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Items: 1 to 20 of 249

1.

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy.

Kraft C, Kijanska M, Kalie E, Siergiejuk E, Lee SS, Semplicio G, Stoffel I, Brezovich A, Verma M, Hansmann I, Ammerer G, Hofmann K, Tooze S, Peter M.

EMBO J. 2012 Sep 12;31(18):3691-703. doi: 10.1038/emboj.2012.225. Epub 2012 Aug 10.

2.

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy.

Mercer CA, Kaliappan A, Dennis PB.

Autophagy. 2009 Jul;5(5):649-62. Epub 2009 Jul 20.

PMID:
19287211
3.

An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation.

Chang YY, Neufeld TP.

Mol Biol Cell. 2009 Apr;20(7):2004-14. doi: 10.1091/mbc.E08-12-1250. Epub 2009 Feb 18.

4.

ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

Alemu EA, Lamark T, Torgersen KM, Birgisdottir AB, Larsen KB, Jain A, Olsvik H, Øvervatn A, Kirkin V, Johansen T.

J Biol Chem. 2012 Nov 16;287(47):39275-90. doi: 10.1074/jbc.M112.378109. Epub 2012 Oct 5.

5.

ATG13: just a companion, or an executor of the autophagic program?

Alers S, Wesselborg S, Stork B.

Autophagy. 2014 Jun;10(6):944-56. doi: 10.4161/auto.28987. Review. Erratum in: Autophagy. 2014 Aug;10(8):1481.

6.

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.

Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N.

Mol Biol Cell. 2009 Apr;20(7):1981-91. doi: 10.1091/mbc.E08-12-1248. Epub 2009 Feb 11.

7.

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.

Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH.

Mol Biol Cell. 2009 Apr;20(7):1992-2003. doi: 10.1091/mbc.E08-12-1249. Epub 2009 Feb 18.

8.

The autophagy-related protein kinase Atg1 interacts with the ubiquitin-like protein Atg8 via the Atg8 family interacting motif to facilitate autophagosome formation.

Nakatogawa H, Ohbayashi S, Sakoh-Nakatogawa M, Kakuta S, Suzuki SW, Kirisako H, Kondo-Kakuta C, Noda NN, Yamamoto H, Ohsumi Y.

J Biol Chem. 2012 Aug 17;287(34):28503-7. doi: 10.1074/jbc.C112.387514. Epub 2012 Jul 9.

9.

The association of AMPK with ULK1 regulates autophagy.

Lee JW, Park S, Takahashi Y, Wang HG.

PLoS One. 2010 Nov 3;5(11):e15394. doi: 10.1371/journal.pone.0015394.

10.

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR.

Egan D, Kim J, Shaw RJ, Guan KL.

Autophagy. 2011 Jun;7(6):643-4. Epub 2011 Jun 1.

11.

Dynamic association of the ULK1 complex with omegasomes during autophagy induction.

Karanasios E, Stapleton E, Manifava M, Kaizuka T, Mizushima N, Walker SA, Ktistakis NT.

J Cell Sci. 2013 Nov 15;126(Pt 22):5224-38. doi: 10.1242/jcs.132415. Epub 2013 Sep 6.

12.

The ATG1/ATG13 protein kinase complex is both a regulator and a target of autophagic recycling in Arabidopsis.

Suttangkakul A, Li F, Chung T, Vierstra RD.

Plant Cell. 2011 Oct;23(10):3761-79. doi: 10.1105/tpc.111.090993. Epub 2011 Oct 7.

13.

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.

Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X.

J Biol Chem. 2009 May 1;284(18):12297-305. doi: 10.1074/jbc.M900573200. Epub 2009 Mar 3.

14.

Atg1 kinase regulates early and late steps during autophagy.

Kijanska M, Peter M.

Autophagy. 2013 Feb 1;9(2):249-51. doi: 10.4161/auto.22584. Epub 2012 Oct 29.

15.

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.

Chan EY, Longatti A, McKnight NC, Tooze SA.

Mol Cell Biol. 2009 Jan;29(1):157-71. doi: 10.1128/MCB.01082-08. Epub 2008 Oct 20.

16.

Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.

Alers S, Löffler AS, Paasch F, Dieterle AM, Keppeler H, Lauber K, Campbell DG, Fehrenbacher B, Schaller M, Wesselborg S, Stork B.

Autophagy. 2011 Dec;7(12):1423-33.

PMID:
22024743
17.

Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila.

Nagy P, Kárpáti M, Varga A, Pircs K, Venkei Z, Takáts S, Varga K, Erdi B, Hegedűs K, Juhász G.

Autophagy. 2014 Mar;10(3):453-67. doi: 10.4161/auto.27442. Epub 2014 Jan 6.

18.

Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy.

Kabeya Y, Kamada Y, Baba M, Takikawa H, Sasaki M, Ohsumi Y.

Mol Biol Cell. 2005 May;16(5):2544-53. Epub 2005 Mar 2.

19.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

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