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Results: 1 to 20 of 89

1.

Molecular docking and dynamics simulations of A.niger RNase from Aspergillus niger ATCC26550: for potential prevention of human cancer.

Kumar GR, Chikati R, Pandrangi SL, Kandapal M, Sonkar K, Gupta N, Mulakayala C, Jagannadham MV, Kumar CS, Saxena S, Das MD.

J Mol Model. 2013 Feb;19(2):613-21. doi: 10.1007/s00894-012-1587-9. Epub 2012 Sep 16.

PMID:
22983653
[PubMed - indexed for MEDLINE]
2.

Protein-protein docking on molecular models of Aspergillus niger RNase and human actin: novel target for anticancer therapeutics.

Gundampati RK, Chikati R, Kumari M, Sharma A, Pratyush DD, Jagannadham MV, Kumar CS, Debnath Das M.

J Mol Model. 2012 Feb;18(2):653-62. doi: 10.1007/s00894-011-1078-4. Epub 2011 May 12.

PMID:
21562828
[PubMed - indexed for MEDLINE]
3.

The 1.8 Å crystal structure of ACTIBIND suggests a mode of action for T2 ribonucleases as antitumorigenic agents.

de Leeuw M, González A, Lanir A, Roiz L, Smirnoff P, Schwartz B, Shoseyov O, Almog O.

J Med Chem. 2012 Feb 9;55(3):1013-20. doi: 10.1021/jm1015507. Epub 2012 Jan 31.

PMID:
22216760
[PubMed - indexed for MEDLINE]
4.

Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action.

Wang S, Liu Q, Zhang Y, Liu K, Yu P, Liu K, Luan J, Duan H, Lu Z, Wang F, Wu E, Yagasaki K, Zhang G.

Mol Cancer. 2009 Oct 1;8:81. doi: 10.1186/1476-4598-8-81.

PMID:
19796390
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

ACTIBIND, an actin-binding fungal T2-RNase with antiangiogenic and anticarcinogenic characteristics.

Roiz L, Smirnoff P, Bar-Eli M, Schwartz B, Shoseyov O.

Cancer. 2006 May 15;106(10):2295-308.

PMID:
16586499
[PubMed - indexed for MEDLINE]
Free Article
6.

Purification and partial characterization of an extracellular ribonuclease from a mutant of Aspergillus niger.

Xiong YH, Liu JZ, Song HY.

Appl Biochem Biotechnol. 2005 Jun;125(3):201-10.

PMID:
15917583
[PubMed - indexed for MEDLINE]
7.

Evaluation of protein-protein docking model structures using all-atom molecular dynamics simulations combined with the solution theory in the energy representation.

Takemura K, Guo H, Sakuraba S, Matubayasi N, Kitao A.

J Chem Phys. 2012 Dec 7;137(21):215105. doi: 10.1063/1.4768901.

PMID:
23231264
[PubMed - indexed for MEDLINE]
8.

Equilibrium unfolding of A. niger RNase: pH dependence of chemical and thermal denaturation.

Kumar GR, Sharma A, Kumari M, Jagannadham MV, Debnath M.

Eur Biophys J. 2011 Aug;40(8):923-35. doi: 10.1007/s00249-011-0708-1. Epub 2011 May 25.

PMID:
21611854
[PubMed - indexed for MEDLINE]
9.

N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.

Baviskar AT, Madaan C, Preet R, Mohapatra P, Jain V, Agarwal A, Guchhait SK, Kundu CN, Banerjee UC, Bharatam PV.

J Med Chem. 2011 Jul 28;54(14):5013-30. doi: 10.1021/jm200235u. Epub 2011 Jun 23.

PMID:
21644529
[PubMed - indexed for MEDLINE]
10.

Purification, kinetic and thermodynamic studies of a new ribonuclease from a mutant of Aspergillus niger.

Xiong YH, Liu JZ, Song HY, Ji LN.

J Biotechnol. 2005 Oct 10;119(4):348-56.

PMID:
15946756
[PubMed - indexed for MEDLINE]
11.

Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer.

Wang N, Wang ZY, Mo SL, Loo TY, Wang DM, Luo HB, Yang DP, Chen YL, Shen JG, Chen JP.

Breast Cancer Res Treat. 2012 Aug;134(3):943-55. doi: 10.1007/s10549-012-1977-9. Epub 2012 Feb 21.

PMID:
22350787
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Development of peptide inhibitor as a therapeutic agent against head and neck squamous cell carcinoma (HNSCC) targeting p38alpha MAP kinase.

Gill K, Singh AK, Kapoor V, Nigam L, Kumar R, Holla P, Das SN, Yadav S, Subbarao N, Mohanti BK, Dey S.

Biochim Biophys Acta. 2013 Mar;1830(3):2763-9.

PMID:
23238519
[PubMed - indexed for MEDLINE]
13.

Characterization of the activities of actin-affecting drugs on tumor cell migration.

Hayot C, Debeir O, Van Ham P, Van Damme M, Kiss R, Decaestecker C.

Toxicol Appl Pharmacol. 2006 Feb 15;211(1):30-40. Epub 2005 Jul 11.

PMID:
16005926
[PubMed - indexed for MEDLINE]
14.

PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo.

Ma JG, Huang H, Chen SM, Chen Y, Xin XL, Lin LP, Ding J, Liu H, Meng LH.

Breast Cancer Res Treat. 2011 Nov;130(1):85-96. doi: 10.1007/s10549-010-1302-4. Epub 2010 Dec 22.

PMID:
21181437
[PubMed - indexed for MEDLINE]
15.

The role of electrostatic interactions in the antitumor activity of dimeric RNases.

Notomista E, Mancheño JM, Crescenzi O, Di Donato A, Gavilanes J, D'Alessio G.

FEBS J. 2006 Aug;273(16):3687-97.

PMID:
16911519
[PubMed - indexed for MEDLINE]
16.

An inverse docking approach for identifying new potential anti-cancer targets.

Grinter SZ, Liang Y, Huang SY, Hyder SM, Zou X.

J Mol Graph Model. 2011 Apr;29(6):795-9. doi: 10.1016/j.jmgm.2011.01.002. Epub 2011 Jan 19.

PMID:
21315634
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Endo- and exo-inulinases: enzyme-substrate interaction and rational immobilization.

Basso A, Spizzo P, Ferrario V, Knapic L, Savko N, Braiuca P, Ebert C, Ricca E, Calabrò V, Gardossi L.

Biotechnol Prog. 2010 Mar-Apr;26(2):397-405. doi: 10.1002/btpr.334.

PMID:
19941325
[PubMed - indexed for MEDLINE]
18.

Epidermal growth factor receptor-dependent cytotoxic effect by an EGF-ribonuclease conjugate on human cancer cell lines--a trial for less immunogenic chimeric toxin.

Jinno H, Ueda M, Ozawa S, Kikuchi K, Ikeda T, Enomoto K, Kitajima M.

Cancer Chemother Pharmacol. 1996;38(4):303-8.

PMID:
8674151
[PubMed - indexed for MEDLINE]
19.

RNase MC2: a new Momordica charantia ribonuclease that induces apoptosis in breast cancer cells associated with activation of MAPKs and induction of caspase pathways.

Fang EF, Zhang CZ, Fong WP, Ng TB.

Apoptosis. 2012 Apr;17(4):377-87. doi: 10.1007/s10495-011-0684-z.

PMID:
22134530
[PubMed - indexed for MEDLINE]
20.

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