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Items: 1 to 20 of 161

1.

Relaxin-expressing adenovirus decreases collagen synthesis and up-regulates matrix metalloproteinase expression in keloid fibroblasts: in vitro experiments.

Lee WJ, Choi IK, Lee JH, Lee JS, Kim YO, Rah DK, Yun CO.

Plast Reconstr Surg. 2012 Sep;130(3):407e-17e. doi: 10.1097/PRS.0b013e31825dbf56.

PMID:
22929264
2.

Adenovirus-relaxin gene therapy for keloids: implication for reversing pathological fibrosis.

Lee WJ, Kim YO, Choi IK, Rah DK, Yun CO.

Br J Dermatol. 2011 Sep;165(3):673-7. doi: 10.1111/j.1365-2133.2011.10439.x.

PMID:
21623756
3.

Decorin-expressing adenovirus decreases collagen synthesis and upregulates MMP expression in keloid fibroblasts and keloid spheroids.

Lee WJ, Ahn HM, Roh H, Na Y, Choi IK, Lee JH, Kim YO, Lew DH, Yun CO.

Exp Dermatol. 2015 Aug;24(8):591-7. doi: 10.1111/exd.12719. Epub 2015 May 8.

PMID:
25865370
4.

Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model.

Lee WJ, Lee JH, Ahn HM, Song SY, Kim YO, Lew DH, Yun CO.

Plast Reconstr Surg. 2015 Sep;136(3):328e-337e. doi: 10.1097/PRS.0000000000001538.

PMID:
26313837
5.

Hepatocyte growth factor-expressing adenovirus upregulates matrix metalloproteinase-1 expression in keloid fibroblasts.

Jeon YR, Ahn HM, Choi IK, Yun CO, Rah DK, Lew DH, Lee WJ.

Int J Dermatol. 2016 Mar;55(3):356-61. doi: 10.1111/ijd.12965. Epub 2015 Jul 31.

PMID:
26234705
6.

The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.

Heeg MH, Koziolek MJ, Vasko R, Schaefer L, Sharma K, Müller GA, Strutz F.

Kidney Int. 2005 Jul;68(1):96-109.

7.

Compound Astragalus and Salvia miltiorrhiza extract inhibits cell proliferation, invasion and collagen synthesis in keloid fibroblasts by mediating transforming growth factor-β / Smad pathway.

He S, Yang Y, Liu X, Huang W, Zhang X, Yang S, Zhang X.

Br J Dermatol. 2012 Mar;166(3):564-74. doi: 10.1111/j.1365-2133.2011.10674.x. Epub 2011 Dec 5.

PMID:
21967214
8.

Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts.

Wang Z, Gao Z, Shi Y, Sun Y, Lin Z, Jiang H, Hou T, Wang Q, Yuan X, Zhu X, Wu H, Jin Y.

J Plast Reconstr Aesthet Surg. 2007;60(11):1193-9. Epub 2007 Jan 19.

PMID:
17889631
9.
10.

Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts.

Mun JH, Kim YM, Kim BS, Kim JH, Kim MB, Ko HC.

Wound Repair Regen. 2014 Jan-Feb;22(1):125-33. doi: 10.1111/wrr.12136. Epub 2013 Dec 13.

PMID:
24471776
11.

Effects of hepatocyte growth factor on collagen synthesis and matrix metalloproteinase production in keloids.

Lee WJ, Park SE, Rah DK.

J Korean Med Sci. 2011 Aug;26(8):1081-6. doi: 10.3346/jkms.2011.26.8.1081. Epub 2011 Jul 27.

13.

Tretinoin reverses upregulation of matrix metalloproteinase-13 in human keloid-derived fibroblasts.

Uchida G, Yoshimura K, Kitano Y, Okazaki M, Harii K.

Exp Dermatol. 2003;12 Suppl 2:35-42.

PMID:
14756522
14.

Oxymatrine inhibits collagen synthesis in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway.

Fan DL, Zhao WJ, Wang YX, Han SY, Guo S.

Int J Dermatol. 2012 Apr;51(4):463-72. doi: 10.1111/j.1365-4632.2011.05234.x.

PMID:
22435440
15.

FK506 inhibits the enhancing effects of transforming growth factor (TGF)-β1 on collagen expression and TGF-β/Smad signalling in keloid fibroblasts: implication for new therapeutic approach.

Wu CS, Wu PH, Fang AH, Lan CC.

Br J Dermatol. 2012 Sep;167(3):532-41. doi: 10.1111/j.1365-2133.2012.11023.x. Epub 2012 Jul 19.

PMID:
22540338
16.

Differential expression of transforming growth factor-beta receptors I and II and activation of Smad 3 in keloid fibroblasts.

Chin GS, Liu W, Peled Z, Lee TY, Steinbrech DS, Hsu M, Longaker MT.

Plast Reconstr Surg. 2001 Aug;108(2):423-9.

PMID:
11496185
17.

Modulation of collagen synthesis in keloid fibroblasts by silencing Smad2 with siRNA.

Gao Z, Wang Z, Shi Y, Lin Z, Jiang H, Hou T, Wang Q, Yuan X, Zhao Y, Wu H, Jin Y.

Plast Reconstr Surg. 2006 Nov;118(6):1328-37.

PMID:
17051103
18.

Relaxin prevents cardiac fibroblast-myofibroblast transition via notch-1-mediated inhibition of TGF-β/Smad3 signaling.

Sassoli C, Chellini F, Pini A, Tani A, Nistri S, Nosi D, Zecchi-Orlandini S, Bani D, Formigli L.

PLoS One. 2013 May 21;8(5):e63896. doi: 10.1371/journal.pone.0063896. Print 2013.

19.

Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts.

Zhang GY, Yi CG, Li X, Ma B, Li ZJ, Chen XL, Guo SZ, Gao WY.

Br J Dermatol. 2009 Apr;160(4):762-70. doi: 10.1111/j.1365-2133.2008.08989.x. Epub 2008 Dec 2.

PMID:
19120328
20.

Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts.

Tang B, Zhu B, Liang Y, Bi L, Hu Z, Chen B, Zhang K, Zhu J.

Arch Dermatol Res. 2011 Oct;303(8):563-72. doi: 10.1007/s00403-010-1114-8. Epub 2011 Jan 15.

PMID:
21240513
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