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Metabolic effects of intermittent hypoxia in mice: steady versus high-frequency applied hypoxia daily during the rest period.

Carreras A, Kayali F, Zhang J, Hirotsu C, Wang Y, Gozal D.

Am J Physiol Regul Integr Comp Physiol. 2012 Oct 1;303(7):R700-9. doi: 10.1152/ajpregu.00258.2012. Epub 2012 Aug 15.


Effects of different acute hypoxic regimens on tissue oxygen profiles and metabolic outcomes.

Reinke C, Bevans-Fonti S, Drager LF, Shin MK, Polotsky VY.

J Appl Physiol (1985). 2011 Sep;111(3):881-90. doi: 10.1152/japplphysiol.00492.2011. Epub 2011 Jul 7.


Effect of prolonged intermittent hypoxia and exercise training on glucose tolerance and muscle GLUT4 protein expression in rats.

Chiu LL, Chou SW, Cho YM, Ho HY, Ivy JL, Hunt D, Wang PS, Kuo CH.

J Biomed Sci. 2004 Nov-Dec;11(6):838-46.


Chronic hypoxia increases insulin-stimulated glucose uptake in mouse soleus muscle.

Gamboa JL, Garcia-Cazarin ML, Andrade FH.

Am J Physiol Regul Integr Comp Physiol. 2011 Jan;300(1):R85-91. doi: 10.1152/ajpregu.00078.2010. Epub 2010 Oct 20.


Time-dependent changes in glucose and insulin regulation during intermittent hypoxia and continuous hypoxia.

Lee EJ, Alonso LC, Stefanovski D, Strollo HC, Romano LC, Zou B, Singamsetty S, Yester KA, McGaffin KR, Garcia-Ocana A, O'Donnell CP.

Eur J Appl Physiol. 2013 Feb;113(2):467-78. doi: 10.1007/s00421-012-2452-3. Epub 2012 Jul 17.


Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in mice.

Yokoe T, Alonso LC, Romano LC, Rosa TC, O'Doherty RM, Garcia-Ocana A, Minoguchi K, O'Donnell CP.

J Physiol. 2008 Feb 1;586(3):899-911. Epub 2007 Nov 22.


Carotid body denervation prevents fasting hyperglycemia during chronic intermittent hypoxia.

Shin MK, Yao Q, Jun JC, Bevans-Fonti S, Yoo DY, Han W, Mesarwi O, Richardson R, Fu YY, Pasricha PJ, Schwartz AR, Shirahata M, Polotsky VY.

J Appl Physiol (1985). 2014 Oct 1;117(7):765-76. doi: 10.1152/japplphysiol.01133.2013. Epub 2014 Aug 7.


Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1alpha.

Li J, Bosch-Marce M, Nanayakkara A, Savransky V, Fried SK, Semenza GL, Polotsky VY.

Physiol Genomics. 2006 May 16;25(3):450-7. Epub 2006 Feb 28.


Resveratrol attenuates intermittent hypoxia-induced macrophage migration to visceral white adipose tissue and insulin resistance in male mice.

Carreras A, Zhang SX, Almendros I, Wang Y, Peris E, Qiao Z, Gozal D.

Endocrinology. 2015 Feb;156(2):437-43. doi: 10.1210/en.2014-1706. Epub 2014 Nov 18.


Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity.

Iiyori N, Alonso LC, Li J, Sanders MH, Garcia-Ocana A, O'Doherty RM, Polotsky VY, O'Donnell CP.

Am J Respir Crit Care Med. 2007 Apr 15;175(8):851-7. Epub 2007 Feb 1.


Intermittent hypoxia and diet-induced obesity: effects on oxidative status, sympathetic tone, plasma glucose and insulin levels, and arterial pressure.

Olea E, Agapito MT, Gallego-Martin T, Rocher A, Gomez-NiƱo A, Obeso A, Gonzalez C, Yubero S.

J Appl Physiol (1985). 2014 Oct 1;117(7):706-19. doi: 10.1152/japplphysiol.00454.2014. Epub 2014 Aug 7.


Dim light at night interacts with intermittent hypoxia to alter cognitive and affective responses.

Aubrecht TG, Weil ZM, Magalang UJ, Nelson RJ.

Am J Physiol Regul Integr Comp Physiol. 2013 Jul 1;305(1):R78-86. doi: 10.1152/ajpregu.00100.2013. Epub 2013 May 8.


Inflammation status of rabbit carotid artery model endothelium during intermittent hypoxia exposure and its relationship with leptin.

Feng J, Chen BY, Cui LY, Wang BL, Liu CX, Chen PF, Guo MN, Dong LX, Li S.

Sleep Breath. 2009 Aug;13(3):277-83. doi: 10.1007/s11325-009-0246-6. Epub 2009 Mar 17.


Platelet-activating factor receptor modulates respiratory adaptation to long-term intermittent hypoxia in mice.

Reeves SR, Gozal D.

Am J Physiol Regul Integr Comp Physiol. 2004 Aug;287(2):R369-74. Epub 2004 Apr 15.


Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice.

Naghshin J, McGaffin KR, Witham WG, Mathier MA, Romano LC, Smith SH, Janczewski AM, Kirk JA, Shroff SG, O'Donnell CP.

J Appl Physiol (1985). 2009 Sep;107(3):787-93. doi: 10.1152/japplphysiol.91256.2008. Epub 2009 Jul 9.


The effect of adrenal medullectomy on metabolic responses to chronic intermittent hypoxia.

Shin MK, Han W, Bevans-Fonti S, Jun JC, Punjabi NM, Polotsky VY.

Respir Physiol Neurobiol. 2014 Nov 1;203:60-7. doi: 10.1016/j.resp.2014.08.018. Epub 2014 Aug 29.


Interaction between BTBR and C57BL/6J genomes produces an insulin resistance syndrome in (BTBR x C57BL/6J) F1 mice.

Ranheim T, Dumke C, Schueler KL, Cartee GD, Attie AD.

Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):3286-93.


Intermittent hypoxia increases insulin resistance in genetically obese mice.

Polotsky VY, Li J, Punjabi NM, Rubin AE, Smith PL, Schwartz AR, O'Donnell CP.

J Physiol. 2003 Oct 1;552(Pt 1):253-64. Epub 2003 Jul 23.


Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia.

Li J, Nanayakkara A, Jun J, Savransky V, Polotsky VY.

Physiol Genomics. 2007 Oct 22;31(2):273-80. Epub 2007 Jul 31.

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