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Results: 1 to 20 of 106

1.

Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning.

Lim KC, Hosoya T, Brandt W, Ku CJ, Hosoya-Ohmura S, Camper SA, Yamamoto M, Engel JD.

J Clin Invest. 2012 Oct 1;122(10):3705-17. doi: 10.1172/JCI61619. Epub 2012 Sep 10.

PMID:
22996665
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.

Johnson KD, Hsu AP, Ryu MJ, Wang J, Gao X, Boyer ME, Liu Y, Lee Y, Calvo KR, Keles S, Zhang J, Holland SM, Bresnick EH.

J Clin Invest. 2012 Oct 1;122(10):3692-704. doi: 10.1172/JCI61623. Epub 2012 Sep 10.

PMID:
22996659
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.

Khandekar M, Brandt W, Zhou Y, Dagenais S, Glover TW, Suzuki N, Shimizu R, Yamamoto M, Lim KC, Engel JD.

Development. 2007 May;134(9):1703-12. Epub 2007 Mar 29.

PMID:
17395646
[PubMed - indexed for MEDLINE]
Free Article
4.

Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells.

Wozniak RJ, Boyer ME, Grass JA, Lee Y, Bresnick EH.

J Biol Chem. 2007 May 11;282(19):14665-74. Epub 2007 Mar 7.

PMID:
17347142
[PubMed - indexed for MEDLINE]
Free Article
5.

In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis.

Göthert JR, Gustin SE, Hall MA, Green AR, Göttgens B, Izon DJ, Begley CG.

Blood. 2005 Apr 1;105(7):2724-32. Epub 2004 Dec 14.

PMID:
15598809
[PubMed - indexed for MEDLINE]
Free Article
6.

Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT.

Hoshino T, Shimizu R, Ohmori S, Nagano M, Pan X, Ohneda O, Khandekar M, Yamamoto M, Lim KC, Engel JD.

Genes Cells. 2008 Feb;13(2):159-70. doi: 10.1111/j.1365-2443.2007.01158.x.

PMID:
18233958
[PubMed - indexed for MEDLINE]
7.

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.

Yuasa H, Oike Y, Iwama A, Nishikata I, Sugiyama D, Perkins A, Mucenski ML, Suda T, Morishita K.

EMBO J. 2005 Jun 1;24(11):1976-87. Epub 2005 May 12.

PMID:
15889140
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Gata2 is required for HSC generation and survival.

de Pater E, Kaimakis P, Vink CS, Yokomizo T, Yamada-Inagawa T, van der Linden R, Kartalaei PS, Camper SA, Speck N, Dzierzak E.

J Exp Med. 2013 Dec 16;210(13):2843-50. doi: 10.1084/jem.20130751. Epub 2013 Dec 2.

PMID:
24297996
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry.

Ku CJ, Hosoya T, Maillard I, Engel JD.

Blood. 2012 Mar 8;119(10):2242-51. doi: 10.1182/blood-2011-07-366070. Epub 2012 Jan 20.

PMID:
22267605
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transcription elongation factor S-II is required for definitive hematopoiesis.

Ito T, Arimitsu N, Takeuchi M, Kawamura N, Nagata M, Saso K, Akimitsu N, Hamamoto H, Natori S, Miyajima A, Sekimizu K.

Mol Cell Biol. 2006 Apr;26(8):3194-203.

PMID:
16581793
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer.

Nottingham WT, Jarratt A, Burgess M, Speck CL, Cheng JF, Prabhakar S, Rubin EM, Li PS, Sloane-Stanley J, Kong-A-San J, de Bruijn MF.

Blood. 2007 Dec 15;110(13):4188-97. Epub 2007 Sep 6.

PMID:
17823307
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.

Kobayashi-Osaki M, Ohneda O, Suzuki N, Minegishi N, Yokomizo T, Takahashi S, Lim KC, Engel JD, Yamamoto M.

Mol Cell Biol. 2005 Aug;25(16):7005-20.

PMID:
16055713
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.

Khandekar M, Suzuki N, Lewton J, Yamamoto M, Engel JD.

Mol Cell Biol. 2004 Dec;24(23):10263-76.

PMID:
15542836
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Defining the functional boundaries of the Gata2 locus by rescue with a linked bacterial artificial chromosome transgene.

Brandt W, Khandekar M, Suzuki N, Yamamoto M, Lim KC, Engel JD.

J Biol Chem. 2008 Apr 4;283(14):8976-83. doi: 10.1074/jbc.M709364200. Epub 2008 Jan 21.

PMID:
18211891
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle.

Tipping AJ, Pina C, Castor A, Hong D, Rodrigues NP, Lazzari L, May GE, Jacobsen SE, Enver T.

Blood. 2009 Mar 19;113(12):2661-72. doi: 10.1182/blood-2008-06-161117. Epub 2009 Jan 23.

PMID:
19168794
[PubMed - indexed for MEDLINE]
Free Article
16.

Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.

Gao X, Johnson KD, Chang YI, Boyer ME, Dewey CN, Zhang J, Bresnick EH.

J Exp Med. 2013 Dec 16;210(13):2833-42. doi: 10.1084/jem.20130733. Epub 2013 Dec 2.

PMID:
24297994
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.

Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WY, Wilson NK, Landry JR, Wood AD, Kolb-Kokocinski A, Green AR, Tannahill D, Lacaud G, Kouskoff V, Göttgens B.

Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17692-7. Epub 2007 Oct 25.

PMID:
17962413
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Context-dependent function of "GATA switch" sites in vivo.

Snow JW, Trowbridge JJ, Johnson KD, Fujiwara T, Emambokus NE, Grass JA, Orkin SH, Bresnick EH.

Blood. 2011 May 5;117(18):4769-72. doi: 10.1182/blood-2010-10-313031. Epub 2011 Mar 11.

PMID:
21398579
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice.

Ainoya K, Moriguchi T, Ohmori S, Souma T, Takai J, Morita M, Chandler KJ, Mortlock DP, Shimizu R, Engel JD, Lim KC, Yamamoto M.

Mol Cell Biol. 2012 Jun;32(12):2312-22. doi: 10.1128/MCB.06699-11. Epub 2012 Apr 9.

PMID:
22493062
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

[Effect of GATA-2 overexpression on function of mouse fetal liver hematopoietic stem cells].

Wu J, Wu B, Zhang YL, Xie YY, Huang QH.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013 Aug;21(4):999-1004. doi: 10.7534/j.issn.1009-2137.2013.04.036. Chinese.

PMID:
23998601
[PubMed - indexed for MEDLINE]

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