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Items: 1 to 20 of 131

1.

Molecular mechanism of pancreatic tumor metastasis inhibition by Gd@C82(OH)22 and its implication for de novo design of nanomedicine.

Kang SG, Zhou G, Yang P, Liu Y, Sun B, Huynh T, Meng H, Zhao L, Xing G, Chen C, Zhao Y, Zhou R.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15431-6. Epub 2012 Sep 4.

2.

Dual inhibitory pathways of metallofullerenol Gd@C₈₂(OH)₂₂ on matrix metalloproteinase-2: molecular insight into drug-like nanomedicine.

Kang SG, Araya-Secchi R, Wang D, Wang B, Huynh T, Zhou R.

Sci Rep. 2014 Apr 24;4:4775. doi: 10.1038/srep04775.

3.

Inhibition of tumor growth by endohedral metallofullerenol nanoparticles optimized as reactive oxygen species scavenger.

Yin JJ, Lao F, Meng J, Fu PP, Zhao Y, Xing G, Gao X, Sun B, Wang PC, Chen C, Liang XJ.

Mol Pharmacol. 2008 Oct;74(4):1132-40. doi: 10.1124/mol.108.048348. Epub 2008 Jul 17.

4.

Metallofullerenol Gd@C₈₂(OH)₂₂ distracts the proline-rich-motif from putative binding on the SH3 domain.

Kang SG, Huynh T, Zhou R.

Nanoscale. 2013 Apr 7;5(7):2703-12. doi: 10.1039/c3nr33756a.

PMID:
23423582
5.

Non-destructive inhibition of metallofullerenol Gd@C(82)(OH)(22) on WW domain: implication on signal transduction pathway.

Kang SG, Huynh T, Zhou R.

Sci Rep. 2012;2:957. doi: 10.1038/srep00957. Epub 2012 Dec 11.

6.

Biomedical activities of endohedral metallofullerene optimized for nanopharmaceutics.

Meng J, Wang DL, Wang PC, Jia L, Chen C, Liang XJ.

J Nanosci Nanotechnol. 2010 Dec;10(12):8610-6.

7.

Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor.

Liu Y, Chen C, Qian P, Lu X, Sun B, Zhang X, Wang L, Gao X, Li H, Chen Z, Tang J, Zhang W, Dong J, Bai R, Lobie PE, Wu Q, Liu S, Zhang H, Zhao F, Wicha MS, Zhu T, Zhao Y.

Nat Commun. 2015 Jan 23;6:5988. doi: 10.1038/ncomms6988.

8.

Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer.

Fujisawa T, Rubin B, Suzuki A, Patel PS, Gahl WA, Joshi BH, Puri RK.

PLoS One. 2012;7(4):e34437. doi: 10.1371/journal.pone.0034437. Epub 2012 Apr 20.

9.

Gd-Metallofullerenol Nanomaterial Suppresses Pancreatic Cancer Metastasis by Inhibiting the Interaction of Histone Deacetylase 1 and Metastasis-Associated Protein 1.

Pan Y, Wang L, Kang SG, Lu Y, Yang Z, Huynh T, Chen C, Zhou R, Guo M, Zhao Y.

ACS Nano. 2015 Jul 28;9(7):6826-36. doi: 10.1021/nn506782f. Epub 2015 Jun 22.

PMID:
26083726
10.

Antioxidative function and biodistribution of [Gd@C82(OH)22]n nanoparticles in tumor-bearing mice.

Wang J, Chen C, Li B, Yu H, Zhao Y, Sun J, Li Y, Xing G, Yuan H, Tang J, Chen Z, Meng H, Gao Y, Ye C, Chai Z, Zhu C, Ma B, Fang X, Wan L.

Biochem Pharmacol. 2006 Mar 14;71(6):872-81. Epub 2006 Jan 24.

PMID:
16436273
11.

Large scale molecular simulations of nanotoxicity.

Jimenez-Cruz CA, Kang SG, Zhou R.

Wiley Interdiscip Rev Syst Biol Med. 2014 Jul-Aug;6(4):329-43. doi: 10.1002/wsbm.1271. Epub 2014 Jun 4. Review.

PMID:
24894909
12.

Impacts of fullerene derivatives on regulating the structure and assembly of collagen molecules.

Yin X, Zhao L, Kang SG, Pan J, Song Y, Zhang M, Xing G, Wang F, Li J, Zhou R, Zhao Y.

Nanoscale. 2013 Aug 21;5(16):7341-8. doi: 10.1039/c3nr01469j.

PMID:
23820497
13.

Organ heterogeneity of host-derived matrix metalloproteinase expression and its involvement in multiple-organ metastasis by lung cancer cell lines.

Shiraga M, Yano S, Yamamoto A, Ogawa H, Goto H, Miki T, Miki K, Zhang H, Sone S.

Cancer Res. 2002 Oct 15;62(20):5967-73.

14.

Transmembrane delivery of aggregated [Gd@C82(OH)22]n nanoparticles.

Zhang M, Xing G, Yuan H, Chang X, Jing L, Zhao Y, Zhu C, Fang X.

J Nanosci Nanotechnol. 2010 Dec;10(12):8556-61.

PMID:
21121366
16.
17.

Matrix metalloproteinase inhibitors.

Wojtowicz-Praga SM, Dickson RB, Hawkins MJ.

Invest New Drugs. 1997;15(1):61-75. Review.

PMID:
9195290
18.

Matrix metalloproteinase inhibitors: a review on pharmacophore mapping and (Q)SARs results.

Kontogiorgis CA, Papaioannou P, Hadjipavlou-Litina DJ.

Curr Med Chem. 2005;12(3):339-55. Review.

PMID:
15723623
19.

Induction of apoptosis through ER stress and TP53 in MCF-7 cells by the nanoparticle [Gd@C82(OH)22]n: A systems biology study.

Wang L, Meng J, Cao W, Li Q, Qiu Y, Sun B, Li LM.

Methods. 2014 Jun 1;67(3):394-406. doi: 10.1016/j.ymeth.2014.01.007. Epub 2014 Jan 15.

PMID:
24440483
20.

Characterisation of a novel matrix metalloproteinase inhibitor on pancreatic adenocarcinoma cells in vitro and in an orthotopic pancreatic cancer model in vivo.

Kapischke M, Fischer T, Tiessen K, Tschesche H, Bruch HP, Kalthoff H, Kruse ML.

Int J Oncol. 2008 Jan;32(1):273-82.

PMID:
18097568
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