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Items: 1 to 20 of 109

1.

Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.

van der Goot AT, Zhu W, Vázquez-Manrique RP, Seinstra RI, Dettmer K, Michels H, Farina F, Krijnen J, Melki R, Buijsman RC, Ruiz Silva M, Thijssen KL, Kema IP, Neri C, Oefner PJ, Nollen EA.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14912-7. doi: 10.1073/pnas.1203083109. Epub 2012 Aug 27.

2.

Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain.

Wu W, Nicolazzo JA, Wen L, Chung R, Stankovic R, Bao SS, Lim CK, Brew BJ, Cullen KM, Guillemin GJ.

PLoS One. 2013 Apr 22;8(4):e59749. doi: 10.1371/journal.pone.0059749. Print 2013.

3.

Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.

Ott M, Litzenburger UM, Rauschenbach KJ, Bunse L, Ochs K, Sahm F, Pusch S, Opitz CA, Blaes J, von Deimling A, Wick W, Platten M.

Glia. 2015 Jan;63(1):78-90. doi: 10.1002/glia.22734. Epub 2014 Aug 5.

PMID:
25132599
4.

Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.

van Ham TJ, Holmberg MA, van der Goot AT, Teuling E, Garcia-Arencibia M, Kim HE, Du D, Thijssen KL, Wiersma M, Burggraaff R, van Bergeijk P, van Rheenen J, Jerre van Veluw G, Hofstra RM, Rubinsztein DC, Nollen EA.

Cell. 2010 Aug 20;142(4):601-12. doi: 10.1016/j.cell.2010.07.020.

5.

Skin L-tryptophan-2,3-dioxygenase and rat hair growth.

Ishiguro I, Naito J, Saito K, Nagamura Y.

FEBS Lett. 1993 Aug 23;329(1-2):178-82.

6.

Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats.

Braidy N, Guillemin GJ, Mansour H, Chan-Ling T, Grant R.

FEBS J. 2011 Nov;278(22):4425-34. doi: 10.1111/j.1742-4658.2011.08366.x.

7.

Extension of life span of Drosophila melanogaster by the inhibitors of tryptophan-kynurenine metabolism.

Oxenkrug GF, Navrotskaya V, Voroboyva L, Summergrad P.

Fly (Austin). 2011 Oct-Dec;5(4):307-9. doi: 10.4161/fly.5.4.18414. Epub 2011 Oct 1.

8.

Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.

Gibney SM, Fagan EM, Waldron AM, O'Byrne J, Connor TJ, Harkin A.

Int J Neuropsychopharmacol. 2014 Jun;17(6):917-28. doi: 10.1017/S1461145713001673. Epub 2014 Jan 29.

PMID:
24472498
9.

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.

Pilotte L, Larrieu P, Stroobant V, Colau D, Dolusic E, Frédérick R, De Plaen E, Uyttenhove C, Wouters J, Masereel B, Van den Eynde BJ.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2497-502. doi: 10.1073/pnas.1113873109. Epub 2012 Jan 30.

10.

Purification and biochemical characterization of a recombinant Anopheles gambiae tryptophan 2,3-dioxygenase expressed in Escherichia coli.

Paglino A, Lombardo F, Arcà B, Rizzi M, Rossi F.

Insect Biochem Mol Biol. 2008 Sep;38(9):871-6. doi: 10.1016/j.ibmb.2008.05.011. Epub 2008 Jul 17.

PMID:
18687401
11.

Heme: a regulator of rat hepatic tryptophan 2,3-dioxygenase?

Ren S, Correia MA.

Arch Biochem Biophys. 2000 May 1;377(1):195-203.

PMID:
10775460
12.

Efficient tryptophan-catabolizing activity is consistently conserved through evolution of TDO enzymes, but not IDO enzymes.

Yuasa HJ, Ball HJ.

J Exp Zool B Mol Dev Evol. 2015 Mar;324(2):128-40. doi: 10.1002/jez.b.22608. Epub 2015 Feb 20.

PMID:
25702628
13.

Identification and characterization of novel variants of the tryptophan 2,3-dioxygenase gene: differential regulation in the mouse nervous system during development.

Kanai M, Nakamura T, Funakoshi H.

Neurosci Res. 2009 May;64(1):111-7. doi: 10.1016/j.neures.2009.02.004. Epub 2009 Feb 20.

PMID:
19428689
14.

Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase.

Schmidt SK, Müller A, Heseler K, Woite C, Spekker K, MacKenzie CR, Däubener W.

Eur J Immunol. 2009 Oct;39(10):2755-64. doi: 10.1002/eji.200939535.

15.

Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation.

Li JS, Han Q, Fang J, Rizzi M, James AA, Li J.

Arch Insect Biochem Physiol. 2007 Feb;64(2):74-87.

16.

Oxidation of L-tryptophan in biology: a comparison between tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase.

Rafice SA, Chauhan N, Efimov I, Basran J, Raven EL.

Biochem Soc Trans. 2009 Apr;37(Pt 2):408-12. doi: 10.1042/BST0370408. Review.

PMID:
19290871
17.

Tryptophan pyrrole ring cleavage enzymes in placenta.

Minatogawa Y, Suzuki S, Ando Y, Tone S, Takikawa O.

Adv Exp Med Biol. 2003;527:425-34.

PMID:
15206760
18.

Quantitative and spatial differences in the expression of tryptophan-metabolizing enzymes in mouse epididymis.

Britan A, Maffre V, Tone S, Drevet JR.

Cell Tissue Res. 2006 May;324(2):301-10. Epub 2006 Feb 2.

PMID:
16450123
19.

Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases.

Muñoz-Lobato F, Rodríguez-Palero MJ, Naranjo-Galindo FJ, Shephard F, Gaffney CJ, Szewczyk NJ, Hamamichi S, Caldwell KA, Caldwell GA, Link CD, Miranda-Vizuete A.

Antioxid Redox Signal. 2014 Jan 10;20(2):217-35. doi: 10.1089/ars.2012.5051. Epub 2013 Jul 3.

20.

Expression of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase in early concepti.

Suzuki S, Toné S, Takikawa O, Kubo T, Kohno I, Minatogawa Y.

Biochem J. 2001 Apr 15;355(Pt 2):425-9.

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