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Results: 1 to 20 of 129

1.

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial.

Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, Ortega H, Chanez P.

Lancet. 2012 Aug 18;380(9842):651-9. doi: 10.1016/S0140-6736(12)60988-X.

PMID:
22901886
[PubMed - indexed for MEDLINE]
2.

Mepolizumab and exacerbations of refractory eosinophilic asthma.

Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, Sousa A, Marshall RP, Bradding P, Green RH, Wardlaw AJ, Pavord ID.

N Engl J Med. 2009 Mar 5;360(10):973-84. doi: 10.1056/NEJMoa0808991. Erratum in: N Engl J Med. 2011 Feb 10;364(6):588.

PMID:
19264686
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia.

Nair P, Pizzichini MM, Kjarsgaard M, Inman MD, Efthimiadis A, Pizzichini E, Hargreave FE, O'Byrne PM.

N Engl J Med. 2009 Mar 5;360(10):985-93. doi: 10.1056/NEJMoa0805435.

PMID:
19264687
[PubMed - indexed for MEDLINE]
Free Article
4.
5.

Efficacy of anti-interleukin-5 therapy with mepolizumab in patients with asthma: a meta-analysis of randomized placebo-controlled trials.

Liu Y, Zhang S, Li DW, Jiang SJ.

PLoS One. 2013;8(3):e59872. doi: 10.1371/journal.pone.0059872. Epub 2013 Mar 27. Erratum in: PLoS One. 2013;8(6). doi: 10.1371/annotation/8da4be4b-2de1-4c51-9c40-0f49dc212579.

PMID:
23544105
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma.

Ortega HG, Liu MC, Pavord ID, Brusselle GG, FitzGerald JM, Chetta A, Humbert M, Katz LE, Keene ON, Yancey SW, Chanez P; the MENSA Investigators.

N Engl J Med. 2014 Sep 8. [Epub ahead of print]

PMID:
25199059
[PubMed - as supplied by publisher]
Free Article
7.

A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.

Flood-Page P, Swenson C, Faiferman I, Matthews J, Williams M, Brannick L, Robinson D, Wenzel S, Busse W, Hansel TT, Barnes NC; International Mepolizumab Study Group.

Am J Respir Crit Care Med. 2007 Dec 1;176(11):1062-71. Epub 2007 Sep 13.

PMID:
17872493
[PubMed - indexed for MEDLINE]
8.

Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial.

Martinez FD, Chinchilli VM, Morgan WJ, Boehmer SJ, Lemanske RF Jr, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Friedman NJ, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Mellon MH, Sorkness CA, Taussig L.

Lancet. 2011 Feb 19;377(9766):650-7. doi: 10.1016/S0140-6736(10)62145-9. Epub 2011 Feb 14.

PMID:
21324520
[PubMed - indexed for MEDLINE]
9.

Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: a randomised, placebo-controlled, double-blind trial.

Straumann A, Conus S, Grzonka P, Kita H, Kephart G, Bussmann C, Beglinger C, Smith DA, Patel J, Byrne M, Simon HU.

Gut. 2010 Jan;59(1):21-30. doi: 10.1136/gut.2009.178558. Epub .

PMID:
19828470
[PubMed - indexed for MEDLINE]
10.

Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE.

Humbert M, Beasley R, Ayres J, Slavin R, H├ębert J, Bousquet J, Beeh KM, Ramos S, Canonica GW, Hedgecock S, Fox H, Blogg M, Surrey K.

Allergy. 2005 Mar;60(3):309-16.

PMID:
15679715
[PubMed - indexed for MEDLINE]
11.

Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study.

Brightling CE, Bleecker ER, Panettieri RA Jr, Bafadhel M, She D, Ward CK, Xu X, Birrell C, van der Merwe R.

Lancet Respir Med. 2014 Sep 5. pii: S2213-2600(14)70187-0. doi: 10.1016/S2213-2600(14)70187-0. [Epub ahead of print]

PMID:
25208464
[PubMed - as supplied by publisher]
12.

Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab).

Milgrom H, Berger W, Nayak A, Gupta N, Pollard S, McAlary M, Taylor AF, Rohane P.

Pediatrics. 2001 Aug;108(2):E36.

PMID:
11483846
[PubMed - indexed for MEDLINE]
13.

Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma.

Bel EH, Wenzel SE, Thompson PJ, Prazma CM, Keene ON, Yancey SW, Ortega HG, Pavord ID; the SIRIUS Investigators.

N Engl J Med. 2014 Sep 8. [Epub ahead of print]

PMID:
25199060
[PubMed - as supplied by publisher]
Free Article
14.

Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years.

Knorr B, Franchi LM, Bisgaard H, Vermeulen JH, LeSouef P, Santanello N, Michele TM, Reiss TF, Nguyen HH, Bratton DL.

Pediatrics. 2001 Sep;108(3):E48.

PMID:
11533366
[PubMed - indexed for MEDLINE]
15.

Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway.

Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS.

Am J Respir Crit Care Med. 2003 Jan 15;167(2):199-204. Epub 2002 Oct 17.

PMID:
12406833
[PubMed - indexed for MEDLINE]
16.

Sputum hyaluronan and versican in severe eosinophilic asthma.

Ayars AG, Altman LC, Potter-Perigo S, Radford K, Wight TN, Nair P.

Int Arch Allergy Immunol. 2013;161(1):65-73. doi: 10.1159/000343031. Epub 2012 Dec 14.

PMID:
23257685
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial.

Brusselle GG, Vanderstichele C, Jordens P, Deman R, Slabbynck H, Ringoet V, Verleden G, Demedts IK, Verhamme K, Delporte A, Demeyere B, Claeys G, Boelens J, Padalko E, Verschakelen J, Van Maele G, Deschepper E, Joos GF.

Thorax. 2013 Apr;68(4):322-9. doi: 10.1136/thoraxjnl-2012-202698. Epub 2013 Jan 3.

PMID:
23291349
[PubMed - indexed for MEDLINE]
18.

Treatment of patients with the hypereosinophilic syndrome with mepolizumab.

Rothenberg ME, Klion AD, Roufosse FE, Kahn JE, Weller PF, Simon HU, Schwartz LB, Rosenwasser LJ, Ring J, Griffin EF, Haig AE, Frewer PI, Parkin JM, Gleich GJ; Mepolizumab HES Study Group.

N Engl J Med. 2008 Mar 20;358(12):1215-28. doi: 10.1056/NEJMoa070812. Epub 2008 Mar 16. Erratum in: N Engl J Med. 2008 Jun 5;358(23): 2530.

PMID:
18344568
[PubMed - indexed for MEDLINE]
Free Article
19.

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia.

Laviolette M, Gossage DL, Gauvreau G, Leigh R, Olivenstein R, Katial R, Busse WW, Wenzel S, Wu Y, Datta V, Kolbeck R, Molfino NA.

J Allergy Clin Immunol. 2013 Nov;132(5):1086-1096.e5. doi: 10.1016/j.jaci.2013.05.020. Epub 2013 Jul 16. Erratum in: J Allergy Clin Immunol. 2014 Apr;133(4):1232.

PMID:
23866823
[PubMed - indexed for MEDLINE]
20.

Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): a randomised, double-blind, placebo-controlled trial.

Gold R, Giovannoni G, Selmaj K, Havrdova E, Montalban X, Radue EW, Stefoski D, Robinson R, Riester K, Rana J, Elkins J, O'Neill G; SELECT study investigators.

Lancet. 2013 Jun 22;381(9884):2167-75. doi: 10.1016/S0140-6736(12)62190-4. Epub 2013 Apr 4.

PMID:
23562009
[PubMed - indexed for MEDLINE]

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