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Results: 1 to 20 of 114

1.

Insights towards sulfonamide drug specificity in α-carbonic anhydrases.

Aggarwal M, Kondeti B, McKenna R.

Bioorg Med Chem. 2013 Mar 15;21(6):1526-33. doi: 10.1016/j.bmc.2012.08.019. Epub 2012 Aug 28.

PMID:
22985956
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.

Pinard MA, Boone CD, Rife BD, Supuran CT, McKenna R.

Bioorg Med Chem. 2013 Nov 15;21(22):7210-5. doi: 10.1016/j.bmc.2013.08.033. Epub 2013 Aug 28.

PMID:
24090602
[PubMed - indexed for MEDLINE]
3.

Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides.

Akdemir A, Güzel-Akdemir O, Scozzafava A, Capasso C, Supuran CT.

Bioorg Med Chem. 2013 Sep 1;21(17):5228-32. doi: 10.1016/j.bmc.2013.06.029. Epub 2013 Jun 20.

PMID:
23842519
[PubMed - indexed for MEDLINE]
4.

S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.

Lopez M, Paul B, Hofmann A, Morizzi J, Wu QK, Charman SA, Innocenti A, Vullo D, Supuran CT, Poulsen SA.

J Med Chem. 2009 Oct 22;52(20):6421-32. doi: 10.1021/jm900914e.

PMID:
19827837
[PubMed - indexed for MEDLINE]
5.

5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.

Leitans J, Sprudza A, Tanc M, Vozny I, Zalubovskis R, Tars K, Supuran CT.

Bioorg Med Chem. 2013 Sep 1;21(17):5130-8. doi: 10.1016/j.bmc.2013.06.041. Epub 2013 Jun 27.

PMID:
23859774
[PubMed - indexed for MEDLINE]
6.

Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?

Temperini C, Cecchi A, Scozzafava A, Supuran CT.

Org Biomol Chem. 2008 Jul 21;6(14):2499-506. doi: 10.1039/b800767e. Epub 2008 May 29.

PMID:
18600270
[PubMed - indexed for MEDLINE]
7.

Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.

Knaus EE, Innocenti A, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett. 2011 Oct 1;21(19):5892-6. doi: 10.1016/j.bmcl.2011.07.090. Epub 2011 Jul 30.

PMID:
21852133
[PubMed - indexed for MEDLINE]
8.

Carbonic anhydrases: current state of the art, therapeutic applications and future prospects.

Pastorekova S, Parkkila S, Pastorek J, Supuran CT.

J Enzyme Inhib Med Chem. 2004 Jun;19(3):199-229. Review.

PMID:
15499993
[PubMed - indexed for MEDLINE]
9.

Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII.

Guler OO, De Simone G, Supuran CT.

Curr Med Chem. 2010;17(15):1516-26. Review.

PMID:
20166929
[PubMed - indexed for MEDLINE]
10.

Indanesulfonamides as carbonic anhydrase inhibitors. Toward structure-based design of selective inhibitors of the tumor-associated isozyme CA IX.

Thiry A, Ledecq M, Cecchi A, Dogné JM, Wouters J, Supuran CT, Masereel B.

J Med Chem. 2006 May 4;49(9):2743-9.

PMID:
16640335
[PubMed - indexed for MEDLINE]
11.

Update on carbonic anhydrase inhibitors: a patent review (2008 - 2011).

Aggarwal M, McKenna R.

Expert Opin Ther Pat. 2012 Aug;22(8):903-15. doi: 10.1517/13543776.2012.707646. Epub 2012 Jul 13. Review.

PMID:
22788994
[PubMed - indexed for MEDLINE]
12.

Dissecting the inhibition mechanism of cytosolic versus transmembrane carbonic anhydrases by ESR.

Ciani L, Cecchi A, Temperini C, Supuran CT, Ristori S.

J Phys Chem B. 2009 Oct 22;113(42):13998-4005. doi: 10.1021/jp906593c.

PMID:
19778001
[PubMed - indexed for MEDLINE]
13.

Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.

Cecchi A, Hulikova A, Pastorek J, Pastoreková S, Scozzafava A, Winum JY, Montero JL, Supuran CT.

J Med Chem. 2005 Jul 28;48(15):4834-41.

PMID:
16033263
[PubMed - indexed for MEDLINE]
14.

o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII.

Güzel-Akdemir Ö, Akdemir A, Isik S, Vullo D, Supuran CT.

Bioorg Med Chem. 2013 Mar 15;21(6):1386-91. doi: 10.1016/j.bmc.2012.12.037. Epub 2013 Jan 4.

PMID:
23352754
[PubMed - indexed for MEDLINE]
15.

Structure, function and applications of carbonic anhydrase isozymes.

Imtaiyaz Hassan M, Shajee B, Waheed A, Ahmad F, Sly WS.

Bioorg Med Chem. 2013 Mar 15;21(6):1570-82. doi: 10.1016/j.bmc.2012.04.044. Epub 2012 Apr 27. Review.

PMID:
22607884
[PubMed - indexed for MEDLINE]
16.

Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.

Weber A, Casini A, Heine A, Kuhn D, Supuran CT, Scozzafava A, Klebe G.

J Med Chem. 2004 Jan 29;47(3):550-7.

PMID:
14736236
[PubMed - indexed for MEDLINE]
17.

Carbonic anhydrases as drug targets--an overview.

Supuran CT.

Curr Top Med Chem. 2007;7(9):825-33. Review.

PMID:
17504127
[PubMed - indexed for MEDLINE]
18.

Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.

Saczewski F, Innocenti A, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Scozzafava A, Temperini C, Supuran CT.

Bioorg Med Chem. 2008 Apr 1;16(7):3933-40. doi: 10.1016/j.bmc.2008.01.034. Epub 2008 Jan 26.

PMID:
18242998
[PubMed - indexed for MEDLINE]
19.

Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.

Güzel O, Temperini C, Innocenti A, Scozzafava A, Salman A, Supuran CT.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):152-8. Epub 2007 Nov 4.

PMID:
18024029
[PubMed - indexed for MEDLINE]
20.

Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV.

Gavernet L, Gonzalez Funes JL, Palestro PH, Bruno Blanch LE, Estiu GL, Maresca A, Barrios I, Supuran CT.

Bioorg Med Chem. 2013 Mar 15;21(6):1410-8. doi: 10.1016/j.bmc.2012.10.048. Epub 2012 Nov 29.

PMID:
23266178
[PubMed - indexed for MEDLINE]

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