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Items: 1 to 20 of 95

1.

Diaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction.

Manders E, de Man FS, Handoko ML, Westerhof N, van Hees HW, Stienen GJ, Vonk-Noordegraaf A, Ottenheijm CA.

Am J Physiol Lung Cell Mol Physiol. 2012 Dec 15;303(12):L1070-8. doi: 10.1152/ajplung.00135.2012. Epub 2012 Sep 7.

2.

Diaphragm muscle fiber weakness in pulmonary hypertension.

de Man FS, van Hees HW, Handoko ML, Niessen HW, Schalij I, Humbert M, Dorfmüller P, Mercier O, Bogaard HJ, Postmus PE, Westerhof N, Stienen GJ, van der Laarse WJ, Vonk-Noordegraaf A, Ottenheijm CA.

Am J Respir Crit Care Med. 2011 May 15;183(10):1411-8. doi: 10.1164/rccm.201003-0354OC. Epub 2010 Dec 3.

PMID:
21131469
3.

Diaphragm single-fiber weakness and loss of myosin in congestive heart failure rats.

van Hees HW, van der Heijden HF, Ottenheijm CA, Heunks LM, Pigmans CJ, Verheugt FW, Brouwer RM, Dekhuijzen PN.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H819-28. Epub 2007 Apr 20.

4.

Levosimendan improves calcium sensitivity of diaphragm muscle fibres from a rat model of heart failure.

van Hees HW, Andrade Acuña G, Linkels M, Dekhuijzen PN, Heunks LM.

Br J Pharmacol. 2011 Feb;162(3):566-73. doi: 10.1111/j.1476-5381.2010.01048.x.

5.

Diaphragm dysfunction in chronic obstructive pulmonary disease.

Ottenheijm CA, Heunks LM, Sieck GC, Zhan WZ, Jansen SM, Degens H, de Boo T, Dekhuijzen PN.

Am J Respir Crit Care Med. 2005 Jul 15;172(2):200-5. Epub 2005 Apr 22.

6.

Endotoxin administration alters the force vs. pCa relationship of skeletal muscle fibers.

Supinski G, Nethery D, Nosek TM, Callahan LA, Stofan D, DiMarco A.

Am J Physiol Regul Integr Comp Physiol. 2000 Apr;278(4):R891-6.

7.

Levosimendan enhances force generation of diaphragm muscle from patients with chronic obstructive pulmonary disease.

van Hees HW, Dekhuijzen PN, Heunks LM.

Am J Respir Crit Care Med. 2009 Jan 1;179(1):41-7. doi: 10.1164/rccm.200805-732OC. Epub 2008 Oct 31.

PMID:
18990676
8.

Heart failure decreases passive tension generation of rat diaphragm fibers.

van Hees HW, Ottenheijm CA, Granzier HL, Dekhuijzen PN, Heunks LM.

Int J Cardiol. 2010 Jun 11;141(3):275-83. doi: 10.1016/j.ijcard.2008.12.042. Epub 2009 Jan 15.

PMID:
19150150
9.

Effects of hypothyroidism on maximum specific force in rat diaphragm muscle fibers.

Geiger PC, Cody MJ, Han YS, Hunter LW, Zhan WZ, Sieck GC.

J Appl Physiol (1985). 2002 Apr;92(4):1506-14.

10.

Selective diaphragm muscle weakness after contractile inactivity during thoracic surgery.

Welvaart WN, Paul MA, Stienen GJ, van Hees HW, Loer SA, Bouwman R, Niessen H, de Man FS, Witt CC, Granzier H, Vonk-Noordegraaf A, Ottenheijm CA.

Ann Surg. 2011 Dec;254(6):1044-9. doi: 10.1097/SLA.0b013e318232e75b.

PMID:
21975323
11.

Depressed contractile performance and reduced fatigue resistance in single skinned fibers of soleus muscle after long-term disuse in rats.

Udaka J, Terui T, Ohtsuki I, Marumo K, Ishiwata S, Kurihara S, Fukuda N.

J Appl Physiol (1985). 2011 Oct;111(4):1080-7. doi: 10.1152/japplphysiol.00330.2011. Epub 2011 Jun 30.

12.

Diaphragm muscle fiber dysfunction in chronic obstructive pulmonary disease: toward a pathophysiological concept.

Ottenheijm CA, Heunks LM, Dekhuijzen PN.

Am J Respir Crit Care Med. 2007 Jun 15;175(12):1233-40. Epub 2007 Apr 5. Review.

PMID:
17413128
13.

Mechanisms underlying skeletal muscle weakness in human heart failure: alterations in single fiber myosin protein content and function.

Miller MS, Vanburen P, Lewinter MM, Lecker SH, Selby DE, Palmer BM, Maughan DW, Ades PA, Toth MJ.

Circ Heart Fail. 2009 Nov;2(6):700-6. doi: 10.1161/CIRCHEARTFAILURE.109.876433. Epub 2009 Sep 24.

14.

Titin and diaphragm dysfunction in mechanically ventilated rats.

van Hees HW, Schellekens WJ, Andrade Acuña GL, Linkels M, Hafmans T, Ottenheijm CA, Granzier HL, Scheffer GJ, van der Hoeven JG, Dekhuijzen PN, Heunks LM.

Intensive Care Med. 2012 Apr;38(4):702-9. doi: 10.1007/s00134-012-2504-5. Epub 2012 Feb 11.

15.

Diaphragm atrophy and contractile dysfunction in a murine model of pulmonary hypertension.

Ahn B, Empinado HM, Al-Rajhi M, Judge AR, Ferreira LF.

PLoS One. 2013 Apr 22;8(4):e62702. doi: 10.1371/journal.pone.0062702. Print 2013.

16.

Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers.

Geiger PC, Cody MJ, Macken RL, Sieck GC.

J Appl Physiol (1985). 2000 Aug;89(2):695-703.

17.

Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness.

Powers SK, Hudson MB, Nelson WB, Talbert EE, Min K, Szeto HH, Kavazis AN, Smuder AJ.

Crit Care Med. 2011 Jul;39(7):1749-59. doi: 10.1097/CCM.0b013e3182190b62.

PMID:
21460706
18.

Sarcomeric dysfunction contributes to muscle weakness in facioscapulohumeral muscular dystrophy.

Lassche S, Stienen GJ, Irving TC, van der Maarel SM, Voermans NC, Padberg GW, Granzier H, van Engelen BG, Ottenheijm CA.

Neurology. 2013 Feb 19;80(8):733-7. doi: 10.1212/WNL.0b013e318282513b. Epub 2013 Jan 30.

19.

Application of skinned single muscle fibres to determine myofilament function in ageing and disease.

Degens H, Larsson L.

J Musculoskelet Neuronal Interact. 2007 Jan-Mar;7(1):56-61.

20.

Hypothyroid-mediated changes in adult rat diaphragm muscle contractile properties and MHC isoform expression.

Gosselin LE, Zhan WZ, Sieck GC.

J Appl Physiol (1985). 1996 Jun;80(6):1934-9.

PMID:
8806897
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