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Results: 1 to 20 of 72

1.

Does a β2-adrenergic receptor-WNK4-Na-Cl co-transporter signal cascade exist in the in vivo kidney?

Uchida S, Chiga M, Sohara E, Rai T, Sasaki S.

Nat Med. 2012 Sep;18(9):1324-5; author reply 1325-7. doi: 10.1038/nm.2809. No abstract available.

PMID:
22961153
[PubMed - indexed for MEDLINE]
2.

Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension.

Mu S, Shimosawa T, Ogura S, Wang H, Uetake Y, Kawakami-Mori F, Marumo T, Yatomi Y, Geller DS, Tanaka H, Fujita T.

Nat Med. 2011 May;17(5):573-80. doi: 10.1038/nm.2337. Epub 2011 Apr 17. Erratum in: Nat Med. 2011 Aug;17(8):1020. Nat Med. 2012 Apr;18(4):630.

PMID:
21499270
[PubMed - indexed for MEDLINE]
3.

WNK kinases, renal ion transport and hypertension.

San-Cristobal P, de los Heros P, Ponce-Coria J, Moreno E, Gamba G.

Am J Nephrol. 2008;28(5):860-70. doi: 10.1159/000139639. Epub 2008 Jun 12. Review.

PMID:
18547946
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Immunolocalization of WNK4 in mouse kidney.

Ohno M, Uchida K, Ohashi T, Nitta K, Ohta A, Chiga M, Sasaki S, Uchida S.

Histochem Cell Biol. 2011 Jul;136(1):25-35. doi: 10.1007/s00418-011-0827-x. Epub 2011 Jun 10.

PMID:
21660484
[PubMed - indexed for MEDLINE]
5.

WNK kinases influence TRPV4 channel function and localization.

Fu Y, Subramanya A, Rozansky D, Cohen DM.

Am J Physiol Renal Physiol. 2006 Jun;290(6):F1305-14. Epub 2006 Jan 10.

PMID:
16403833
[PubMed - indexed for MEDLINE]
Free Article
6.

Regulation of the expression of the Na/Cl cotransporter by WNK4 and WNK1: evidence that accelerated dynamin-dependent endocytosis is not involved.

Golbang AP, Cope G, Hamad A, Murthy M, Liu CH, Cuthbert AW, O'shaughnessy KM.

Am J Physiol Renal Physiol. 2006 Dec;291(6):F1369-76. Epub 2006 Jun 20.

PMID:
16788137
[PubMed - indexed for MEDLINE]
Free Article
7.

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.

Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, Lifton RP.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):680-4. Epub 2003 Jan 6.

PMID:
12515852
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The role of Wnk4 in polygenic hypertension: a candidate gene analysis on rat chromosome 10.

Monti J, Zimdahl H, Schulz H, Plehm R, Ganten D, Hübner N.

Hypertension. 2003 Apr;41(4):938-42. Epub 2003 Mar 17.

PMID:
12642508
[PubMed - indexed for MEDLINE]
Free Article
9.
10.

G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer.

Violin JD, Ren XR, Lefkowitz RJ.

J Biol Chem. 2006 Jul 21;281(29):20577-88. Epub 2006 May 10.

PMID:
16687412
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

[Correlation analysis between WNK4 gene and essential hypertension].

Sun ZJ, Wang XN, Lu JY, Ding Q, Dong LY, Zhao YY.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003 Apr;25(2):145-8. Chinese.

PMID:
12905707
[PubMed - indexed for MEDLINE]
13.

Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis.

Lombardi MS, Kavelaars A, Schedlowski M, Bijlsma JW, Okihara KL, Van de Pol M, Ochsmann S, Pawlak C, Schmidt RE, Heijnen CJ.

FASEB J. 1999 Apr;13(6):715-25.

PMID:
10094932
[PubMed - indexed for MEDLINE]
Free Article
14.

beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.

Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ.

J Biol Chem. 2006 Jan 13;281(2):1261-73. Epub 2005 Nov 9.

PMID:
16280323
[PubMed - indexed for MEDLINE]
Free Article
15.

Cotransporters, WNKs and hypertension: an update.

Flatman PW.

Curr Opin Nephrol Hypertens. 2008 Mar;17(2):186-92. doi: 10.1097/MNH.0b013e3282f5244e. Review.

PMID:
18277153
[PubMed - indexed for MEDLINE]
16.

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.

Ring AM, Cheng SX, Leng Q, Kahle KT, Rinehart J, Lalioti MD, Volkman HM, Wilson FH, Hebert SC, Lifton RP.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4020-4. Epub 2007 Feb 26.

PMID:
17360470
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.

Vitari AC, Deak M, Morrice NA, Alessi DR.

Biochem J. 2005 Oct 1;391(Pt 1):17-24.

PMID:
16083423
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

WNK1 and WNK4 modulate CFTR activity.

Yang CL, Liu X, Paliege A, Zhu X, Bachmann S, Dawson DC, Ellison DH.

Biochem Biophys Res Commun. 2007 Feb 16;353(3):535-40. Epub 2006 Dec 15.

PMID:
17194447
[PubMed - indexed for MEDLINE]
19.

The platelet-derived growth factor receptor-beta phosphorylates and activates G protein-coupled receptor kinase-2. A mechanism for feedback inhibition.

Wu JH, Goswami R, Kim LK, Miller WE, Peppel K, Freedman NJ.

J Biol Chem. 2005 Sep 2;280(35):31027-35. Epub 2005 Jul 1.

PMID:
15994317
[PubMed - indexed for MEDLINE]
Free Article
20.

WNK lies upstream of kinases involved in regulation of ion transporters.

Gamba G.

Biochem J. 2005 Oct 1;391(Pt 1):e1-3.

PMID:
16173916
[PubMed - indexed for MEDLINE]
Free PMC Article

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