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Results: 1 to 20 of 103

1.

β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury.

Kim KS, Abraham D, Williams B, Violin JD, Mao L, Rockman HA.

Am J Physiol Heart Circ Physiol. 2012 Oct 15;303(8):H1001-10. doi: 10.1152/ajpheart.00475.2012. Epub 2012 Aug 10.

PMID:
22886417
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium.

Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ.

Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H856-66. doi: 10.1152/ajpheart.00327.2013. Epub 2013 Jul 19.

PMID:
23873795
[PubMed - indexed for MEDLINE]
3.

Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

Violin JD, DeWire SM, Yamashita D, Rominger DH, Nguyen L, Schiller K, Whalen EJ, Gowen M, Lark MW.

J Pharmacol Exp Ther. 2010 Dec;335(3):572-9. doi: 10.1124/jpet.110.173005. Epub 2010 Aug 26.

PMID:
20801892
[PubMed - indexed for MEDLINE]
Free Article
4.

Tissue kallikrein is involved in the cardioprotective effect of AT1-receptor blockade in acute myocardial ischemia.

Messadi-Laribi E, Griol-Charhbili V, Pizard A, Vincent MP, Heudes D, Meneton P, Alhenc-Gelas F, Richer C.

J Pharmacol Exp Ther. 2007 Oct;323(1):210-6. Epub 2007 Jul 16.

PMID:
17636004
[PubMed - indexed for MEDLINE]
Free Article
5.

Cardiorenal actions of TRV120027, a novel ß-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: a novel therapeutic strategy for acute heart failure.

Boerrigter G, Lark MW, Whalen EJ, Soergel DG, Violin JD, Burnett JC Jr.

Circ Heart Fail. 2011 Nov;4(6):770-8. doi: 10.1161/CIRCHEARTFAILURE.111.962571. Epub 2011 Aug 11.

PMID:
21835984
[PubMed - indexed for MEDLINE]
Free Article
6.

TRV120027, a novel β-arrestin biased ligand at the angiotensin II type I receptor, unloads the heart and maintains renal function when added to furosemide in experimental heart failure.

Boerrigter G, Soergel DG, Violin JD, Lark MW, Burnett JC Jr.

Circ Heart Fail. 2012 Sep 1;5(5):627-34. Epub 2012 Aug 13.

PMID:
22891045
[PubMed - indexed for MEDLINE]
Free Article
7.

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes.

Rajagopal K, Whalen EJ, Violin JD, Stiber JA, Rosenberg PB, Premont RT, Coffman TM, Rockman HA, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16284-9. Epub 2006 Oct 23.

PMID:
17060617
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.

Zhao Y, Chen X, Cai L, Yang Y, Sui G, Fu S.

J Cell Physiol. 2010 Oct;225(1):168-73. doi: 10.1002/jcp.22209.

PMID:
20458733
[PubMed - indexed for MEDLINE]
9.
10.

The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling.

Bonde MM, Olsen KB, Erikstrup N, Speerschneider T, Lyngsø C, Haunsø S, Nielsen MS, Sheikh SP, Hansen JL.

Regul Pept. 2011 Feb 25;167(1):21-5. doi: 10.1016/j.regpep.2010.11.003. Epub 2010 Nov 27.

PMID:
21115072
[PubMed - indexed for MEDLINE]
11.

Angiotensin II type 2 receptors contribute to vascular responses in spontaneously hypertensive rats treated with angiotensin II type 1 receptor antagonists.

Cosentino F, Savoia C, De Paolis P, Francia P, Russo A, Maffei A, Venturelli V, Schiavoni M, Lembo G, Volpe M.

Am J Hypertens. 2005 Apr;18(4 Pt 1):493-9.

PMID:
15831358
[PubMed - indexed for MEDLINE]
12.

Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice.

Patel VB, Bodiga S, Fan D, Das SK, Wang Z, Wang W, Basu R, Zhong J, Kassiri Z, Oudit GY.

Hypertension. 2012 Jun;59(6):1195-203. doi: 10.1161/HYPERTENSIONAHA.112.191650. Epub 2012 Apr 16.

PMID:
22508831
[PubMed - indexed for MEDLINE]
Free Article
13.

beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress.

Rakesh K, Yoo B, Kim IM, Salazar N, Kim KS, Rockman HA.

Sci Signal. 2010 Jun 8;3(125):ra46. doi: 10.1126/scisignal.2000769.

PMID:
20530803
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Induction of cardiac fibrosis by β-blocker in G protein-independent and G protein-coupled receptor kinase 5/β-arrestin2-dependent Signaling pathways.

Nakaya M, Chikura S, Watari K, Mizuno N, Mochinaga K, Mangmool S, Koyanagi S, Ohdo S, Sato Y, Ide T, Nishida M, Kurose H.

J Biol Chem. 2012 Oct 12;287(42):35669-77. doi: 10.1074/jbc.M112.357871. Epub 2012 Aug 10.

PMID:
22888001
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs.

Zimmerman B, Beautrait A, Aguila B, Charles R, Escher E, Claing A, Bouvier M, Laporte SA.

Sci Signal. 2012 Apr 24;5(221):ra33. doi: 10.1126/scisignal.2002522.

PMID:
22534132
[PubMed - indexed for MEDLINE]
Free Article
16.

Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension.

Calò LA, Schiavo S, Davis PA, Pagnin E, Mormino P, D'Angelo A, Pessina AC.

J Hypertens. 2010 Jan;28(1):111-8. doi: 10.1097/HJH.0b013e328332b738.

PMID:
19797979
[PubMed - indexed for MEDLINE]
17.

Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling.

Seki K, Sanada S, Kudinova AY, Steinhauser ML, Handa V, Gannon J, Lee RT.

Circ Heart Fail. 2009 Nov;2(6):684-91. doi: 10.1161/CIRCHEARTFAILURE.109.873240. Epub 2009 Sep 22.

PMID:
19919994
[PubMed - indexed for MEDLINE]
Free Article
18.

Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms.

Bathgate-Siryk A, Dabul S, Pandya K, Walklett K, Rengo G, Cannavo A, De Lucia C, Liccardo D, Gao E, Leosco D, Koch WJ, Lymperopoulos A.

Hypertension. 2014 Feb;63(2):404-12. doi: 10.1161/HYPERTENSIONAHA.113.02043. Epub 2013 Nov 11.

PMID:
24218435
[PubMed - indexed for MEDLINE]
19.

Biased agonism of the angiotensin II type 1 receptor.

Godin CM, Ferguson SS.

Mini Rev Med Chem. 2012 Aug;12(9):812-6. Review.

PMID:
22681254
[PubMed - indexed for MEDLINE]
20.

Biased signaling of the angiotensin II type 1 receptor can be mediated through distinct mechanisms.

Bonde MM, Hansen JT, Sanni SJ, Haunsø S, Gammeltoft S, Lyngsø C, Hansen JL.

PLoS One. 2010 Nov 30;5(11):e14135. doi: 10.1371/journal.pone.0014135.

PMID:
21152433
[PubMed - indexed for MEDLINE]
Free PMC Article

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