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Results: 1 to 20 of 131

1.

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa.

Clambey ET, McNamee EN, Westrich JA, Glover LE, Campbell EL, Jedlicka P, de Zoeten EF, Cambier JC, Stenmark KR, Colgan SP, Eltzschig HK.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2784-93. doi: 10.1073/pnas.1202366109. Epub 2012 Sep 17.

PMID:
22988108
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha.

Ben-Shoshan J, Maysel-Auslender S, Mor A, Keren G, George J.

Eur J Immunol. 2008 Sep;38(9):2412-8. doi: 10.1002/eji.200838318.

PMID:
18792019
[PubMed - indexed for MEDLINE]
3.

Hypoxia-inducible factor-dependent repression of equilibrative nucleoside transporter 2 attenuates mucosal inflammation during intestinal hypoxia.

Morote-Garcia JC, Rosenberger P, Nivillac NM, Coe IR, Eltzschig HK.

Gastroenterology. 2009 Feb;136(2):607-18. doi: 10.1053/j.gastro.2008.10.037. Epub 2008 Nov 1.

PMID:
19105964
[PubMed - indexed for MEDLINE]
4.

Activation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitis.

Singh NP, Singh UP, Singh B, Price RL, Nagarkatti M, Nagarkatti PS.

PLoS One. 2011;6(8):e23522. doi: 10.1371/journal.pone.0023522. Epub 2011 Aug 15.

PMID:
21858153
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Transient local depletion of Foxp3+ regulatory T cells during recovery from colitis via Fas/Fas ligand-induced death.

Reardon C, Wang A, McKay DM.

J Immunol. 2008 Jun 15;180(12):8316-26.

PMID:
18523298
[PubMed - indexed for MEDLINE]
Free Article
6.

Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.

Takimoto T, Wakabayashi Y, Sekiya T, Inoue N, Morita R, Ichiyama K, Takahashi R, Asakawa M, Muto G, Mori T, Hasegawa E, Saika S, Hara T, Nomura M, Yoshimura A.

J Immunol. 2010 Jul 15;185(2):842-55. doi: 10.4049/jimmunol.0904100. Epub 2010 Jun 14. Erratum in: J Immunol. 2011 Jan 1;186(1):632. Shizuya, Saika [corrected to Saika, Shizuya].

PMID:
20548029
[PubMed - indexed for MEDLINE]
Free Article
7.

DNA methylation controls Foxp3 gene expression.

Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J.

Eur J Immunol. 2008 Jun;38(6):1654-63. doi: 10.1002/eji.200838105.

PMID:
18493985
[PubMed - indexed for MEDLINE]
8.

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

Fantini MC, Rizzo A, Fina D, Caruso R, Sarra M, Stolfi C, Becker C, Macdonald TT, Pallone F, Neurath MF, Monteleone G.

Gastroenterology. 2009 Apr;136(4):1308-16, e1-3. doi: 10.1053/j.gastro.2008.12.053. Epub 2008 Dec 27.

PMID:
19192480
[PubMed - indexed for MEDLINE]
9.

Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.

Karhausen J, Furuta GT, Tomaszewski JE, Johnson RS, Colgan SP, Haase VH.

J Clin Invest. 2004 Oct;114(8):1098-106.

PMID:
15489957
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

[Hypoxia and its simulant CoCl(2) down-regulates Foxp3 expression independent from HIF-1alpha].

Wang XD, Liu CX, Wu YL, Chen J.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Jun;17(3):533-6. Chinese.

PMID:
19549358
[PubMed - indexed for MEDLINE]
11.

Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.

Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D.

J Immunol. 2010 Nov 15;185(10):6306-16. doi: 10.4049/jimmunol.1002541. Epub 2010 Oct 13.

PMID:
20943999
[PubMed - indexed for MEDLINE]
Free Article
12.

HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation.

Zampell JC, Yan A, Avraham T, Daluvoy S, Weitman ES, Mehrara BJ.

FASEB J. 2012 Mar;26(3):1027-39. doi: 10.1096/fj.11-195321. Epub 2011 Nov 8.

PMID:
22067482
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

IκB(NS) protein mediates regulatory T cell development via induction of the Foxp3 transcription factor.

Schuster M, Glauben R, Plaza-Sirvent C, Schreiber L, Annemann M, Floess S, Kühl AA, Clayton LK, Sparwasser T, Schulze-Osthoff K, Pfeffer K, Huehn J, Siegmund B, Schmitz I.

Immunity. 2012 Dec 14;37(6):998-1008. doi: 10.1016/j.immuni.2012.08.023. Epub 2012 Nov 29.

PMID:
23200824
[PubMed - indexed for MEDLINE]
Free Article
14.

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.

Shi LZ, Wang R, Huang G, Vogel P, Neale G, Green DR, Chi H.

J Exp Med. 2011 Jul 4;208(7):1367-76. doi: 10.1084/jem.20110278. Epub 2011 Jun 27.

PMID:
21708926
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

CD4+FoxP3+ regulatory T cells from Gαi2-/- mice are functionally active in vitro, but do not prevent colitis.

Götlind YY, Raghavan S, Bland PW, Hörnquist EH.

PLoS One. 2011;6(9):e25073. doi: 10.1371/journal.pone.0025073. Epub 2011 Sep 22.

PMID:
21966415
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Induction of CD36 and thrombospondin-1 in macrophages by hypoxia-inducible factor 1 and its relevance in the inflammatory process.

Ortiz-Masià D, Díez I, Calatayud S, Hernández C, Cosín-Roger J, Hinojosa J, Esplugues JV, Barrachina MD.

PLoS One. 2012;7(10):e48535. doi: 10.1371/journal.pone.0048535. Epub 2012 Oct 31.

PMID:
23119050
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cutting edge: trans-signaling via the soluble IL-6R abrogates the induction of FoxP3 in naive CD4+CD25 T cells.

Dominitzki S, Fantini MC, Neufert C, Nikolaev A, Galle PR, Scheller J, Monteleone G, Rose-John S, Neurath MF, Becker C.

J Immunol. 2007 Aug 15;179(4):2041-5.

PMID:
17675459
[PubMed - indexed for MEDLINE]
Free Article
18.

IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo.

Chen Q, Kim YC, Laurence A, Punkosdy GA, Shevach EM.

J Immunol. 2011 Jun 1;186(11):6329-37. doi: 10.4049/jimmunol.1100061. Epub 2011 Apr 27.

PMID:
21525380
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Role of hypoxia-inducible factor-1α expression in regulatory T cells on nasal polypogenesis.

Jin J, Chang DY, Kim SH, Rha KS, Mo JH, Shin EC, Kim YM.

Laryngoscope. 2014 May;124(5):E151-9. doi: 10.1002/lary.24472. Epub 2013 Dec 11.

PMID:
24142705
[PubMed - indexed for MEDLINE]
20.

T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2.

Koch MA, Thomas KR, Perdue NR, Smigiel KS, Srivastava S, Campbell DJ.

Immunity. 2012 Sep 21;37(3):501-10. doi: 10.1016/j.immuni.2012.05.031. Epub 2012 Sep 6.

PMID:
22960221
[PubMed - indexed for MEDLINE]
Free PMC Article
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