Format
Items per page
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 112

1.

Inhibition of sumoylation prevents experimental fibrosis.

Khodzhigorova A, Distler A, Lang V, Dees C, Schneider H, Beyer C, Gelse K, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2012 Nov;71(11):1904-8. doi: 10.1136/annrheumdis-2012-201746. Epub 2012 Aug 17. Erratum in: Ann Rheum Dis. 2013 Jun;72(6):1110.

PMID:
22904261
2.

Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.

Tomcik M, Zerr P, Pitkowski J, Palumbo-Zerr K, Avouac J, Distler O, Becvar R, Senolt L, Schett G, Distler JH.

Ann Rheum Dis. 2014 Jun;73(6):1215-22. doi: 10.1136/annrheumdis-2012-203095. Epub 2013 May 9.

PMID:
23661493
3.

Vitamin D receptor regulates TGF-β signalling in systemic sclerosis.

Zerr P, Vollath S, Palumbo-Zerr K, Tomcik M, Huang J, Distler A, Beyer C, Dees C, Gela K, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2015 Mar;74(3):e20. doi: 10.1136/annrheumdis-2013-204378. Epub 2014 Jan 21.

PMID:
24448349
4.

The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.

Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheumatol. 2014 Nov;66(11):3140-50. doi: 10.1002/art.38819.

5.

Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.

Zhang Y, Dees C, Beyer C, Lin NY, Distler A, Zerr P, Palumbo K, Susok L, Kreuter A, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2015 May;74(5):936-43. doi: 10.1136/annrheumdis-2013-204256. Epub 2014 Jan 15.

PMID:
24431397
6.

Inactivation of evenness interrupted (EVI) reduces experimental fibrosis by combined inhibition of canonical and non-canonical Wnt signalling.

Distler A, Ziemer C, Beyer C, Lin NY, Chen CW, Palumbo-Zerr K, Dees C, Weidemann A, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2014 Mar;73(3):624-7. doi: 10.1136/annrheumdis-2013-203995. Epub 2013 Nov 20.

PMID:
24257024
7.

Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.

Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH.

Arthritis Rheum. 2012 May;64(5):1642-52. doi: 10.1002/art.33501.

8.

Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis.

Horn A, Kireva T, Palumbo-Zerr K, Dees C, Tomcik M, Cordazzo C, Zerr P, Akhmetshina A, Ruat M, Distler O, Beyer C, Schett G, Distler JH.

Ann Rheum Dis. 2012 May;71(5):785-9. doi: 10.1136/annrheumdis-2011-200883. Epub 2012 Mar 8.

PMID:
22402139
9.

Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling.

Distler A, Deloch L, Huang J, Dees C, Lin NY, Palumbo-Zerr K, Beyer C, Weidemann A, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 Sep 1;72(9):1575-80. doi: 10.1136/annrheumdis-2012-202275. Epub 2012 Nov 12.

PMID:
23148305
10.

S100A4 amplifies TGF-β-induced fibroblast activation in systemic sclerosis.

Tomcik M, Palumbo-Zerr K, Zerr P, Avouac J, Dees C, Sumova B, Distler A, Beyer C, Cerezo LA, Becvar R, Distler O, Grigorian M, Schett G, Senolt L, Distler JH.

Ann Rheum Dis. 2015 Sep;74(9):1748-55. doi: 10.1136/annrheumdis-2013-204516. Epub 2014 Apr 7.

PMID:
24709861
11.

Inhibition of glycogen synthase kinase 3β induces dermal fibrosis by activation of the canonical Wnt pathway.

Bergmann C, Akhmetshina A, Dees C, Palumbo K, Zerr P, Beyer C, Zwerina J, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2011 Dec;70(12):2191-8. doi: 10.1136/ard.2010.147140. Epub 2011 Aug 25.

PMID:
21873331
12.

Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis.

Reich N, Tomcik M, Zerr P, Lang V, Dees C, Avouac J, Palumbo K, Horn A, Akhmetshina A, Beyer C, Xie W, Bennett BL, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2012 May;71(5):737-45. doi: 10.1136/annrheumdis-2011-200412. Epub 2012 Jan 18.

PMID:
22258492
13.

Activation of pregnane X receptor inhibits experimental dermal fibrosis.

Beyer C, Skapenko A, Distler A, Dees C, Reichert H, Munoz L, Leipe J, Schulze-Koops H, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 Apr;72(4):621-5. doi: 10.1136/annrheumdis-2012-202476. Epub 2013 Jan 4.

PMID:
23291432
14.

Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.

Sonnylal S, Denton CP, Zheng B, Keene DR, He R, Adams HP, Vanpelt CS, Geng YJ, Deng JM, Behringer RR, de Crombrugghe B.

Arthritis Rheum. 2007 Jan;56(1):334-44.

15.

Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.

Lakos G, Takagawa S, Chen SJ, Ferreira AM, Han G, Masuda K, Wang XJ, DiPietro LA, Varga J.

Am J Pathol. 2004 Jul;165(1):203-17.

16.

Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis.

Zerr P, Palumbo-Zerr K, Huang J, Tomcik M, Sumova B, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2016 Jan;75(1):226-33. doi: 10.1136/annrheumdis-2014-205740. Epub 2014 Sep 1.

PMID:
25180292
17.

A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses.

Wei J, Zhu H, Komura K, Lord G, Tomcik M, Wang W, Doniparthi S, Tamaki Z, Hinchcliff M, Distler JH, Varga J.

Ann Rheum Dis. 2014 Feb;73(2):446-54. doi: 10.1136/annrheumdis-2012-202716. Epub 2013 Mar 20.

18.

Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis.

Huber LC, Distler JH, Moritz F, Hemmatazad H, Hauser T, Michel BA, Gay RE, Matucci-Cerinic M, Gay S, Distler O, Jüngel A.

Arthritis Rheum. 2007 Aug;56(8):2755-64.

19.

JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis.

Dees C, Tomcik M, Palumbo-Zerr K, Distler A, Beyer C, Lang V, Horn A, Zerr P, Zwerina J, Gelse K, Distler O, Schett G, Distler JH.

Arthritis Rheum. 2012 Sep;64(9):3006-15. doi: 10.1002/art.34500.

20.

Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis.

Distler JH, Jüngel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, Michel BA, Hauser T, Schett G, Gay S, Distler O.

Arthritis Rheum. 2007 Jan;56(1):311-22.

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk