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Items: 1 to 20 of 129

1.

Mechanism for Hypocretin-mediated sleep-to-wake transitions.

Carter ME, Brill J, Bonnavion P, Huguenard JR, Huerta R, de Lecea L.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2635-44. Epub 2012 Sep 5.

2.

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

Bourgin P, Huitrón-Résendiz S, Spier AD, Fabre V, Morte B, Criado JR, Sutcliffe JG, Henriksen SJ, de Lecea L.

J Neurosci. 2000 Oct 15;20(20):7760-5.

3.

Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions.

Carter ME, Adamantidis A, Ohtsu H, Deisseroth K, de Lecea L.

J Neurosci. 2009 Sep 2;29(35):10939-49. doi: 10.1523/JNEUROSCI.1205-09.2009.

4.

Neural substrates of awakening probed with optogenetic control of hypocretin neurons.

Adamantidis AR, Zhang F, Aravanis AM, Deisseroth K, de Lecea L.

Nature. 2007 Nov 15;450(7168):420-4. Epub 2007 Oct 17.

PMID:
17943086
5.
6.

Chronic alterations in monoaminergic cells in the locus coeruleus in orexin neuron-ablated narcoleptic mice.

Tsujino N, Tsunematsu T, Uchigashima M, Konno K, Yamanaka A, Kobayashi K, Watanabe M, Koyama Y, Sakurai T.

PLoS One. 2013 Jul 29;8(7):e70012. doi: 10.1371/journal.pone.0070012. Print 2013.

7.

Control of cardiovascular variability during undisturbed wake-sleep behavior in hypocretin-deficient mice.

Silvani A, Bastianini S, Berteotti C, Lo Martire V, Zoccoli G.

Am J Physiol Regul Integr Comp Physiol. 2012 Apr 15;302(8):R958-64. doi: 10.1152/ajpregu.00668.2011. Epub 2012 Feb 22.

8.

Hypocretin-2 saporin lesions of the ventrolateral periaquaductal gray (vlPAG) increase REM sleep in hypocretin knockout mice.

Kaur S, Thankachan S, Begum S, Liu M, Blanco-Centurion C, Shiromani PJ.

PLoS One. 2009 Jul 22;4(7):e6346. doi: 10.1371/journal.pone.0006346.

9.

Projections from melanin-concentrating hormone (MCH) neurons to the dorsal raphe or the nuclear core of the locus coeruleus in the rat.

Yoon YS, Lee HS.

Brain Res. 2013 Jan 15;1490:72-82. doi: 10.1016/j.brainres.2012.08.022. Epub 2012 Sep 5.

PMID:
22967922
10.

Release of hypocretin (orexin) during waking and sleep states.

Kiyashchenko LI, Mileykovskiy BY, Maidment N, Lam HA, Wu MF, John J, Peever J, Siegel JM.

J Neurosci. 2002 Jul 1;22(13):5282-6.

11.

A1 receptor mediated adenosinergic regulation of perifornical-lateral hypothalamic area neurons in freely behaving rats.

Rai S, Kumar S, Alam MA, Szymusiak R, McGinty D, Alam MN.

Neuroscience. 2010 Apr 28;167(1):40-8. doi: 10.1016/j.neuroscience.2010.01.044. Epub 2010 Jan 28.

12.

Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep.

Schwartz MD, Nguyen AT, Warrier DR, Palmerston JB, Thomas AM, Morairty SR, Neylan TC, Kilduff TS.

eNeuro. 2016 Mar 21;3(2). pii: ENEURO.0018-16.2016. doi: 10.1523/ENEURO.0018-16.2016. eCollection 2016 Mar-Apr.

13.

Opposite effects of noradrenaline and acetylcholine upon hypocretin/orexin versus melanin concentrating hormone neurons in rat hypothalamic slices.

Bayer L, Eggermann E, Serafin M, Grivel J, Machard D, Muhlethaler M, Jones BE.

Neuroscience. 2005;130(4):807-11.

PMID:
15652980
14.

Distribution of hypocretin (orexin) immunoreactivity in the feline pons and medulla.

Zhang JH, Sampogna S, Morales FR, Chase MH.

Brain Res. 2004 Jan 9;995(2):205-17.

PMID:
14672810
15.

Effects of rapid eye movement sleep deprivation on hypocretin neurons in the hypothalamus of a rat model of depression.

Allard JS, Tizabi Y, Shaffery JP, Manaye K.

Neuropeptides. 2007 Oct;41(5):329-37. Epub 2007 Jun 27.

17.

Altered sleep homeostasis after restraint stress in 5-HTT knock-out male mice: a role for hypocretins.

Rachalski A, Alexandre C, Bernard JF, Saurini F, Lesch KP, Hamon M, Adrien J, Fabre V.

J Neurosci. 2009 Dec 9;29(49):15575-85. doi: 10.1523/JNEUROSCI.3138-09.2009.

18.

Genetic ablation of hypocretin neurons alters behavioral state transitions in zebrafish.

Elbaz I, Yelin-Bekerman L, Nicenboim J, Vatine G, Appelbaum L.

J Neurosci. 2012 Sep 12;32(37):12961-72. doi: 10.1523/JNEUROSCI.1284-12.2012.

19.

Effects of hypocretin (orexin) neuronal loss on sleep and extracellular adenosine levels in the rat basal forebrain.

Murillo-Rodriguez E, Liu M, Blanco-Centurion C, Shiromani PJ.

Eur J Neurosci. 2008 Sep;28(6):1191-8. doi: 10.1111/j.1460-9568.2008.06424.x. Epub 2008 Sep 9.

20.

The wake-promoting effects of hypocretin-1 are attenuated in old rats.

Morairty SR, Wisor J, Silveira K, Sinko W, Kilduff TS.

Neurobiol Aging. 2011 Aug;32(8):1514-27. doi: 10.1016/j.neurobiolaging.2009.07.017. Epub 2009 Sep 24.

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