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Items: 1 to 20 of 124

1.

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the tyrosine kinase inhibitor pazopanib in human plasma.

Sparidans RW, Ahmed TT, Muilwijk EW, Welzen ME, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;905:137-40. doi: 10.1016/j.jchromb.2012.08.004. Epub 2012 Aug 10.

PMID:
22917595
2.

Liquid chromatography-tandem mass spectrometric assay for the JAK2 inhibitor CYT387 in plasma.

Sparidans RW, Durmus S, Xu N, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 May 1;895-896:174-7. doi: 10.1016/j.jchromb.2012.03.021. Epub 2012 Mar 23.

PMID:
22476054
3.

Liquid chromatography-tandem mass spectrometric assay for the mutated BRAF inhibitor vemurafenib in human and mouse plasma.

Sparidans RW, Durmus S, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Mar 15;889-890:144-7. doi: 10.1016/j.jchromb.2012.02.010. Epub 2012 Feb 15.

PMID:
22386128
4.

Liquid chromatography-tandem mass spectrometric assay for the light sensitive tyrosine kinase inhibitor axitinib in human plasma.

Sparidans RW, Iusuf D, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Dec 15;877(32):4090-6. doi: 10.1016/j.jchromb.2009.10.024. Epub 2009 Oct 30.

PMID:
19910267
5.

Liquid chromatography-tandem mass spectrometry assay for therapeutic drug monitoring of the tyrosine kinase inhibitor, midostaurin, in plasma from patients with advanced systemic mastocytosis.

Bourget P, Amin A, Chandesris MO, Vidal F, Merlette C, Hirsch I, Cabaret L, Carvalhosa A, Mogenet A, Frenzel L, Damaj G, Lortholary O, Hermine O.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jan 1;944:175-81. doi: 10.1016/j.jchromb.2013.11.003. Epub 2013 Nov 15.

PMID:
24316764
6.

Liquid chromatography-tandem mass spectrometric assay for the ALK inhibitor crizotinib in mouse plasma.

Sparidans RW, Tang SC, Nguyen LN, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;905:150-4. doi: 10.1016/j.jchromb.2012.08.021. Epub 2012 Aug 21.

PMID:
22940474
7.

Liquid chromatography-tandem mass spectrometric assay for the PARP-1 inhibitor olaparib in combination with the nitrogen mustard melphalan in human plasma.

Sparidans RW, Martens I, Valkenburg-van Iersel LB, den Hartigh J, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 1;879(21):1851-6. doi: 10.1016/j.jchromb.2011.05.003. Epub 2011 May 7.

PMID:
21622034
8.

Liquid chromatography-tandem mass spectrometric assay for the VEGFR inhibitor cediranib and its primary human metabolite cediranib-N⁺-glucuronide in plasma.

Sparidans RW, Durmus S, Xu N, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 May 1;895-896:169-73. doi: 10.1016/j.jchromb.2012.03.020. Epub 2012 Mar 23.

PMID:
22476055
9.

Liquid chromatography-tandem mass spectrometric assay for pravastatin and two isomeric metabolites in mouse plasma and tissue homogenates.

Sparidans RW, Iusuf D, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Oct 15;878(28):2751-9. doi: 10.1016/j.jchromb.2010.08.015. Epub 2010 Aug 21.

PMID:
20829130
10.

Liquid chromatography-tandem mass spectrometric assay for the PI3K/mTOR inhibitor GSK2126458 in mouse plasma and tumor homogenate.

Dolman ME, Westerhout EM, Hamdi M, Schellens JH, Beijnen JH, Sparidans RW.

J Pharm Biomed Anal. 2015 Mar 25;107:403-8. doi: 10.1016/j.jpba.2015.01.026. Epub 2015 Jan 19.

PMID:
25659532
11.

Determination of pazopanib (GW-786034) in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry (LC/MS-MS).

Minocha M, Khurana V, Mitra AK.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jul 15;901:85-92. doi: 10.1016/j.jchromb.2012.06.004. Epub 2012 Jun 15.

12.

Liquid chromatography-tandem mass spectrometric assay for the multikinase inhibitor regorafenib in plasma.

Luethi D, Durmus S, Schinkel AH, Schellens JH, Beijnen JH, Sparidans RW.

Biomed Chromatogr. 2014 Oct;28(10):1366-70. doi: 10.1002/bmc.3176. Epub 2014 Mar 12.

PMID:
24619951
13.

Liquid chromatography-tandem mass spectrometric assay for the mutated BRAF inhibitor dabrafenib in mouse plasma.

Sparidans RW, Durmus S, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Apr 15;925:124-8. doi: 10.1016/j.jchromb.2013.02.025. Epub 2013 Feb 27.

PMID:
23537694
14.

A validated assay for the simultaneous quantification of six tyrosine kinase inhibitors and two active metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry.

van Erp NP, de Wit D, Guchelaar HJ, Gelderblom H, Hessing TJ, Hartigh Jd.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Oct 15;937:33-43. doi: 10.1016/j.jchromb.2013.08.013. Epub 2013 Aug 17.

PMID:
24013127
15.

Liquid chromatography-tandem mass spectrometric assay for the cyclin-dependent kinase inhibitor AT7519 in mouse plasma.

Dolman ME, den Hartog IJ, Molenaar JJ, Schellens JH, Beijnen JH, Sparidans RW.

J Pharm Biomed Anal. 2014 Jan;88:216-20. doi: 10.1016/j.jpba.2013.08.051. Epub 2013 Sep 12.

PMID:
24080524
16.

Liquid chromatography-tandem mass spectrometric assay for clobetasol propionate in human serum from patients with atopic dermatitis.

Sparidans RW, van Velsen SG, de Roos MP, Schellens JH, Bruijnzeel-Koomen CA, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Aug 1;878(23):2150-4. doi: 10.1016/j.jchromb.2010.06.011. Epub 2010 Jun 19.

PMID:
20605116
17.

Liquid chromatography-tandem mass spectrometric assay for the nucleoside reverse transcriptase inhibitor emtricitabine in human plasma.

Sparidans RW, Prins JM, Schellens JH, Beijnen JH.

Biomed Chromatogr. 2007 Jun;21(6):621-7.

PMID:
17340566
18.

Quantification of etravirine (TMC125) in plasma, dried blood spots and peripheral blood mononuclear cell lysate by liquid chromatography tandem mass spectrometry.

Ter Heine R, Rosing H, van Gorp EC, Mulder JW, Beijnen JH, Huitema AD.

J Pharm Biomed Anal. 2009 Feb 20;49(2):393-400. doi: 10.1016/j.jpba.2008.10.040. Epub 2008 Nov 5.

PMID:
19059744
19.

Liquid chromatography-tandem mass spectrometric assay for the PARP inhibitor rucaparib in plasma.

Sparidans RW, Durmus S, Schinkel AH, Schellens JH, Beijnen JH.

J Pharm Biomed Anal. 2014 Jan;88:626-9. doi: 10.1016/j.jpba.2013.10.016. Epub 2013 Oct 23.

PMID:
24216281
20.

Liquid chromatography-tandem mass spectrometry assay for the EGFR inhibitor pelitinib in plasma.

Luethi D, Durmus S, Schinkel AH, Schellens JH, Beijnen JH, Sparidans RW.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 1;934:22-5. doi: 10.1016/j.jchromb.2013.06.030. Epub 2013 Jul 4.

PMID:
23892825
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