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Results: 1 to 20 of 98

1.

Development of multi-route physiologically-based pharmacokinetic models for ethanol in the adult, pregnant, and neonatal rat.

Martin SA, McLanahan ED, El-Masri H, LeFew WR, Bushnell PJ, Boyes WK, Choi K, Clewell HJ 3rd, Campbell JL Jr.

Inhal Toxicol. 2012 Sep;24(11):698-722. doi: 10.3109/08958378.2012.712165.

PMID:
22954395
[PubMed - indexed for MEDLINE]
2.

Physiologically based pharmacokinetic modeling of the pregnant rat: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid.

Fisher JW, Whittaker TA, Taylor DH, Clewell HJ 3rd, Andersen ME.

Toxicol Appl Pharmacol. 1989 Jul;99(3):395-414.

PMID:
2749729
[PubMed - indexed for MEDLINE]
3.

A comparison of physiologically based pharmacokinetic model predictions and experimental data for inhaled ethanol in male and female B6C3F1 mice, F344 rats, and humans.

Pastino GM, Asgharian B, Roberts K, Medinsky MA, Bond JA.

Toxicol Appl Pharmacol. 1997 Jul;145(1):147-57.

PMID:
9221833
[PubMed - indexed for MEDLINE]
4.

Analysis of manganese tracer kinetics and target tissue dosimetry in monkeys and humans with multi-route physiologically based pharmacokinetic models.

Schroeter JD, Nong A, Yoon M, Taylor MD, Dorman DC, Andersen ME, Clewell HJ 3rd.

Toxicol Sci. 2011 Apr;120(2):481-98. doi: 10.1093/toxsci/kfq389. Epub 2010 Dec 27.

PMID:
21205636
[PubMed - indexed for MEDLINE]
Free Article
5.

Physiologically based pharmacokinetic modeling of fetal and neonatal manganese exposure in humans: describing manganese homeostasis during development.

Yoon M, Schroeter JD, Nong A, Taylor MD, Dorman DC, Andersen ME, Clewell HJ 3rd.

Toxicol Sci. 2011 Aug;122(2):297-316. doi: 10.1093/toxsci/kfr141. Epub 2011 May 27.

PMID:
21622944
[PubMed - indexed for MEDLINE]
Free Article
6.

Physiologically-based pharmacokinetic model for Fentanyl in support of the development of Provisional Advisory Levels.

Shankaran H, Adeshina F, Teeguarden JG.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):464-76. doi: 10.1016/j.taap.2013.05.024. Epub 2013 May 31.

PMID:
23732079
[PubMed - indexed for MEDLINE]
7.

PBPK models in risk assessment--A focus on chloroprene.

DeWoskin RS.

Chem Biol Interact. 2007 Mar 20;166(1-3):352-9. Epub 2007 Feb 8.

PMID:
17324392
[PubMed - indexed for MEDLINE]
8.

Evaluating placental transfer and tissue concentrations of manganese in the pregnant rat and fetuses after inhalation exposures with a PBPK model.

Yoon M, Nong A, Clewell HJ 3rd, Taylor MD, Dorman DC, Andersen ME.

Toxicol Sci. 2009 Nov;112(1):44-58. doi: 10.1093/toxsci/kfp198. Epub 2009 Sep 2.

PMID:
19726578
[PubMed - indexed for MEDLINE]
Free Article
9.

Route-specific differences in distribution characteristics of octamethylcyclotetrasiloxane in rats: analysis using PBPK models.

Sarangapani R, Teeguarden J, Andersen ME, Reitz RH, Plotzke KP.

Toxicol Sci. 2003 Jan;71(1):41-52.

PMID:
12520074
[PubMed - indexed for MEDLINE]
Free Article
10.

Physiologically based pharmacokinetic modeling of cyclotrimethylenetrinitramine in male rats.

Krishnan K, Crouse LC, Bazar MA, Major MA, Reddy G.

J Appl Toxicol. 2009 Oct;29(7):629-37. doi: 10.1002/jat.1455.

PMID:
19629953
[PubMed - indexed for MEDLINE]
11.

Development of a physiologically based model for oseltamivir and simulation of pharmacokinetics in neonates and infants.

Parrott N, Davies B, Hoffmann G, Koerner A, Lave T, Prinssen E, Theogaraj E, Singer T.

Clin Pharmacokinet. 2011 Sep;50(9):613-23. doi: 10.2165/11592640-000000000-00000.

PMID:
21827216
[PubMed - indexed for MEDLINE]
12.

Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone.

Clewell HJ 3rd, Gentry PR, Gearhart JM, Covington TR, Banton MI, Andersen ME.

Toxicol Sci. 2001 Oct;63(2):160-72.

PMID:
11568359
[PubMed - indexed for MEDLINE]
Free Article
13.

A physiologically based pharmacokinetic (PB/PK) model for multiple exposure routes of soman in multiple species.

Sweeney RE, Langenberg JP, Maxwell DM.

Arch Toxicol. 2006 Nov;80(11):719-31. Epub 2006 May 23.

PMID:
16718492
[PubMed - indexed for MEDLINE]
14.

Evaluation of placental and lactational pharmacokinetics of PFOA and PFOS in the pregnant, lactating, fetal and neonatal rat using a physiologically based pharmacokinetic model.

Loccisano AE, Campbell JL Jr, Butenhoff JL, Andersen ME, Clewell HJ 3rd.

Reprod Toxicol. 2012 Jul;33(4):468-90. doi: 10.1016/j.reprotox.2011.07.003. Epub 2011 Aug 18.

PMID:
21872655
[PubMed - indexed for MEDLINE]
15.

Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake.

Laplanche R, Meno-Tetang GM, Kawai R.

J Pharmacokinet Pharmacodyn. 2007 Jun;34(3):373-400. Epub 2007 Mar 13.

PMID:
17431753
[PubMed - indexed for MEDLINE]
16.

Maternal-fetal pharmacokinetics of methanol.

Pollack GM, Brouwer KL.

Res Rep Health Eff Inst. 1996 Jun;(74):1-48; discussion 49-53.

PMID:
11381741
[PubMed - indexed for MEDLINE]
17.

Manganese tissue dosimetry in rats and monkeys: accounting for dietary and inhaled Mn with physiologically based pharmacokinetic modeling.

Nong A, Taylor MD, Clewell HJ 3rd, Dorman DC, Andersen ME.

Toxicol Sci. 2009 Mar;108(1):22-34. doi: 10.1093/toxsci/kfn264. Epub 2008 Dec 19.

PMID:
19098275
[PubMed - indexed for MEDLINE]
Free Article
18.
19.

Development of a physiologically based pharmacokinetic model for bisphenol A in pregnant mice.

Kawamoto Y, Matsuyama W, Wada M, Hishikawa J, Chan MP, Nakayama A, Morisawa S.

Toxicol Appl Pharmacol. 2007 Oct 15;224(2):182-91. Epub 2007 Jul 12.

PMID:
17698157
[PubMed - indexed for MEDLINE]
20.

Tissue dosimetry expansion and cross-validation of rat and mouse physiologically based pharmacokinetic models for trichloroethylene.

Keys DA, Bruckner JV, Muralidhara S, Fisher JW.

Toxicol Sci. 2003 Nov;76(1):35-50. Epub 2003 Aug 12.

PMID:
12915716
[PubMed - indexed for MEDLINE]
Free Article

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