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Results: 1 to 20 of 104

1.

Human midbrain precursors activate the expected developmental genetic program and differentiate long-term to functional A9 dopamine neurons in vitro. Enhancement by Bcl-X(L).

Seiz EG, Ramos-Gómez M, Courtois ET, Tønnesen J, Kokaia M, Liste Noya I, Martínez-Serrano A.

Exp Cell Res. 2012 Nov 15;318(19):2446-59. doi: 10.1016/j.yexcr.2012.07.018. Epub 2012 Aug 2.

PMID:
22884477
[PubMed - indexed for MEDLINE]
2.

In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.

Courtois ET, Castillo CG, Seiz EG, Ramos M, Bueno C, Liste I, Martínez-Serrano A.

J Biol Chem. 2010 Mar 26;285(13):9881-97. doi: 10.1074/jbc.M109.054312. Epub 2010 Jan 27.

PMID:
20106970
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Long term behavioral effects of functional dopaminergic neurons generated from human neural stem cells in the rat 6-OH-DA Parkinson's disease model. Effects of the forced expression of BCL-X(L).

Ramos-Moreno T, Castillo CG, Martínez-Serrano A.

Behav Brain Res. 2012 Jun 15;232(1):225-32. doi: 10.1016/j.bbr.2012.04.020. Epub 2012 Apr 17.

PMID:
22537773
[PubMed - indexed for MEDLINE]
4.

Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3.

Roybon L, Hjalt T, Christophersen NS, Li JY, Brundin P.

J Neurosci. 2008 Apr 2;28(14):3644-56. doi: 10.1523/JNEUROSCI.0311-08.2008.

PMID:
18385323
[PubMed - indexed for MEDLINE]
Free Article
5.

The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons.

Chung S, Hedlund E, Hwang M, Kim DW, Shin BS, Hwang DY, Kang UJ, Isacson O, Kim KS.

Mol Cell Neurosci. 2005 Feb;28(2):241-52.

PMID:
15691706
[PubMed - indexed for MEDLINE]
6.

Fate of midbrain dopaminergic neurons controlled by the engrailed genes.

Simon HH, Saueressig H, Wurst W, Goulding MD, O'Leary DD.

J Neurosci. 2001 May 1;21(9):3126-34.

PMID:
11312297
[PubMed - indexed for MEDLINE]
Free Article
7.

Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons.

Hwang DY, Hong S, Jeong JW, Choi S, Kim H, Kim J, Kim KS.

J Neurochem. 2009 Dec;111(5):1202-12. doi: 10.1111/j.1471-4159.2009.06404.x. Epub 2009 Sep 24.

PMID:
19780901
[PubMed - indexed for MEDLINE]
8.

Functional roles of Nurr1, Pitx3, and Lmx1a in neurogenesis and phenotype specification of dopamine neurons during in vitro differentiation of embryonic stem cells.

Hong S, Chung S, Leung K, Hwang I, Moon J, Kim KS.

Stem Cells Dev. 2014 Mar 1;23(5):477-87. doi: 10.1089/scd.2013.0406. Epub 2013 Dec 4.

PMID:
24172139
[PubMed - indexed for MEDLINE]
9.

Specification of dopaminergic subsets involves interplay of En1 and Pitx3.

Veenvliet JV, Dos Santos MT, Kouwenhoven WM, von Oerthel L, Lim JL, van der Linden AJ, Koerkamp MJ, Holstege FC, Smidt MP.

Development. 2013 Aug;140(16):3373-84. doi: 10.1242/dev.094565. Epub 2013 Jul 17. Erratum in: Development. 2013 Oct;140(19):4116.

PMID:
23863478
[PubMed - indexed for MEDLINE]
Free Article
10.

The generation of dopaminergic neurons by human neural stem cells is enhanced by Bcl-XL, both in vitro and in vivo.

Liste I, García-García E, Martínez-Serrano A.

