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Results: 1 to 20 of 114

1.

Effects of dietary fucoxanthin on cholesterol metabolism in diabetic/obese KK-A(y) mice.

Beppu F, Hosokawa M, Niwano Y, Miyashita K.

Lipids Health Dis. 2012 Sep 10;11:112. doi: 10.1186/1476-511X-11-112.

PMID:
22962999
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/obese KK-Ay mice.

Hosokawa M, Miyashita T, Nishikawa S, Emi S, Tsukui T, Beppu F, Okada T, Miyashita K.

Arch Biochem Biophys. 2010 Dec 1;504(1):17-25. doi: 10.1016/j.abb.2010.05.031. Epub 2010 May 31.

PMID:
20515643
[PubMed - indexed for MEDLINE]
3.

Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice.

Maeda H, Hosokawa M, Sashima T, Miyashita K.

J Agric Food Chem. 2007 Sep 19;55(19):7701-6. Epub 2007 Aug 23.

PMID:
17715888
[PubMed - indexed for MEDLINE]
4.

Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression.

Duan Y, Chen Y, Hu W, Li X, Yang X, Zhou X, Yin Z, Kong D, Yao Z, Hajjar DP, Liu L, Liu Q, Han J.

J Biol Chem. 2012 Jul 6;287(28):23667-77. doi: 10.1074/jbc.M112.350181. Epub 2012 May 16.

PMID:
22593575
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Down-regulation of hepatic stearoyl-CoA desaturase-1 expression by fucoxanthin via leptin signaling in diabetic/obese KK-A(y) mice.

Beppu F, Hosokawa M, Yim MJ, Shinoda T, Miyashita K.

Lipids. 2013 May;48(5):449-55. doi: 10.1007/s11745-013-3784-4. Epub 2013 Mar 21.

PMID:
23516000
[PubMed - indexed for MEDLINE]
6.

Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters.

Wu M, Dong B, Cao A, Li H, Liu J.

Atherosclerosis. 2012 Oct;224(2):401-10. doi: 10.1016/j.atherosclerosis.2012.08.012. Epub 2012 Aug 24.

PMID:
22954675
[PubMed - indexed for MEDLINE]
7.

Anti-obese property of fucoxanthin is partly mediated by altering lipid-regulating enzymes and uncoupling proteins of visceral adipose tissue in mice.

Woo MN, Jeon SM, Shin YC, Lee MK, Kang MA, Choi MS.

Mol Nutr Food Res. 2009 Dec;53(12):1603-11. doi: 10.1002/mnfr.200900079.

PMID:
19842104
[PubMed - indexed for MEDLINE]
8.

Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver.

Sun X, Essalmani R, Day R, Khatib AM, Seidah NG, Prat A.

Neoplasia. 2012 Dec;14(12):1122-31.

PMID:
23308045
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Decreased APOE-containing HDL subfractions and cholesterol efflux capacity of serum in mice lacking Pcsk9.

Choi S, Aljakna A, Srivastava U, Peterson BR, Deng B, Prat A, Korstanje R.

Lipids Health Dis. 2013 Jul 24;12:112. doi: 10.1186/1476-511X-12-112.

PMID:
23883163
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes.

Zhang L, McCabe T, Condra JH, Ni YG, Peterson LB, Wang W, Strack AM, Wang F, Pandit S, Hammond H, Wood D, Lewis D, Rosa R, Mendoza V, Cumiskey AM, Johns DG, Hansen BC, Shen X, Geoghagen N, Jensen K, Zhu L, Wietecha K, Wisniewski D, Huang L, Zhao JZ, Ernst R, Hampton R, Haytko P, Ansbro F, Chilewski S, Chin J, Mitnaul LJ, Pellacani A, Sparrow CP, An Z, Strohl W, Hubbard B, Plump AS, Blom D, Sitlani A.

Int J Biol Sci. 2012;8(3):310-27. doi: 10.7150/ijbs.3524. Epub 2012 Feb 9.

