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Items: 1 to 20 of 155

1.

Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation.

Banerjee N, Talcott S, Safe S, Mertens-Talcott SU.

Breast Cancer Res Treat. 2012 Nov;136(1):21-34. doi: 10.1007/s10549-012-2224-0. Epub 2012 Sep 2.

2.

Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: role of Sp transcription factors and microRNA-27a:ZBTB10.

Mertens-Talcott SU, Noratto GD, Li X, Angel-Morales G, Bertoldi MC, Safe S.

Mol Carcinog. 2013 Aug;52(8):591-602. doi: 10.1002/mc.21893. Epub 2012 Mar 7.

3.
4.

Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs.

Banerjee N, Kim H, Krenek K, Talcott ST, Mertens-Talcott SU.

Nutr Res. 2015 Aug;35(8):744-51. doi: 10.1016/j.nutres.2015.06.002. Epub 2015 Jun 11.

PMID:
26194618
5.
6.

Curcumin and synthetic analogs induce reactive oxygen species and decreases specificity protein (Sp) transcription factors by targeting microRNAs.

Gandhy SU, Kim K, Larsen L, Rosengren RJ, Safe S.

BMC Cancer. 2012 Nov 30;12:564. doi: 10.1186/1471-2407-12-564.

7.

GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway.

Pathi SS, Jutooru I, Chadalapaka G, Sreevalsan S, Anand S, Thatcher GR, Safe S.

Mol Cancer Res. 2011 Feb;9(2):195-202. doi: 10.1158/1541-7786.MCR-10-0363. Epub 2010 Dec 14.

8.

Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR.

Banerjee N, Kim H, Talcott S, Mertens-Talcott S.

Carcinogenesis. 2013 Dec;34(12):2814-22. doi: 10.1093/carcin/bgt295. Epub 2013 Aug 29.

9.

MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells.

Li X, Mertens-Talcott SU, Zhang S, Kim K, Ball J, Safe S.

Endocrinology. 2010 Jun;151(6):2462-73. doi: 10.1210/en.2009-1150. Epub 2010 Apr 9.

10.

Betulinic acid targets YY1 and ErbB2 through cannabinoid receptor-dependent disruption of microRNA-27a:ZBTB10 in breast cancer.

Liu X, Jutooru I, Lei P, Kim K, Lee SO, Brents LK, Prather PL, Safe S.

Mol Cancer Ther. 2012 Jul;11(7):1421-31. doi: 10.1158/1535-7163.MCT-12-0026. Epub 2012 May 2.

11.

The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis.

Noratto GD, Jutooru I, Safe S, Angel-Morales G, Mertens-Talcott SU.

Mol Nutr Food Res. 2013 Sep;57(9):1638-48. doi: 10.1002/mnfr.201200609. Epub 2013 Mar 8.

PMID:
23471840
12.

Anti-proliferative effects of polyphenols from pomegranate rind (Punica granatum L.) on EJ bladder cancer cells via regulation of p53/miR-34a axis.

Zhou B, Yi H, Tan J, Wu Y, Liu G, Qiu Z.

Phytother Res. 2015 Mar;29(3):415-22. doi: 10.1002/ptr.5267. Epub 2015 Jan 8.

PMID:
25572695
13.

Combination of quercetin and hyperoside has anticancer effects on renal cancer cells through inhibition of oncogenic microRNA-27a.

Li W, Liu M, Xu YF, Feng Y, Che JP, Wang GC, Zheng JH.

Oncol Rep. 2014 Jan;31(1):117-24. doi: 10.3892/or.2013.2811. Epub 2013 Oct 24.

PMID:
24173369
14.

AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells.

Rabi T, Huwiler A, Zangemeister-Wittke U.

Mol Carcinog. 2014 Jul;53(7):578-88. doi: 10.1002/mc.22012. Epub 2013 Mar 8.

PMID:
23475563
15.

The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells.

Sreevalsan S, Safe S.

Mol Cancer Ther. 2013 Nov;12(11):2483-93. doi: 10.1158/1535-7163.MCT-13-0486. Epub 2013 Sep 12.

16.

Potential anti-inflammatory effects of the hydrophilic fraction of pomegranate (Punica granatum L.) seed oil on breast cancer cell lines.

Costantini S, Rusolo F, De Vito V, Moccia S, Picariello G, Capone F, Guerriero E, Castello G, Volpe MG.

Molecules. 2014 Jun 24;19(6):8644-60. doi: 10.3390/molecules19068644.

17.

Antiproliferative effects of pomegranate extract in MCF-7 breast cancer cells are associated with reduced DNA repair gene expression and induction of double strand breaks.

Shirode AB, Kovvuru P, Chittur SV, Henning SM, Heber D, Reliene R.

Mol Carcinog. 2014 Jun;53(6):458-70. doi: 10.1002/mc.21995. Epub 2013 Jan 28.

PMID:
23359482
18.

Pomegranate fruit extract impairs invasion and motility in human breast cancer.

Khan GN, Gorin MA, Rosenthal D, Pan Q, Bao LW, Wu ZF, Newman RA, Pawlus AD, Yang P, Lansky EP, Merajver SD.

Integr Cancer Ther. 2009 Sep;8(3):242-53. doi: 10.1177/1534735409341405.

PMID:
19815594
19.

Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells.

Chintharlapalli S, Papineni S, Abdelrahim M, Abudayyeh A, Jutooru I, Chadalapaka G, Wu F, Mertens-Talcott S, Vanderlaag K, Cho SD, Smith R 3rd, Safe S.

Int J Cancer. 2009 Oct 15;125(8):1965-74. doi: 10.1002/ijc.24530.

20.

Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation.

Jutooru I, Chadalapaka G, Lei P, Safe S.

J Biol Chem. 2010 Aug 13;285(33):25332-44. doi: 10.1074/jbc.M109.095240. Epub 2010 Jun 9.

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