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Items: 1 to 20 of 114

1.

HIF1α protein stability is increased by acetylation at lysine 709.

Geng H, Liu Q, Xue C, David LL, Beer TM, Thomas GV, Dai MS, Qian DZ.

J Biol Chem. 2012 Oct 12;287(42):35496-505. doi: 10.1074/jbc.M112.400697. Epub 2012 Aug 20.

2.

HDAC4 protein regulates HIF1α protein lysine acetylation and cancer cell response to hypoxia.

Geng H, Harvey CT, Pittsenbarger J, Liu Q, Beer TM, Xue C, Qian DZ.

J Biol Chem. 2011 Nov 4;286(44):38095-102. doi: 10.1074/jbc.M111.257055. Epub 2011 Sep 14.

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Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.

Ruas JL, Berchner-Pfannschmidt U, Malik S, Gradin K, Fandrey J, Roeder RG, Pereira T, Poellinger L.

J Biol Chem. 2010 Jan 22;285(4):2601-9. doi: 10.1074/jbc.M109.021824. Epub 2009 Oct 30.

6.

PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.

Xenaki G, Ontikatze T, Rajendran R, Stratford IJ, Dive C, Krstic-Demonacos M, Demonacos C.

Oncogene. 2008 Oct 2;27(44):5785-96. doi: 10.1038/onc.2008.192. Epub 2008 Jun 23.

7.

Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1.

Seo HW, Kim EJ, Na H, Lee MO.

FEBS Lett. 2009 Jan 5;583(1):55-60. doi: 10.1016/j.febslet.2008.11.044. Epub 2008 Dec 9.

8.

Acetylation at lysine 183 of progesterone receptor by p300 accelerates DNA binding kinetics and transactivation of direct target genes.

Chung HH, Sze SK, Tay AS, Lin VC.

J Biol Chem. 2014 Jan 24;289(4):2180-94. doi: 10.1074/jbc.M113.517896. Epub 2013 Dec 3.

9.

Acetylation of histone deacetylase 6 by p300 attenuates its deacetylase activity.

Han Y, Jeong HM, Jin YH, Kim YJ, Jeong HG, Yeo CY, Lee KY.

Biochem Biophys Res Commun. 2009 May 22;383(1):88-92. doi: 10.1016/j.bbrc.2009.03.147. Epub 2009 Apr 1.

PMID:
19344692
10.

A novel function of novobiocin: disrupting the interaction of HIF 1α and p300/CBP through direct binding to the HIF1α C-terminal activation domain.

Wu D, Zhang R, Zhao R, Chen G, Cai Y, Jin J.

PLoS One. 2013 May 6;8(5):e62014. doi: 10.1371/journal.pone.0062014. Print 2013.

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Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy.

Eom GH, Nam YS, Oh JG, Choe N, Min HK, Yoo EK, Kang G, Nguyen VH, Min JJ, Kim JK, Lee IK, Bassel-Duby R, Olson EN, Park WJ, Kook H.

Circ Res. 2014 Mar 28;114(7):1133-43. doi: 10.1161/CIRCRESAHA.114.303429. Epub 2014 Feb 13.

13.

Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity.

Kato H, Tamamizu-Kato S, Shibasaki F.

J Biol Chem. 2004 Oct 1;279(40):41966-74. Epub 2004 Jul 26.

14.

Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK.

Lin YY, Kiihl S, Suhail Y, Liu SY, Chou YH, Kuang Z, Lu JY, Khor CN, Lin CL, Bader JS, Irizarry R, Boeke JD.

Nature. 2012 Feb 8;482(7384):251-5. doi: 10.1038/nature10804. Retraction in: Nature. 2013 Nov 7;503(7474):146.

15.

Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cells.

Liu Q, Liu L, Zhao Y, Zhang J, Wang D, Chen J, He Y, Wu J, Zhang Z, Liu Z.

Mol Cancer Ther. 2011 Jun;10(6):1113-23. doi: 10.1158/1535-7163.MCT-10-1010. Epub 2011 Apr 1.

16.

Histone deacetylase 1 and p300 can directly associate with chromatin and compete for binding in a mutually exclusive manner.

Li X, Yang H, Huang S, Qiu Y.

PLoS One. 2014 Apr 10;9(4):e94523. doi: 10.1371/journal.pone.0094523. eCollection 2014.

17.

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

Kasper LH, Boussouar F, Boyd K, Xu W, Biesen M, Rehg J, Baudino TA, Cleveland JL, Brindle PK.

EMBO J. 2005 Nov 16;24(22):3846-58. Epub 2005 Oct 20.

18.

An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.

Stankovic-Valentin N, Deltour S, Seeler J, Pinte S, Vergoten G, Guérardel C, Dejean A, Leprince D.

Mol Cell Biol. 2007 Apr;27(7):2661-75. Epub 2007 Feb 5.

19.

Acetylation of Sirt2 by p300 attenuates its deacetylase activity.

Han Y, Jin YH, Kim YJ, Kang BY, Choi HJ, Kim DW, Yeo CY, Lee KY.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):576-80. doi: 10.1016/j.bbrc.2008.08.042. Epub 2008 Aug 21.

PMID:
18722353
20.

Id4 dependent acetylation restores mutant-p53 transcriptional activity.

Knowell AE, Patel D, Morton DJ, Sharma P, Glymph S, Chaudhary J.

Mol Cancer. 2013 Dec 13;12:161. doi: 10.1186/1476-4598-12-161.

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