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Results: 1 to 20 of 111

1.

LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation.

Rouquette-Jazdanian AK, Sommers CL, Kortum RL, Morrison DK, Samelson LE.

Mol Cell. 2012 Oct 26;48(2):298-312. doi: 10.1016/j.molcel.2012.08.011. Epub 2012 Sep 13.

PMID:
22981863
[PubMed - indexed for MEDLINE]
Free PMC Article
2.
3.

Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line.

Irvin BJ, Williams BL, Nilson AE, Maynor HO, Abraham RT.

Mol Cell Biol. 2000 Dec;20(24):9149-61.

PMID:
11094067
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1.

Phee H, Abraham RT, Weiss A.

Nat Immunol. 2005 Jun;6(6):608-17. Epub 2005 May 1.

PMID:
15864311
[PubMed - indexed for MEDLINE]
5.

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling.

Zhang W, Trible RP, Zhu M, Liu SK, McGlade CJ, Samelson LE.

J Biol Chem. 2000 Jul 28;275(30):23355-61.

PMID:
10811803
[PubMed - indexed for MEDLINE]
Free Article
6.

T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.

Gonen R, Beach D, Ainey C, Yablonski D.

J Biol Chem. 2005 Mar 4;280(9):8364-70. Epub 2004 Dec 28.

PMID:
15623534
[PubMed - indexed for MEDLINE]
Free Article
7.

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.

Williams BL, Irvin BJ, Sutor SL, Chini CC, Yacyshyn E, Bubeck Wardenburg J, Dalton M, Chan AC, Abraham RT.

EMBO J. 1999 Apr 1;18(7):1832-44.

PMID:
10202147
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Phospholipase activity of phospholipase C-gamma1 is required for nerve growth factor-regulated MAP kinase signaling cascade in PC12 cells.

Rong R, Ahn JY, Chen P, Suh PG, Ye K.

J Biol Chem. 2003 Dec 26;278(52):52497-503. Epub 2003 Oct 21.

PMID:
14570902
[PubMed - indexed for MEDLINE]
Free Article
9.

Direct interaction of SOS1 Ras exchange protein with the SH3 domain of phospholipase C-gamma1.

Kim MJ, Chang JS, Park SK, Hwang JI, Ryu SH, Suh PG.

Biochemistry. 2000 Jul 25;39(29):8674-82.

PMID:
10913276
[PubMed - indexed for MEDLINE]
10.

70Z/3 Cbl induces PLC gamma 1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism.

Graham LJ, Verí MC, DeBell KE, Noviello C, Rawat R, Jen S, Bonvini E, Rellahan B.

Oncogene. 2003 Apr 24;22(16):2493-503.

PMID:
12717426
[PubMed - indexed for MEDLINE]
11.

Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice.

Miyaji M, Kortum RL, Surana R, Li W, Woolard KD, Simpson RM, Samelson LE, Sommers CL.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14502-7. doi: 10.1073/pnas.0903894106. Epub 2009 Aug 10.

PMID:
19667175
[PubMed - indexed for MEDLINE]
Free PMC Article
12.
13.

Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells.

Shin KS, Shin EY, Lee CS, Quan SH, Woo KN, Soung NK, Kwak SJ, Kim SR, Kim EG.

Exp Mol Med. 2002 May 31;34(2):172-6.

PMID:
12085993
[PubMed - indexed for MEDLINE]
Free Article
14.

The B lymphocyte adaptor molecule of 32 kD (Bam32) regulates B cell antigen receptor signaling and cell survival.

Niiro H, Maeda A, Kurosaki T, Clark EA.

J Exp Med. 2002 Jan 7;195(1):143-9.

PMID:
11781373
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses.

Kremer KN, Clift IC, Miamen AG, Bamidele AO, Qian NX, Humphreys TD, Hedin KE.

J Immunol. 2011 Aug 1;187(3):1440-7. doi: 10.4049/jimmunol.1100820. Epub 2011 Jun 24.

PMID:
21705626
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.

Ku GM, Yablonski D, Manser E, Lim L, Weiss A.

EMBO J. 2001 Feb 1;20(3):457-65.

PMID:
11157752
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation.

Shan X, Balakir R, Criado G, Wood JS, Seminario MC, Madrenas J, Wange RL.

Mol Cell Biol. 2001 Nov;21(21):7137-49.

PMID:
11585897
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

p21-activated kinase 1 (PAK1) can promote ERK activation in a kinase-independent manner.

Wang Z, Fu M, Wang L, Liu J, Li Y, Brakebusch C, Mei Q.

J Biol Chem. 2013 Jul 5;288(27):20093-9. doi: 10.1074/jbc.M112.426023. Epub 2013 May 7.

PMID:
23653349
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.

Li M, Ong SS, Rajwa B, Thieu VT, Geahlen RL, Harrison ML.

Mol Cell Biol. 2008 Jan;28(2):630-41. Epub 2007 Nov 12.

PMID:
17998336
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade.

Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ.

J Biol Chem. 2000 Jan 21;275(3):2219-30.

PMID:
10636929
[PubMed - indexed for MEDLINE]
Free Article

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