J Neurosci. 2004 Dec 1;24(48):10786-95.

PMID:
15574729
[PubMed - indexed for MEDLINE]
Free Article
11.

In-vitro analysis of Pitx3 in mesodiencephalic dopaminergic neuron maturation.

Papanikolaou T, Amano T, Lennington J, Sink K, Farrar AM, Salamone J, Yang X, Conover JC.

Eur J Neurosci. 2009 Jun;29(12):2264-75. doi: 10.1111/j.1460-9568.2009.06784.x. Epub 2009 Jun 8.

PMID:
19508691
[PubMed - indexed for MEDLINE]
12.

The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed.

Alavian KN, Jeddi S, Naghipour SI, Nabili P, Licznerski P, Tierney TS.

J Biomed Sci. 2014 Apr 1;21:27. doi: 10.1186/1423-0127-21-27. Review.

PMID:
24685177
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Generation and properties of a new human ventral mesencephalic neural stem cell line.

Villa A, Liste I, Courtois ET, Seiz EG, Ramos M, Meyer M, Juliusson B, Kusk P, Martínez-Serrano A.

Exp Cell Res. 2009 Jul 1;315(11):1860-74. doi: 10.1016/j.yexcr.2009.03.011. Epub 2009 Mar 24.

PMID:
19327351
[PubMed - indexed for MEDLINE]
14.

Gender segregation in gene expression and vulnerability to oxidative stress induced injury in ventral mesencephalic cultures of dopamine neurons.

Tao Q, Fan X, Li T, Tang Y, Yang D, Le W.

J Neurosci Res. 2012 Jan;90(1):167-78. doi: 10.1002/jnr.22729. Epub 2011 Sep 14.

PMID:
21919034
[PubMed - indexed for MEDLINE]
15.

Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells.

Sánchez-Danés A, Consiglio A, Richaud Y, Rodríguez-Pizà I, Dehay B, Edel M, Bové J, Memo M, Vila M, Raya A, Izpisua Belmonte JC.

Hum Gene Ther. 2012 Jan;23(1):56-69. doi: 10.1089/hum.2011.054. Epub 2011 Nov 17.

PMID:
21877920
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Midbrain dopaminergic neurons: determination of their developmental fate by transcription factors.

Simon HH, Bhatt L, Gherbassi D, Sgadó P, Alberí L.

Ann N Y Acad Sci. 2003 Jun;991:36-47.

PMID:
12846972
[PubMed - indexed for MEDLINE]
17.

Midbrain cues dictate differentiation of human dental pulp stem cells towards functional dopaminergic neurons.

Kanafi M, Majumdar D, Bhonde R, Gupta P, Datta I.

J Cell Physiol. 2014 Oct;229(10):1369-77. doi: 10.1002/jcp.24570.

PMID:
24477667
[PubMed - indexed for MEDLINE]
18.

Pitx3 is required for development of substantia nigra dopaminergic neurons.

Nunes I, Tovmasian LT, Silva RM, Burke RE, Goff SP.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4245-50. Epub 2003 Mar 24.

PMID:
12655058
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Nigrostriatal innervation is preserved in Nurr1-null mice, although dopaminergic neuron precursors are arrested from terminal differentiation.

Witta J, Baffi JS, Palkovits M, Mezey E, Castillo SO, Nikodem VM.

Brain Res Mol Brain Res. 2000 Dec 8;84(1-2):67-78.

PMID:
11113533
[PubMed - indexed for MEDLINE]
20.

Bdnf gene is a downstream target of Nurr1 transcription factor in rat midbrain neurons in vitro.

Volpicelli F, Caiazzo M, Greco D, Consales C, Leone L, Perrone-Capano C, Colucci D'Amato L, di Porzio U.

J Neurochem. 2007 Jul;102(2):441-53. Epub 2007 May 15.

PMID:
17506860
[PubMed - indexed for MEDLINE]

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