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Results: 1 to 20 of 123

1.

Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients.

Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczynski G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Ježek P, Pronicki M, Duszynski J, Pinton P, Wieckowski MR.

Int J Biochem Cell Biol. 2013 Jan;45(1):141-50. doi: 10.1016/j.biocel.2012.07.020. Epub 2012 Jul 31.

PMID:
22885148
[PubMed - indexed for MEDLINE]
2.

Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc.

Arany I, Clark J, Reed DK, Juncos LA.

Nephrol Dial Transplant. 2013 Jun;28(6):1417-25. doi: 10.1093/ndt/gfs596. Epub 2013 Jan 16.

PMID:
23328708
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

p66Shc mediates high-glucose and angiotensin II-induced oxidative stress renal tubular injury via mitochondrial-dependent apoptotic pathway.

Sun L, Xiao L, Nie J, Liu FY, Ling GH, Zhu XJ, Tang WB, Chen WC, Xia YC, Zhan M, Ma MM, Peng YM, Liu H, Liu YH, Kanwar YS.

Am J Physiol Renal Physiol. 2010 Nov;299(5):F1014-25. doi: 10.1152/ajprenal.00414.2010. Epub 2010 Aug 25.

PMID:
20739391
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

p66Shc-dependent apoptosis requires Lck and CamKII activity.

Patrussi L, Giommoni N, Pellegrini M, Gamberucci A, Baldari CT.

Apoptosis. 2012 Feb;17(2):174-86. doi: 10.1007/s10495-011-0663-4.

PMID:
21983898
[PubMed - indexed for MEDLINE]
5.

Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders.

Lebiedzinska M, Karkucinska-Wieckowska A, Giorgi C, Karczmarewicz E, Pronicka E, Pinton P, Duszynski J, Pronicki M, Wieckowski MR.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):952-60. doi: 10.1016/j.bbabio.2010.03.005. Epub 2010 Mar 10.

PMID:
20226758
[PubMed - indexed for MEDLINE]
Free Article
6.

p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury.

Arany I, Faisal A, Clark JS, Vera T, Baliga R, Nagamine Y.

Am J Physiol Renal Physiol. 2010 May;298(5):F1214-21. doi: 10.1152/ajprenal.00639.2009. Epub 2010 Jan 6.

PMID:
20053790
[PubMed - indexed for MEDLINE]
Free Article
7.

Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling.

Diogo CV, Suski JM, Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Pronicki M, Duszynski J, Pinton P, Portincasa P, Oliveira PJ, Wieckowski MR.

Int J Biochem Cell Biol. 2013 Jan;45(1):114-22. doi: 10.1016/j.biocel.2012.07.004. Epub 2012 Jul 7. Review.

PMID:
22776741
[PubMed - indexed for MEDLINE]
8.

The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation.

Frijhoff J, Dagnell M, Augsten M, Beltrami E, Giorgio M, Östman A.

Free Radic Biol Med. 2014 Mar;68:268-77. doi: 10.1016/j.freeradbiomed.2013.12.022. Epub 2013 Dec 27.

PMID:
24378437
[PubMed - indexed for MEDLINE]
9.

The Lifespan-regulator p66Shc in mitochondria: redox enzyme or redox sensor?

Gertz M, Steegborn C.

Antioxid Redox Signal. 2010 Nov 1;13(9):1417-28. doi: 10.1089/ars.2010.3147. Review.

PMID:
20214499
[PubMed - indexed for MEDLINE]
10.

Antioxidant defence systems and generation of reactive oxygen species in osteosarcoma cells with defective mitochondria: effect of selenium.

Wojewoda M, Duszyński J, Szczepanowska J.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):890-6. doi: 10.1016/j.bbabio.2010.01.035. Epub 2010 Feb 4.

PMID:
20138159
[PubMed - indexed for MEDLINE]
Free Article
11.

Apoptosis and oxidative stress-related diseases: the p66Shc connection.

Pellegrini M, Baldari CT.

Curr Mol Med. 2009 Apr;9(3):392-8. Review.

PMID:
19355920
[PubMed - indexed for MEDLINE]
12.

[P66shc action on resistance of colon carcinoma RKO cells to oxidative stress].

Galimov ER, Sidorenko AS, Tereshkova AV, Pletiushkina OIu, Cherniak BV, Chumakov PM.

Mol Biol (Mosk). 2012 Jan-Feb;46(1):139-46. Russian.

PMID:
22642111
[PubMed - indexed for MEDLINE]
13.

p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes.

Guo J, Gertsberg Z, Ozgen N, Steinberg SF.

Circ Res. 2009 Mar 13;104(5):660-9. doi: 10.1161/CIRCRESAHA.108.186288. Epub 2009 Jan 22.

PMID:
19168439
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The role of p66shc in taxol- and dichloroacetic acid-dependent renal toxicity.

Arany I, Clark JS, Reed D, Szabó I, Ember I, Juncos LA.

Anticancer Res. 2013 Aug;33(8):3119-22.

PMID:
23898068
[PubMed - indexed for MEDLINE]
15.

[Role of the p66Shc protein in physiological state and in pathologies].

Lebiedzińska M, Suski J, Duszyński J, Wieckowski MR.

Postepy Biochem. 2010;56(2):165-73. Review. Polish.

PMID:
20873111
[PubMed - indexed for MEDLINE]
16.

Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells.

Maj MC, Tkachyova I, Patel P, Addis JB, Mackay N, Levandovskiy V, Lee J, Lang AE, Cameron JM, Robinson BH.

Biochem Biophys Res Commun. 2010 Aug 27;399(3):331-5. doi: 10.1016/j.bbrc.2010.07.033. Epub 2010 Jul 15.

PMID:
20637729
[PubMed - indexed for MEDLINE]
17.

Mitochondria-targeted antioxidant peptide SS31 prevents hypoxia/reoxygenation-induced apoptosis by down-regulating p66Shc in renal tubular epithelial cells.

Zhao WY, Han S, Zhang L, Zhu YH, Wang LM, Zeng L.

Cell Physiol Biochem. 2013;32(3):591-600. doi: 10.1159/000354463. Epub 2013 Sep 6.

PMID:
24021885
[PubMed - indexed for MEDLINE]
18.

NARP mutation and mtDNA depletion trigger mitochondrial biogenesis which can be modulated by selenite supplementation.

Wojewoda M, Duszyński J, Szczepanowska J.

Int J Biochem Cell Biol. 2011 Aug;43(8):1178-86. doi: 10.1016/j.biocel.2011.04.011. Epub 2011 Apr 28.

PMID:
21550418
[PubMed - indexed for MEDLINE]
19.

Elevated p66Shc is associated with intracellular redox imbalance in developmentally compromised bovine embryos.

Bain NT, Madan P, Betts DH.

Mol Reprod Dev. 2013 Jan;80(1):22-34. doi: 10.1002/mrd.22128. Epub 2012 Nov 26.

PMID:
23109234
[PubMed - indexed for MEDLINE]
20.

Genistein protects against UVB-induced senescence-like characteristics in human dermal fibroblast by p66Shc down-regulation.

Wang YN, Wu W, Chen HC, Fang H.

J Dermatol Sci. 2010 Apr;58(1):19-27. doi: 10.1016/j.jdermsci.2010.02.002. Epub 2010 Feb 16.

PMID:
20211546
[PubMed - indexed for MEDLINE]

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