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Results: 1 to 20 of 113

1.

Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice.

Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI 2nd, Harris RA.

Anesthesiology. 2012 Oct;117(4):765-71.

PMID:
22885675
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.

Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA.

J Pharmacol Exp Ther. 2012 Feb;340(2):304-16. doi: 10.1124/jpet.111.185116. Epub 2011 Oct 28.

PMID:
22037201
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Glycine receptors mediate part of the immobility produced by inhaled anesthetics.

Zhang Y, Laster MJ, Hara K, Harris RA, Eger EI 2nd, Stabernack CR, Sonner JM.

Anesth Analg. 2003 Jan;96(1):97-101, table of contents.

PMID:
12505932
[PubMed - indexed for MEDLINE]
4.

Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes.

Downie DL, Hall AC, Lieb WR, Franks NP.

Br J Pharmacol. 1996 Jun;118(3):493-502.

PMID:
8762070
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The anesthetic-like effects of diverse compounds on wild-type and mutant gamma-aminobutyric acid type A and glycine receptors.

Yang L, Sonner JM.

Anesth Analg. 2008 Mar;106(3):838-45, table of contents. doi: 10.1213/ane.0b013e31816095bd.

PMID:
18292428
[PubMed - indexed for MEDLINE]
6.

Divergence of volatile anesthetic effects in inhibitory neurotransmitter receptors.

Greenblatt EP, Meng X.

Anesthesiology. 2001 Jun;94(6):1026-33.

PMID:
11465594
[PubMed - indexed for MEDLINE]
Free Article
7.

Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane.

Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI 2nd.

Anesth Analg. 2005 Aug;101(2):412-8, table of contents.

PMID:
16037154
[PubMed - indexed for MEDLINE]
8.
9.

Isoflurane depression of spinal nociceptive processing and minimum alveolar anesthetic concentration are not attenuated in mice expressing isoflurane resistant gamma-aminobutyric acid type-A receptors.

Kim J, Atherley R, Werner DF, Homanics GE, Carstens E, Antognini JF.

Neurosci Lett. 2007 Jun 15;420(3):209-12. Epub 2007 Apr 29.

PMID:
17543455
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.

O'Shea SM, Becker L, Weiher H, Betz H, Laube B.

J Neurosci. 2004 Mar 3;24(9):2322-7.

PMID:
14999083
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Subunit-dependent block by isoflurane of wild-type and mutant alpha(1)S270H GABA(A) receptor currents in Xenopus oocytes.

Hall AC, Stevens RJ, Betts BA, Yeung WY, Kelley JC, Harrison NL.

Neurosci Lett. 2005 Jul 15;382(3):332-7. Epub 2005 Apr 14.

PMID:
15925114
[PubMed - indexed for MEDLINE]
13.

Anesthetic and ethanol effects on spontaneously opening glycine receptor channels.

Beckstead MJ, Phelan R, Trudell JR, Bianchini MJ, Mihic SJ.

J Neurochem. 2002 Sep;82(6):1343-51.

PMID:
12354281
[PubMed - indexed for MEDLINE]
14.

Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.

Blednov YA, Benavidez JM, Homanics GE, Harris RA.

J Pharmacol Exp Ther. 2012 Feb;340(2):317-29. doi: 10.1124/jpet.111.185124. Epub 2011 Oct 28.

PMID:
22037202
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Isovaleric, methylmalonic, and propionic acid decrease anesthetic EC50 in tadpoles, modulate glycine receptor function, and interact with the lipid 1,2-dipalmitoyl-Sn-glycero-3-phosphocholine.

Weng Y, Hsu TT, Zhao J, Nishimura S, Fuller GG, Sonner JM.

Anesth Analg. 2009 May;108(5):1538-45. doi: 10.1213/ane.0b013e31819cd964.

PMID:
19372333
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The effect of three inhaled anesthetics in mice harboring mutations in the GluR6 (kainate) receptor gene.

Sonner JM, Vissel B, Royle G, Maurer A, Gong D, Baron NV, Harrison N, Fanselow M, Eger EI 2nd.

Anesth Analg. 2005 Jul;101(1):143-8, table of contents.

PMID:
15976221
[PubMed - indexed for MEDLINE]
17.

Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane.

Zhang Y, Sonner JM, Eger EI 2nd, Stabernack CR, Laster MJ, Raines DE, Harris RA.

Anesth Analg. 2004 Jul;99(1):85-90.

PMID:
15281509
[PubMed - indexed for MEDLINE]
18.

Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels. Comparison with isoflurane and ethanol.

Yamakura T, Harris RA.

Anesthesiology. 2000 Oct;93(4):1095-101.

PMID:
11020766
[PubMed - indexed for MEDLINE]
Free Article
19.

Differential sensitivity of expressed L-type calcium channels and muscarinic M(1) receptors to volatile anesthetics in Xenopus oocytes.

Kamatchi GL, Durieux ME, Lynch C 3rd.

J Pharmacol Exp Ther. 2001 Jun;297(3):981-90.

PMID:
11356920
[PubMed - indexed for MEDLINE]
Free Article
20.

Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane.

Sonner JM, Werner DF, Elsen FP, Xing Y, Liao M, Harris RA, Harrison NL, Fanselow MS, Eger EI 2nd, Homanics GE.

Anesthesiology. 2007 Jan;106(1):107-13.

PMID:
17197852
[PubMed - indexed for MEDLINE]
Free Article

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