PMID:
22355267
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Function and distribution of circulating human PCSK9 expressed extrahepatically in transgenic mice.

Luo Y, Warren L, Xia D, Jensen H, Sand T, Petras S, Qin W, Miller KS, Hawkins J.

J Lipid Res. 2009 Aug;50(8):1581-8. doi: 10.1194/jlr.M800542-JLR200. Epub 2008 Dec 6.

PMID:
19060325
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters.

Dong B, Wu M, Li H, Kraemer FB, Adeli K, Seidah NG, Park SW, Liu J.

J Lipid Res. 2010 Jun;51(6):1486-95. doi: 10.1194/jlr.M003566. Epub 2010 Jan 4.

PMID:
20048381
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration.

Zaid A, Roubtsova A, Essalmani R, Marcinkiewicz J, Chamberland A, Hamelin J, Tremblay M, Jacques H, Jin W, Davignon J, Seidah NG, Prat A.

Hepatology. 2008 Aug;48(2):646-54. doi: 10.1002/hep.22354.

PMID:
18666258
[PubMed - indexed for MEDLINE]
14.

Effect of Porphyromonas gingivalis infection on post-transcriptional regulation of the low-density lipoprotein receptor in mice.

Miyazawa H, Tabeta K, Miyauchi S, Aoki-Nonaka Y, Domon H, Honda T, Nakajima T, Yamazaki K.

Lipids Health Dis. 2012 Sep 19;11:121. doi: 10.1186/1476-511X-11-121.

PMID:
22992388
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Antiobesity effects of Undaria lipid capsules prepared with scallop phospholipids.

Okada T, Mizuno Y, Sibayama S, Hosokawa M, Miyashita K.

J Food Sci. 2011 Jan-Feb;76(1):H2-6. doi: 10.1111/j.1750-3841.2010.01878.x. Epub 2010 Nov 4.

PMID:
21535684
[PubMed - indexed for MEDLINE]
16.

Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels.

Ferri N, Tibolla G, Pirillo A, Cipollone F, Mezzetti A, Pacia S, Corsini A, Catapano AL.

Atherosclerosis. 2012 Feb;220(2):381-6. doi: 10.1016/j.atherosclerosis.2011.11.026. Epub 2011 Nov 25.

PMID:
22176652
[PubMed - indexed for MEDLINE]
17.

Combination of fucoxanthin and conjugated linoleic acid attenuates body weight gain and improves lipid metabolism in high-fat diet-induced obese rats.

Hu X, Li Y, Li C, Fu Y, Cai F, Chen Q, Li D.

Arch Biochem Biophys. 2012 Mar 1;519(1):59-65. doi: 10.1016/j.abb.2012.01.011. Epub 2012 Jan 26.

PMID:
22289788
[PubMed - indexed for MEDLINE]
18.

Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.

Lipari MT, Li W, Moran P, Kong-Beltran M, Sai T, Lai J, Lin SJ, Kolumam G, Zavala-Solorio J, Izrael-Tomasevic A, Arnott D, Wang J, Peterson AS, Kirchhofer D.

J Biol Chem. 2012 Dec 21;287(52):43482-91. doi: 10.1074/jbc.M112.380618. Epub 2012 Nov 7.

PMID:
23135270
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Transintestinal cholesterol excretion is an active metabolic process modulated by PCSK9 and statin involving ABCB1.

Le May C, Berger JM, Lespine A, Pillot B, Prieur X, Letessier E, Hussain MM, Collet X, Cariou B, Costet P.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1484-93. doi: 10.1161/ATVBAHA.112.300263. Epub 2013 Apr 4.

PMID:
23559630
[PubMed - indexed for MEDLINE]
Free Article
20.

FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 (Pcsk9) gene expression.

Tao R, Xiong X, DePinho RA, Deng CX, Dong XC.

J Biol Chem. 2013 Oct 11;288(41):29252-9. doi: 10.1074/jbc.M113.481473. Epub 2013 Aug 23.

PMID:
23974119
[PubMed - indexed for MEDLINE]

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