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Results: 1 to 20 of 102

1.

Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A.

Carpenter MA, Li M, Rathore A, Lackey L, Law EK, Land AM, Leonard B, Shandilya SM, Bohn MF, Schiffer CA, Brown WL, Harris RS.

J Biol Chem. 2012 Oct 5;287(41):34801-8. doi: 10.1074/jbc.M112.385161. Epub 2012 Aug 15.

PMID:
22896697
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G.

Wijesinghe P, Bhagwat AS.

Nucleic Acids Res. 2012 Oct;40(18):9206-17. doi: 10.1093/nar/gks685. Epub 2012 Jul 13.

PMID:
22798497
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.

Aynaud MM, Suspène R, Vidalain PO, Mussil B, Guétard D, Tangy F, Wain-Hobson S, Vartanian JP.

J Biol Chem. 2012 Nov 9;287(46):39182-92. doi: 10.1074/jbc.M112.372722. Epub 2012 Sep 13.

PMID:
22977230
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Endogenous APOBEC3A DNA cytosine deaminase is cytoplasmic and nongenotoxic.

Land AM, Law EK, Carpenter MA, Lackey L, Brown WL, Harris RS.

J Biol Chem. 2013 Jun 14;288(24):17253-60. doi: 10.1074/jbc.M113.458661. Epub 2013 May 2.

PMID:
23640892
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase.

Suspène R, Aynaud MM, Vartanian JP, Wain-Hobson S.

PLoS One. 2013 Jun 20;8(6):e63461. doi: 10.1371/journal.pone.0063461. Print 2013.

PMID:
23840298
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

APOBEC3 proteins mediate the clearance of foreign DNA from human cells.

Stenglein MD, Burns MB, Li M, Lengyel J, Harris RS.

Nat Struct Mol Biol. 2010 Feb;17(2):222-9. doi: 10.1038/nsmb.1744. Epub 2010 Jan 10.

PMID:
20062055
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Structure-function analyses point to a polynucleotide-accommodating groove essential for APOBEC3A restriction activities.

Bulliard Y, Narvaiza I, Bertero A, Peddi S, Röhrig UF, Ortiz M, Zoete V, Castro-Díaz N, Turelli P, Telenti A, Michielin O, Weitzman MD, Trono D.

J Virol. 2011 Feb;85(4):1765-76. doi: 10.1128/JVI.01651-10. Epub 2010 Dec 1.

PMID:
21123384
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Biochemical analysis of hypermutation by the deoxycytidine deaminase APOBEC3A.

Love RP, Xu H, Chelico L.

J Biol Chem. 2012 Aug 31;287(36):30812-22. doi: 10.1074/jbc.M112.393181. Epub 2012 Jul 20.

PMID:
22822074
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms.

Thielen BK, McNevin JP, McElrath MJ, Hunt BV, Klein KC, Lingappa JR.

J Biol Chem. 2010 Sep 3;285(36):27753-66. doi: 10.1074/jbc.M110.102822. Epub 2010 Jul 8.

PMID:
20615867
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1).

Petersen-Mahrt SK, Neuberger MS.

J Biol Chem. 2003 May 30;278(22):19583-6. Epub 2003 Apr 14.

PMID:
12697753
[PubMed - indexed for MEDLINE]
Free Article
11.

AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.

Nabel CS, Jia H, Ye Y, Shen L, Goldschmidt HL, Stivers JT, Zhang Y, Kohli RM.

Nat Chem Biol. 2012 Sep;8(9):751-8. doi: 10.1038/nchembio.1042. Epub 2012 Jul 8.

PMID:
22772155
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity.

Byeon IJ, Ahn J, Mitra M, Byeon CH, Hercík K, Hritz J, Charlton LM, Levin JG, Gronenborn AM.

Nat Commun. 2013;4:1890. doi: 10.1038/ncomms2883.

PMID:
23695684
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution.

Rathore A, Carpenter MA, Demir Ö, Ikeda T, Li M, Shaban NM, Law EK, Anokhin D, Brown WL, Amaro RE, Harris RS.

J Mol Biol. 2013 Nov 15;425(22):4442-54. doi: 10.1016/j.jmb.2013.07.040. Epub 2013 Aug 11.

PMID:
23938202
[PubMed - indexed for MEDLINE]
14.

Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.

Mitra M, Hercík K, Byeon IJ, Ahn J, Hill S, Hinchee-Rodriguez K, Singer D, Byeon CH, Charlton LM, Nam G, Heidecker G, Gronenborn AM, Levin JG.

Nucleic Acids Res. 2014 Jan;42(2):1095-110. doi: 10.1093/nar/gkt945. Epub 2013 Oct 24.

PMID:
24163103
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Dissecting APOBEC3G substrate specificity by nucleoside analog interference.

Rausch JW, Chelico L, Goodman MF, Le Grice SF.

J Biol Chem. 2009 Mar 13;284(11):7047-58. doi: 10.1074/jbc.M807258200. Epub 2009 Jan 9.

PMID:
19136562
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming.

Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK.

J Biol Chem. 2004 Dec 10;279(50):52353-60. Epub 2004 Sep 24.

PMID:
15448152
[PubMed - indexed for MEDLINE]
Free Article
17.

DNA deamination in immunity: AID in the context of its APOBEC relatives.

Conticello SG, Langlois MA, Yang Z, Neuberger MS.

Adv Immunol. 2007;94:37-73. Review.

PMID:
17560271
[PubMed - indexed for MEDLINE]
19.

Local sequence targeting in the AID/APOBEC family differentially impacts retroviral restriction and antibody diversification.

Kohli RM, Maul RW, Guminski AF, McClure RL, Gajula KS, Saribasak H, McMahon MA, Siliciano RF, Gearhart PJ, Stivers JT.

J Biol Chem. 2010 Dec 24;285(52):40956-64. doi: 10.1074/jbc.M110.177402. Epub 2010 Oct 6.

PMID:
20929867
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1.

Ooms M, Krikoni A, Kress AK, Simon V, Münk C.

J Virol. 2012 Jun;86(11):6097-108. doi: 10.1128/JVI.06570-11. Epub 2012 Mar 28.

PMID:
22457529
[PubMed - indexed for MEDLINE]
Free PMC Article

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