310.

PMID:
11377835
14.

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

Takahashi RH, Almeida CG, Kearney PF, Yu F, Lin MT, Milner TA, Gouras GK.

J Neurosci. 2004 Apr 7;24(14):3592-9.

15.

Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent.

Hartlage-Rübsamen M, Zeitschel U, Apelt J, Gärtner U, Franke H, Stahl T, Günther A, Schliebs R, Penkowa M, Bigl V, Rossner S.

Glia. 2003 Jan 15;41(2):169-79.

PMID:
12509807
16.

Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease.

Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW.

Neuroscience. 1992 Jun;48(4):763-77.

PMID:
1378573
17.

Viral-induced inflammation is accompanied by beta-amyloid plaque reduction in brains of amyloid precursor protein transgenic Tg2576 mice.

Stahl T, Reimers C, Johne R, Schliebs R, Seeger J.

Eur J Neurosci. 2006 Oct;24(7):1923-34.

PMID:
17067295
18.

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

Tomiyama T, Matsuyama S, Iso H, Umeda T, Takuma H, Ohnishi K, Ishibashi K, Teraoka R, Sakama N, Yamashita T, Nishitsuji K, Ito K, Shimada H, Lambert MP, Klein WL, Mori H.

J Neurosci. 2010 Apr 7;30(14):4845-56. doi: 10.1523/JNEUROSCI.5825-09.2010.

19.

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.

Bales KR, Verina T, Cummins DJ, Du Y, Dodel RC, Saura J, Fishman CE, DeLong CA, Piccardo P, Petegnief V, Ghetti B, Paul SM.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15233-8.

20.

Deposition of lactoferrin in fibrillar-type senile plaques in the brains of transgenic mouse models of Alzheimer's disease.

Wang L, Sato H, Zhao S, Tooyama I.

Neurosci Lett. 2010 Sep 13;481(3):164-7. doi: 10.1016/j.neulet.2010.06.079. Epub 2010 Jul 3.

PMID:
20599473
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