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Items: 1 to 20 of 210

1.

Kinetic modeling of human hepatic glucose metabolism in type 2 diabetes mellitus predicts higher risk of hypoglycemic events in rigorous insulin therapy.

König M, Holzhütter HG.

J Biol Chem. 2012 Oct 26;287(44):36978-89. doi: 10.1074/jbc.M112.382069. Epub 2012 Sep 12.

2.

Quantifying the contribution of the liver to glucose homeostasis: a detailed kinetic model of human hepatic glucose metabolism.

König M, Bulik S, Holzhütter HG.

PLoS Comput Biol. 2012;8(6):e1002577. doi: 10.1371/journal.pcbi.1002577. Epub 2012 Jun 21.

3.

Catecholamine responses and their interactions with other glucoregulatory hormones.

Vranic M, Gauthier C, Bilinski D, Wasserman D, El Tayeb K, Hetenyi G Jr, Lickley HL.

Am J Physiol. 1984 Aug;247(2 Pt 1):E145-56.

PMID:
6147092
4.

Role of hepatic glycogen breakdown in defective counterregulation of hypoglycemia in intensively treated type 1 diabetes.

Kishore P, Gabriely I, Cui MH, Di Vito J, Gajavelli S, Hwang JH, Shamoon H.

Diabetes. 2006 Mar;55(3):659-66.

5.

Multiple defects in counterregulation of hypoglycemia in modestly advanced type 2 diabetes mellitus.

Israelian Z, Szoke E, Woerle J, Bokhari S, Schorr M, Schwenke DC, Cryer PE, Gerich JE, Meyer C.

Metabolism. 2006 May;55(5):593-8.

PMID:
16631434
6.

Regulation of carbohydrate metabolism and response to hypoglycemia.

Butler PC, Rizza RA.

Endocrinol Metab Clin North Am. 1989 Mar;18(1):1-25. Review.

PMID:
2645121
7.

Dose selection using a semi-mechanistic integrated glucose-insulin-glucagon model: designing phase 2 trials for a novel oral glucokinase activator.

Zhang X, Schneck K, Bue-Valleskey J, Yeo KP, Heathman M, Sinha V.

J Pharmacokinet Pharmacodyn. 2013 Feb;40(1):53-65. doi: 10.1007/s10928-012-9286-9. Epub 2012 Dec 22.

PMID:
23263772
8.

Increased epinephrine and skeletal muscle responses to hypoglycemia in non-insulin-dependent diabetes mellitus.

Shamoon H, Friedman S, Canton C, Zacharowicz L, Hu M, Rossetti L.

J Clin Invest. 1994 Jun;93(6):2562-71.

9.

Counterregulation during spontaneous nocturnal hypoglycemia in prepubertal children with type 1 diabetes.

Matyka KA, Crowne EC, Havel PJ, Macdonald IA, Matthews D, Dunger DB.

Diabetes Care. 1999 Jul;22(7):1144-50.

10.

Insulin sensitively controls the glucagon response to mild hypoglycemia in the dog.

Igawa K, Mugavero M, Shiota M, Neal DW, Cherrington AD.

Diabetes. 2002 Oct;51(10):3033-42.

11.

Glucose regulation in non-insulin-dependent diabetes mellitus. Interaction between pancreatic islets and the liver.

Halter JB, Ward WK, Porte D Jr, Best JD, Pfeifer MA.

Am J Med. 1985 Aug 23;79(2B):6-12. Review.

PMID:
2863979
12.

Role of gluconeogenesis in sustaining glucose production during hypoglycemia caused by continuous insulin infusion in conscious dogs.

Frizzell RT, Hendrick GK, Biggers DW, Lacy DB, Donahue DP, Green DR, Carr RK, Williams PE, Stevenson RW, Cherrington AD.

Diabetes. 1988 Jun;37(6):749-59.

PMID:
3289995
13.

Hormonal and metabolic counterregulation during and after high-dose insulin-induced hypoglycemia in diabetes mellitus type 2.

Bischof MG, Ludwig C, Hofer A, Kletter K, Krebs M, Stingl H, Nowotny P, Waldhäusl W, Roden M.

Horm Metab Res. 2000 Oct;32(10):417-23.

PMID:
11069207
14.

Counterregulation by epinephrine and glucagon during insulin-induced hypoglycemia in the conscious dog.

Connolly CC, Ivy RE, Adkins-Marshall BA, Dobbins RL, Neal DW, Williams PE, Cherrington AD.

Diabetes Res Clin Pract. 1996 Mar;31(1-3):45-56.

PMID:
8792101
15.

Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy.

Rizza RA.

Diabetes. 2010 Nov;59(11):2697-707. doi: 10.2337/db10-1032. Epub 2010 Aug 12.

16.

Effect of continuous subcutaneous insulin infusion with lispro on hepatic responsiveness to glucagon in type 1 diabetes.

Launay B, Zinman B, Tildesley HD, Strack T, Chiasson JL.

Diabetes Care. 1998 Oct;21(10):1627-31.

PMID:
9773721
17.

Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial.

Maggs DG, Buchanan TA, Burant CF, Cline G, Gumbiner B, Hsueh WA, Inzucchi S, Kelley D, Nolan J, Olefsky JM, Polonsky KS, Silver D, Valiquett TR, Shulman GI.

Ann Intern Med. 1998 Feb 1;128(3):176-85.

PMID:
9454525
18.

Effects of short-term improvement of insulin treatment and glycemia on hepatic glycogen metabolism in type 1 diabetes.

Bischof MG, Krssak M, Krebs M, Bernroider E, Stingl H, Waldhäusl W, Roden M.

Diabetes. 2001 Feb;50(2):392-8.

19.

Impact of glucagon response on postprandial hyperglycemia in men with impaired glucose tolerance and type 2 diabetes mellitus.

Henkel E, Menschikowski M, Koehler C, Leonhardt W, Hanefeld M.

Metabolism. 2005 Sep;54(9):1168-73.

PMID:
16125528
20.

Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalities.

Resmini E, Minuto F, Colao A, Ferone D.

Acta Diabetol. 2009 Jun;46(2):85-95. doi: 10.1007/s00592-009-0112-9. Epub 2009 Mar 26. Review.

PMID:
19322513
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