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Items: 1 to 20 of 74


Potential opposite roles of the extracellular signal-regulated kinase (ERK) pathway in autism spectrum and bipolar disorders.

Kalkman HO.

Neurosci Biobehav Rev. 2012 Nov;36(10):2206-13. doi: 10.1016/j.neubiorev.2012.07.008. Epub 2012 Aug 4. Review.


The 16p11.2 deletion mouse model of autism exhibits altered cortical progenitor proliferation and brain cytoarchitecture linked to the ERK MAPK pathway.

Pucilowska J, Vithayathil J, Tavares EJ, Kelly C, Karlo JC, Landreth GE.

J Neurosci. 2015 Feb 18;35(7):3190-200. doi: 10.1523/JNEUROSCI.4864-13.2015.


Protein phosphatase 2A-negative regulation of the protective signaling pathway of Ca2+/CaM-dependent ERK activation in cerebral ischemia.

Zhao J, Wu HW, Chen YJ, Tian HP, Li LX, Han X, Guo J.

J Neurosci Res. 2008 Sep;86(12):2733-45. doi: 10.1002/jnr.21712.


Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin.

Jeon SH, Yoon JY, Park YN, Jeong WJ, Kim S, Jho EH, Surh YJ, Choi KY.

J Biol Chem. 2007 May 11;282(19):14482-92. Epub 2007 Mar 20.


Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.

Ikenoue T, Hikiba Y, Kanai F, Aragaki J, Tanaka Y, Imamura J, Imamura T, Ohta M, Ijichi H, Tateishi K, Kawakami T, Matsumura M, Kawabe T, Omata M.

Cancer Res. 2004 May 15;64(10):3428-35.


Non-photic phase shifting of the circadian clock: role of the extracellular signal-responsive kinases I/II/mitogen-activated protein kinase pathway.

Antle MC, Tse F, Koke SJ, Sterniczuk R, Hagel K.

Eur J Neurosci. 2008 Dec;28(12):2511-8. doi: 10.1111/j.1460-9568.2008.06533.x.


Hyul-Tong-Ryung suppresses PMA-induced MMP-9 expression by inhibiting AP-1-mediated gene expression via ERK 1/2 signaling pathway in MCF-7 human breast cancer cells.

Kim KS, Yao L, Lee YC, Chung E, Kim KM, Kwak YJ, Kim SJ, Cui Z, Lee JH.

Immunopharmacol Immunotoxicol. 2010 Dec;32(4):600-6. doi: 10.3109/08923971003610817. Epub 2010 Feb 4.


Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices.

Vanhoutte P, Barnier JV, Guibert B, Pagès C, Besson MJ, Hipskind RA, Caboche J.

Mol Cell Biol. 1999 Jan;19(1):136-46.


Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.

Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.

J Pharmacol Exp Ther. 2009 Jun;329(3):1063-70. doi: 10.1124/jpet.108.147306. Epub 2009 Mar 3.


Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway.

Orton RJ, Adriaens ME, Gormand A, Sturm OE, Kolch W, Gilbert DR.

BMC Syst Biol. 2009 Oct 5;3:100. doi: 10.1186/1752-0509-3-100.


Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway.

Subramaniam S, Shahani N, Strelau J, Laliberté C, Brandt R, Kaplan D, Unsicker K.

J Neurosci. 2005 Mar 16;25(11):2838-52.


Shift from extracellular signal-regulated kinase to AKT/cAMP response element-binding protein pathway increases survival-motor-neuron expression in spinal-muscular-atrophy-like mice and patient cells.

Branchu J, Biondi O, Chali F, Collin T, Leroy F, Mamchaoui K, Makoukji J, Pariset C, Lopes P, Massaad C, Chanoine C, Charbonnier F.

J Neurosci. 2013 Mar 6;33(10):4280-94. doi: 10.1523/JNEUROSCI.2728-12.2013.


Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways.

Dobbin E, Graham C, Corrigan PM, Thomas KG, Freeburn RW, Wheadon H.

Exp Hematol. 2009 Jan;37(1):111-121. doi: 10.1016/j.exphem.2008.09.012.


Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.

Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M.

Cancer Res. 2004 Oct 1;64(19):7156-68.

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