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Items: 1 to 20 of 88

1.

The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin.

Gantner BN, Jin H, Qian F, Hay N, He B, Ye RD.

J Immunol. 2012 Sep 15;189(6):3104-11. doi: 10.4049/jimmunol.1201669. Epub 2012 Aug 17.

2.

Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1.

Joung SM, Park ZY, Rani S, Takeuchi O, Akira S, Lee JY.

J Immunol. 2011 Jan 1;186(1):499-507. doi: 10.4049/jimmunol.0903534. Epub 2010 Nov 24.

4.

Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4.

Doyle SE, O'Connell R, Vaidya SA, Chow EK, Yee K, Cheng G.

J Immunol. 2003 Apr 1;170(7):3565-71.

5.

Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-β and RANTES production.

Siednienko J, Gajanayake T, Fitzgerald KA, Moynagh P, Miggin SM.

J Immunol. 2011 Feb 15;186(4):2514-22. doi: 10.4049/jimmunol.1003093. Epub 2011 Jan 19.

6.

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response.

Lee KG, Xu S, Kang ZH, Huo J, Huang M, Liu D, Takeuchi O, Akira S, Lam KP.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5791-6. doi: 10.1073/pnas.1119238109. Epub 2012 Mar 27.

7.

Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.

Johnson J, Albarani V, Nguyen M, Goldman M, Willems F, Aksoy E.

J Biol Chem. 2007 May 18;282(20):15022-32. Epub 2007 Feb 12.

8.

Epithelial phosphatidylinositol-3-kinase signaling is required for β-catenin activation and host defense against Citrobacter rodentium infection.

Brown JB, Cheresh P, Goretsky T, Managlia E, Grimm GR, Ryu H, Zadeh M, Dirisina R, Barrett TA.

Infect Immun. 2011 May;79(5):1863-72. doi: 10.1128/IAI.01025-10. Epub 2011 Feb 22.

9.

Role of the Akt pathway in mRNA translation of interferon-stimulated genes.

Kaur S, Sassano A, Dolniak B, Joshi S, Majchrzak-Kita B, Baker DP, Hay N, Fish EN, Platanias LC.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4808-13. doi: 10.1073/pnas.0710907105. Epub 2008 Mar 13.

10.

IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism.

Stockinger S, Reutterer B, Schaljo B, Schellack C, Brunner S, Materna T, Yamamoto M, Akira S, Taniguchi T, Murray PJ, Müller M, Decker T.

J Immunol. 2004 Dec 15;173(12):7416-25.

11.

Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production.

Gabhann JN, Higgs R, Brennan K, Thomas W, Damen JE, Ben Larbi N, Krystal G, Jefferies CA.

J Immunol. 2010 Mar 1;184(5):2314-20. doi: 10.4049/jimmunol.0902589. Epub 2010 Jan 25.

12.
13.

Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.

Lee G, Goretsky T, Managlia E, Dirisina R, Singh AP, Brown JB, May R, Yang GY, Ragheb JW, Evers BM, Weber CR, Turner JR, He XC, Katzman RB, Li L, Barrett TA.

Gastroenterology. 2010 Sep;139(3):869-81, 881.e1-9. doi: 10.1053/j.gastro.2010.05.037. Epub 2010 May 24.

14.

Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.

Dong LW, Kong XN, Yan HX, Yu LX, Chen L, Yang W, Liu Q, Huang DD, Wu MC, Wang HY.

Mol Immunol. 2008 Jun;45(11):3025-35. doi: 10.1016/j.molimm.2008.03.012. Epub 2008 May 8.

PMID:
18471880
15.

Kainic acid-induced seizures modulate Akt (SER473) phosphorylation in the hippocampus of dopamine D2 receptor knockout mice.

Dunleavy M, Provenzano G, Henshall DC, Bozzi Y.

J Mol Neurosci. 2013 Jan;49(1):202-10. doi: 10.1007/s12031-012-9927-x. Epub 2012 Nov 29.

16.

Glycogen-Synthase Kinase3beta/beta-catenin axis promotes angiogenesis through activation of vascular endothelial growth factor signaling in endothelial cells.

Skurk C, Maatz H, Rocnik E, Bialik A, Force T, Walsh K.

Circ Res. 2005 Feb 18;96(3):308-18. Epub 2005 Jan 20.

17.

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction.

Sasai M, Shingai M, Funami K, Yoneyama M, Fujita T, Matsumoto M, Seya T.

J Immunol. 2006 Dec 15;177(12):8676-83.

18.

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker.

Jung DY, Lee H, Jung BY, Ock J, Lee MS, Lee WH, Suk K.

J Immunol. 2005 May 15;174(10):6467-76.

19.

Species-specific regulation of Toll-like receptor 3 genes in men and mice.

Heinz S, Haehnel V, Karaghiosoff M, Schwarzfischer L, Müller M, Krause SW, Rehli M.

J Biol Chem. 2003 Jun 13;278(24):21502-9. Epub 2003 Apr 2.

20.

Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: alternatively activated STAT1 negatively regulates TLR signaling in macrophages.

Schroder K, Spille M, Pilz A, Lattin J, Bode KA, Irvine KM, Burrows AD, Ravasi T, Weighardt H, Stacey KJ, Decker T, Hume DA, Dalpke AH, Sweet MJ.

J Immunol. 2007 Sep 15;179(6):3495-503.

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