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Items: 1 to 20 of 84

1.

Proteasome inhibition alleviates SNARE-dependent neurodegeneration.

Sharma M, Burré J, Südhof TC.

Sci Transl Med. 2012 Aug 15;4(147):147ra113. doi: 10.1126/scitranslmed.3004028.

2.

CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.

Sharma M, Burré J, Südhof TC.

Nat Cell Biol. 2011 Jan;13(1):30-9. doi: 10.1038/ncb2131. Epub 2010 Dec 12. Erratum in: Nat Cell Biol. 2011 Feb;13(2):182.

PMID:
21151134
3.

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration.

Chandra S, Gallardo G, Fernández-Chacón R, Schlüter OM, Südhof TC.

Cell. 2005 Nov 4;123(3):383-96.

4.

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.

Burré J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC.

Science. 2010 Sep 24;329(5999):1663-7. doi: 10.1126/science.1195227. Epub 2010 Aug 26.

5.

Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses.

Ninkina N, Peters OM, Connor-Robson N, Lytkina O, Sharfeddin E, Buchman VL.

J Biol Chem. 2012 Dec 28;287(53):44471-7. doi: 10.1074/jbc.M112.422402. Epub 2012 Nov 5.

6.

CSPα knockout causes neurodegeneration by impairing SNAP-25 function.

Sharma M, Burré J, Bronk P, Zhang Y, Xu W, Südhof TC.

EMBO J. 2012 Feb 15;31(4):829-41. doi: 10.1038/emboj.2011.467. Epub 2011 Dec 20.

7.

The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease.

McNaught KS, Jnobaptiste R, Jackson T, Jengelley TA.

Synapse. 2010 Mar;64(3):241-50. doi: 10.1002/syn.20719.

PMID:
19924695
8.

Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease.

Tiwari SS, d'Orange M, Troakes C, Shurovi BN, Engmann O, Noble W, Hortobágyi T, Giese KP.

Mol Brain. 2015 Jan 29;8:6. doi: 10.1186/s13041-015-0096-z.

9.

Chaperoning the SNAREs: a role in preventing neurodegeneration?

Burgoyne RD, Morgan A.

Nat Cell Biol. 2011 Jan;13(1):8-9. doi: 10.1038/ncb0111-8.

PMID:
21173802
10.

Proteasome inhibitor MG-132 induces dopaminergic degeneration in cell culture and animal models.

Sun F, Anantharam V, Zhang D, Latchoumycandane C, Kanthasamy A, Kanthasamy AG.

Neurotoxicology. 2006 Sep;27(5):807-15. Epub 2006 Jun 29.

PMID:
16870259
11.

A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.

Gallardo G, Schlüter OM, Südhof TC.

Nat Neurosci. 2008 Mar;11(3):301-8. doi: 10.1038/nn2058. Epub 2008 Feb 24.

PMID:
18297066
12.

The role of ubiquitin linkages on alpha-synuclein induced-toxicity in a Drosophila model of Parkinson's disease.

Lee FK, Wong AK, Lee YW, Wan OW, Chan HY, Chung KK.

J Neurochem. 2009 Jul;110(1):208-19. doi: 10.1111/j.1471-4159.2009.06124.x. Epub 2009 Apr 27.

13.

Heat shock proteins reduce alpha-synuclein aggregation induced by MPP+ in SK-N-SH cells.

Fan GH, Zhou HY, Yang H, Chen SD.

FEBS Lett. 2006 May 29;580(13):3091-8. Epub 2006 Apr 27.

14.

The cysteine string protein multimeric complex.

Swayne LA, Beck KE, Braun JE.

Biochem Biophys Res Commun. 2006 Sep 15;348(1):83-91. Epub 2006 Jul 17.

PMID:
16875662
15.

Proteasome inhibition modeling nigral neuron degeneration in Parkinson's disease.

Xie W, Li X, Li C, Zhu W, Jankovic J, Le W.

J Neurochem. 2010 Oct;115(1):188-99. doi: 10.1111/j.1471-4159.2010.06914.x. Epub 2010 Aug 19.

16.

Identification of CSPα clients reveals a role in dynamin 1 regulation.

Zhang YQ, Henderson MX, Colangelo CM, Ginsberg SD, Bruce C, Wu T, Chandra SS.

Neuron. 2012 Apr 12;74(1):136-50. doi: 10.1016/j.neuron.2012.01.029.

17.

New therapeutic strategy for Parkinson's and Alzheimer's disease.

Esposito E, Cuzzocrea S.

Curr Med Chem. 2010;17(25):2764-74. Review.

PMID:
20586718
18.

Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration.

Paine S, Bedford L, Thorpe JR, Mayer RJ, Cavey JR, Bajaj N, Sheppard PW, Lowe J, Layfield R.

Neurosci Lett. 2009 Sep 4;460(3):205-8. doi: 10.1016/j.neulet.2009.05.074. Epub 2009 Jun 7.

PMID:
19500650
20.

Postnatal proteasome inhibition induces neurodegeneration and cognitive deficiencies in adult mice: a new model of neurodevelopment syndrome.

Romero-Granados R, Fontán-Lozano Á, Aguilar-Montilla FJ, Carrión ÁM.

PLoS One. 2011;6(12):e28927. doi: 10.1371/journal.pone.0028927. Epub 2011 Dec 12.

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